RBM15: Difference between revisions

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'''Putative RNA-binding protein 15''' is a [[protein]] that in humans is encoded by the ''RBM15'' [[gene]].<ref name="pmid11431691">{{cite journal | vauthors = Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X, Bouman D, Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GC, Chan LC, Squire J, Scherer SW, Hitzler JK | title = Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia | journal = Nat Genet | volume = 28 | issue = 3 | pages = 220–1 |date=Jun 2001 | pmid = 11431691 | pmc =  | doi = 10.1038/90054 }}</ref><ref name="pmid11344311">{{cite journal | vauthors = Mercher T, Coniat MB, Monni R, Mauchauffe M, Nguyen Khac F, Gressin L, Mugneret F, Leblanc T, Dastugue N, Berger R, Bernard OA | title = Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia | journal = Proc Natl Acad Sci U S A | volume = 98 | issue = 10 | pages = 5776–9 |date=May 2001 | pmid = 11344311 | pmc = 33289 | doi = 10.1073/pnas.101001498 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RBM15 RNA binding motif protein 15| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64783| accessdate = }}</ref>
'''Putative RNA-binding protein 15''' is a [[protein]] that in humans is encoded by the ''RBM15'' [[gene]].<ref name="pmid11431691">{{cite journal | vauthors = Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X, Bouman D, Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GC, Chan LC, Squire J, Scherer SW, Hitzler JK | title = Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia | journal = Nat Genet | volume = 28 | issue = 3 | pages = 220–1 |date=Jun 2001 | pmid = 11431691 | pmc =  | doi = 10.1038/90054 }}</ref><ref name="pmid11344311">{{cite journal | vauthors = Mercher T, Coniat MB, Monni R, Mauchauffe M, Nguyen Khac F, Gressin L, Mugneret F, Leblanc T, Dastugue N, Berger R, Bernard OA | title = Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia | journal = Proc Natl Acad Sci U S A | volume = 98 | issue = 10 | pages = 5776–9 |date=May 2001 | pmid = 11344311 | pmc = 33289 | doi = 10.1073/pnas.101001498 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RBM15 RNA binding motif protein 15| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64783| accessdate = }}</ref>
It is a [[RNA-binding protein]] that acts as a key regulator of [[N6-Methyladenosine]] (m<sup>6</sup>A) methylation of [[RNAs]]<ref name="uniprot">{{cite web | title = UniProtKB - Q96T37 (RBM15_HUMAN) | url = https://www.uniprot.org/uniprot/Q96T37 |accessdate = 29 October 2018}}</ref>


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Latest revision as of 16:27, 29 October 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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n/a

RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Putative RNA-binding protein 15 is a protein that in humans is encoded by the RBM15 gene.[1][2][3] It is a RNA-binding protein that acts as a key regulator of N6-Methyladenosine (m6A) methylation of RNAs[4]


References

  1. Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X, Bouman D, Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GC, Chan LC, Squire J, Scherer SW, Hitzler JK (Jun 2001). "Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia". Nat Genet. 28 (3): 220–1. doi:10.1038/90054. PMID 11431691.
  2. Mercher T, Coniat MB, Monni R, Mauchauffe M, Nguyen Khac F, Gressin L, Mugneret F, Leblanc T, Dastugue N, Berger R, Bernard OA (May 2001). "Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia". Proc Natl Acad Sci U S A. 98 (10): 5776–9. doi:10.1073/pnas.101001498. PMC 33289. PMID 11344311.
  3. "Entrez Gene: RBM15 RNA binding motif protein 15".
  4. "UniProtKB - Q96T37 (RBM15_HUMAN)". Retrieved 29 October 2018.

Further reading