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| Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two [[intelectin]]s may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.<ref>{{cite journal | vauthors = Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT | title = Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition | journal = The Journal of Biological Chemistry | volume = 291 | issue = 11 | pages = 5596–610 | date = March 2016 | pmid = 26755729 | doi = 10.1074/jbc.M115.709212 }}</ref> | | Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two [[intelectin]]s may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.<ref>{{cite journal | vauthors = Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT | title = Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition | journal = The Journal of Biological Chemistry | volume = 291 | issue = 11 | pages = 5596–610 | date = March 2016 | pmid = 26755729 | doi = 10.1074/jbc.M115.709212 | pmc = 4786701 }}</ref> |
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| == See also == | | == See also == |
Latest revision as of 21:23, 15 May 2018
Intelectin 2 is a protein that in humans is encoded by the ITLN2 gene.[1]
Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two intelectins may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.[2]
See also
References
