SLAMF7: Difference between revisions

Jump to navigation Jump to search
imported>AnomieBOT
Fixing reference errors
 
Line 21: Line 21:
* {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = Oct 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
* {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = Oct 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
* {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = Jan 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
* {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = Jan 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
* {{cite journal | vauthors = Stark S, Watzl C | title = 2B4 (CD244), NTB-A and CRACC (CS1) stimulate cytotoxicity but no proliferation in human NK cells | journal = International Immunology | volume = 18 | issue = 2 | pages = 241–7 | date = Feb 2006 | pmid = 16410313 | doi = 10.1093/intimm/dxh358 }}
* {{cite journal | vauthors = Stark S, Watzl C | title = 2B4 (CD244), NTB-A and CRACC (CS1) stimulate cytotoxicity but no proliferation in human NK cells | journal = [[International Immunology]] | volume = 18 | issue = 2 | pages = 241–7 | date = Feb 2006 | pmid = 16410313 | doi = 10.1093/intimm/dxh358 }}
* {{cite journal | vauthors = Lee JK, Mathew SO, Vaidya SV, Kumaresan PR, Mathew PA | title = CS1 (CRACC, CD319) induces proliferation and autocrine cytokine expression on human B lymphocytes | journal = Journal of Immunology | volume = 179 | issue = 7 | pages = 4672–8 | date = Oct 2007 | pmid = 17878365 | doi = 10.4049/jimmunol.179.7.4672 }}
* {{cite journal | vauthors = Lee JK, Mathew SO, Vaidya SV, Kumaresan PR, Mathew PA | title = CS1 (CRACC, CD319) induces proliferation and autocrine cytokine expression on human B lymphocytes | journal = Journal of Immunology | volume = 179 | issue = 7 | pages = 4672–8 | date = Oct 2007 | pmid = 17878365 | doi = 10.4049/jimmunol.179.7.4672 }}
* {{cite journal | vauthors = Malaer JD, Mathew PA | title = CS1 (SLAMF7, CD319) is an effective immunotherapeutic target for multiple myeloma | journal = American Journal of Cancer Research | volume = 7 | issue = 8 | pages = 1637–41 | date = Aug 2017 | pmid = 28861320 }}
{{refend}}
{{refend}}


{{gene-1-stub}}
{{gene-1-stub}}

Latest revision as of 02:43, 20 June 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

SLAM family member 7 is a protein that in humans is encoded by the SLAMF7 gene.[1][2][3]

The surface antigen CD319 (SLAMF7) is a robust marker of normal plasma cells and malignant plasma cells in multiple myeloma. In contrast to CD138 (the traditional plasma cell marker), CD319/SLAMF7 is much more stable and allows robust isolation of malignant plasma cells from delayed or even cryopreserved samples.[4]

Elotuzumab is an antibody that targets this protein.

References

  1. Murphy JJ, Hobby P, Vilarino-Varela J, Bishop B, Iordanidou P, Sutton BJ, Norton JD (Feb 2002). "A novel immunoglobulin superfamily receptor (19A) related to CD2 is expressed on activated lymphocytes and promotes homotypic B-cell adhesion". The Biochemical Journal. 361 (Pt 3): 431–6. doi:10.1042/0264-6021:3610431. PMC 1222324. PMID 11802771.
  2. Boles KS, Mathew PA (Feb 2001). "Molecular cloning of CS1, a novel human natural killer cell receptor belonging to the CD2 subset of the immunoglobulin superfamily". Immunogenetics. 52 (3–4): 302–7. doi:10.1007/s002510000274. PMID 11220635.
  3. "Entrez Gene: SLAMF7 SLAM family member 7".
  4. Frigyesi I, Adolfsson J, Ali M, Christophersen MK, Johnsson E, Turesson I, Gullberg U, Hansson M, Nilsson B (Feb 2014). "Robust isolation of malignant plasma cells in multiple myeloma". Blood. 123 (9): 1336–40. doi:10.1182/blood-2013-09-529800. PMID 24385542.

Further reading