SLC8B1: Difference between revisions

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{{Underlinked|date=January 2014}}
{{Infobox_gene}}
{{Infobox_gene}}
'''Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1''' is a [[protein]] that in humans is encoded by the SLC8B1 [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 | url = https://www.ncbi.nlm.nih.gov/gene/80024 }}</ref>


'''Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1''' is a [[protein]] that in humans is encoded by the SLC8B1 [[gene]].
== Function ==
<ref name="entrez">
{{cite web
| title = Entrez Gene: Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
| url = https://www.ncbi.nlm.nih.gov/gene/80024
| accessdate = 2014-01-05 <!-- T23:27:57.645528-08:00 -->
}}</ref>


==Function==
SLC24A6 belongs to a family of [[Potassium-dependent sodium-calcium exchanger]]s that maintain cellular [[Calcium in biology|calcium]] homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion.<ref name="pmid14625281">{{cite journal | vauthors = Cai X, Lytton J | title = Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6 | journal = The Journal of Biological Chemistry | volume = 279 | issue = 7 | pages = 5867–76 | date = February 2004 | pmid = 14625281 | doi = 10.1074/jbc.M310908200 }}</ref>
 
SLC24A6 belongs to a family of potassium-dependent sodium/calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion (Cai and Lytton, 2004 [PubMed 14625281]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## CDS exon combination :: BC098360.1, AY601759.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END##


== References ==
== References ==
{{reflist}}
{{reflist}}


== Further reading ==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
*{{Cite journal  
* {{cite journal | vauthors = Boyman L, Williams GS, Khananshvili D, Sekler I, Lederer WJ | title = NCLX: the mitochondrial sodium calcium exchanger | journal = Journal of Molecular and Cellular Cardiology | volume = 59 | pages = 205–13 | date = June 2013 | pmid = 23538132 | pmc = 3951392 | doi = 10.1016/j.yjmcc.2013.03.012 }}
| last1 = Boyman | first1 = L.
* {{cite journal | vauthors = Palty R, Ohana E, Hershfinkel M, Volokita M, Elgazar V, Beharier O, Silverman WF, Argaman M, Sekler I | title = Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger | journal = The Journal of Biological Chemistry | volume = 279 | issue = 24 | pages = 25234–40 | date = June 2004 | pmid = 15060069 | pmc = | doi = 10.1074/jbc.M401229200 }}
| last2 = Williams | first2 = G. S. B.
* {{cite journal | vauthors = Aslibekyan S, An P, Frazier-Wood AC, Kabagambe EK, Irvin MR, Straka RJ, Tiwari HK, Tsai MY, Hopkins PN, Borecki IB, Ordovas JM, Arnett DK | title = Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network | journal = Nutrition, Metabolism, and Cardiovascular Diseases | volume = 23 | issue = 10 | pages = 987–94 | date = October 2013 | pmid = 23149075 | pmc = 3578131 | doi = 10.1016/j.numecd.2012.07.010 }}
| last3 = Khananshvili | first3 = D.
| last4 = Sekler | first4 = I.
| last5 = Lederer | first5 = W. J.
| title = NCLX: The mitochondrial sodium calcium exchanger  
| doi = 10.1016/j.yjmcc.2013.03.012
| journal = Journal of Molecular and Cellular Cardiology  
| volume = 59  
| pages = 205–213
| year = 2013  
| pmid = 23538132  
| pmc = 3951392
}}
*{{Cite journal  
| last1 = Palty | first1 = R.
| last2 = Ohana | first2 = E.
| last3 = Hershfinkel | first3 = M.
| last4 = Volokita | first4 = M.
| last5 = Elgazar | first5 = V.
| last6 = Beharier | first6 = O.
| last7 = Silverman | first7 = W. F.
| last8 = Argaman | first8 = M.
| last9 = Sekler | first9 = I.
| title = Lithium-Calcium Exchange is Mediated by a Distinct Potassium-independent Sodium-Calcium Exchanger
| doi = 10.1074/jbc.M401229200
| journal = Journal of Biological Chemistry  
| volume = 279  
| issue = 24  
| pages = 25234–25240
| year = 2004  
| pmid = 15060069  
| pmc =  
}}
*{{Cite journal  
| last1 = Aslibekyan | first1 = S.
| last2 = An | first2 = P.
| last3 = Frazier-Wood | first3 = A. C.
| last4 = Kabagambe | first4 = E. K.
| last5 = Irvin | first5 = M. R.
| last6 = Straka | first6 = R. J.
| last7 = Tiwari | first7 = H. K.
| last8 = Tsai | first8 = M. Y.
| last9 = Hopkins | first9 = P. N.
| last10 = Borecki | first10 = I. B.
| last11 = Ordovas | first11 = J. M.
| last12 = Arnett | first12 = D. K.
| doi = 10.1016/j.numecd.2012.07.010
| title = Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network  
| journal = Nutrition, Metabolism and Cardiovascular Diseases  
| volume = 23  
| issue = 10  
| pages = 987–994
| year = 2013  
| pmid = 23149075  
| pmc =3578131  
}}
*{{Cite journal
| last1 = Cai | first1 = X.
| last2 = Lytton | first2 = J.
| title = Molecular Cloning of a Sixth Member of the K+-dependent Na+/Ca2+ Exchanger Gene Family, NCKX6
| doi = 10.1074/jbc.M310908200
| journal = Journal of Biological Chemistry
| volume = 279
| issue = 7
| pages = 5867–5876
| year = 2003
| pmid = 14625281
| pmc =
}}
 
{{refend}}
{{refend}}


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[[Category:Genes]]
[[Category:Genes]]
[[Category:Human proteins]]
[[Category:Human proteins]]


{{gene-12-stub}}
{{gene-12-stub}}

Latest revision as of 22:50, 20 January 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 is a protein that in humans is encoded by the SLC8B1 gene.[1]

Function

SLC24A6 belongs to a family of Potassium-dependent sodium-calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion.[2]

References

  1. "Entrez Gene: Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1".
  2. Cai X, Lytton J (February 2004). "Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6". The Journal of Biological Chemistry. 279 (7): 5867–76. doi:10.1074/jbc.M310908200. PMID 14625281.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.