CDK5RAP1: Difference between revisions

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'''CDK5 regulatory subunit-associated protein 1''' is a [[protein]] that in humans is encoded by the ''CDK5RAP1'' [[gene]].<ref name="pmid10721722">{{cite journal | vauthors = Ching YP, Qi Z, Wang JH | title = Cloning of three novel neuronal Cdk5 activator binding proteins | journal = Gene | volume = 242 | issue = 1–2 | pages = 285–94 |date=Apr 2000 | pmid = 10721722 | pmc =  | doi =10.1016/S0378-1119(99)00499-0  }}</ref><ref name="pmid11882646">{{cite journal | vauthors = Ching YP, Pang AS, Lam WH, Qi RZ, Wang JH | title = Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor | journal = J Biol Chem | volume = 277 | issue = 18 | pages = 15237–40 |date=Apr 2002 | pmid = 11882646 | pmc =  | doi = 10.1074/jbc.C200032200 }}</ref><ref name="pmid15329498">{{cite journal | vauthors = Zou X, Ji C, Jin F, Liu J, Wu M, Zheng H, Wang Y, Li X, Xu J, Gu S, Xie Y, Mao Y | title = Cloning, characterization and expression of CDK5RAP1_v3 and CDK5RAP1_v4, two novel splice variants of human CDK5RAP1 | journal = Genes Genet Syst | volume = 79 | issue = 3 | pages = 177–82 |date=Aug 2004 | pmid = 15329498 | pmc =  | doi =10.1266/ggs.79.177  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CDK5RAP1 CDK5 regulatory subunit associated protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51654| accessdate = }}</ref>
'''CDK5 regulatory subunit-associated protein 1''' is a [[protein]] that in humans is encoded by the ''CDK5RAP1'' [[gene]].<ref name="pmid10721722">{{cite journal | vauthors = Ching YP, Qi Z, Wang JH | title = Cloning of three novel neuronal Cdk5 activator binding proteins | journal = Gene | volume = 242 | issue = 1–2 | pages = 285–94 |date=Apr 2000 | pmid = 10721722 | pmc =  | doi =10.1016/S0378-1119(99)00499-0  }}</ref><ref name="pmid11882646">{{cite journal | vauthors = Ching YP, Pang AS, Lam WH, Qi RZ, Wang JH | title = Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor | journal = J Biol Chem | volume = 277 | issue = 18 | pages = 15237–40 |date=Apr 2002 | pmid = 11882646 | pmc =  | doi = 10.1074/jbc.C200032200 }}</ref><ref name="pmid15329498">{{cite journal | vauthors = Zou X, Ji C, Jin F, Liu J, Wu M, Zheng H, Wang Y, Li X, Xu J, Gu S, Xie Y, Mao Y | title = Cloning, characterization and expression of CDK5RAP1_v3 and CDK5RAP1_v4, two novel splice variants of human CDK5RAP1 | journal = Genes Genet Syst | volume = 79 | issue = 3 | pages = 177–82 |date=Aug 2004 | pmid = 15329498 | pmc =  | doi =10.1266/ggs.79.177  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CDK5RAP1 CDK5 regulatory subunit associated protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51654| accessdate = }}</ref>
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| summary_text = Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.<ref name="entrez"/>
| summary_text = [[Neuronal]] CDC2-like [[kinase]], which is involved in the regulation of neuronal [[cell differentiation|differentiation]], is composed of a catalytic subunit, [[CDK5]], and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple [[transcript variants]] exist for this gene, but the full-length natures of only two have been determined.<ref name="entrez"/>
}}
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Revision as of 12:57, 12 March 2018

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Identifiers
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External IDsGeneCards: [1]
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SpeciesHumanMouse
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CDK5 regulatory subunit-associated protein 1 is a protein that in humans is encoded by the CDK5RAP1 gene.[1][2][3][4]

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.[4]

References

  1. ↑ Ching YP, Qi Z, Wang JH (Apr 2000). "Cloning of three novel neuronal Cdk5 activator binding proteins". Gene. 242 (1–2): 285–94. doi:10.1016/S0378-1119(99)00499-0. PMID 10721722.
  2. ↑ Ching YP, Pang AS, Lam WH, Qi RZ, Wang JH (Apr 2002). "Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor". J Biol Chem. 277 (18): 15237–40. doi:10.1074/jbc.C200032200. PMID 11882646.
  3. ↑ Zou X, Ji C, Jin F, Liu J, Wu M, Zheng H, Wang Y, Li X, Xu J, Gu S, Xie Y, Mao Y (Aug 2004). "Cloning, characterization and expression of CDK5RAP1_v3 and CDK5RAP1_v4, two novel splice variants of human CDK5RAP1". Genes Genet Syst. 79 (3): 177–82. doi:10.1266/ggs.79.177. PMID 15329498.
  4. ↑ 4.0 4.1 "Entrez Gene: CDK5RAP1 CDK5 regulatory subunit associated protein 1".

External links

Further reading



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