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'''Secretoglobin family 3A member 1''' is a [[protein]] that in humans is encoded by the ''SCGB3A1'' [[gene]].<ref name="pmid11682631">{{cite journal | vauthors = Niimi T, Keck-Waggoner CL, Popescu NC, Zhou Y, Levitt RC, Kimura S | title = UGRP1, a uteroglobin/Clara cell secretory protein-related protein, is a novel lung-enriched downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor | journal = Mol Endocrinol | volume = 15 | issue = 11 | pages = 2021–36 |date=Oct 2001 | pmid = 11682631 | pmc =  | doi =10.1210/me.15.11.2021  }}</ref><ref name="pmid11481438">{{cite journal | vauthors = Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K | title = HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells | journal = Proc Natl Acad Sci U S A | volume = 98 | issue = 17 | pages = 9796–801 |date=Aug 2001 | pmid = 11481438 | pmc = 55532 | doi = 10.1073/pnas.171138398 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SCGB3A1 secretoglobin, family 3A, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92304| accessdate = }}</ref>
'''Secretoglobin family 3A member 1''' is a [[protein]] that in humans is encoded by the ''SCGB3A1'' [[gene]].<ref name="pmid11481438">{{cite journal | vauthors = Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K | title = HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 98 | issue = 17 | pages = 9796–801 | date = August 2001 | pmid = 11481438 | pmc = 55532 | doi = 10.1073/pnas.171138398 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SCGB3A1 secretoglobin, family 3A, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92304| access-date = }}</ref>


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==References==
== References ==
{{reflist}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Porter D, Lahti-Domenici J, Torres-Arzayus M, Chin L, Polyak K | title = Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues | journal = Mechanisms of Development | volume = 114 | issue = 1-2 | pages = 201–4 | date = June 2002 | pmid = 12175512 | doi = 10.1016/S0925-4773(02)00056-4 }}
| citations =
* {{cite journal | vauthors = Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR | title = Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways | journal = American Journal of Respiratory and Critical Care Medicine | volume = 166 | issue = 11 | pages = 1498–509 | date = December 2002 | pmid = 12406855 | doi = 10.1164/rccm.200204-285OC }}
*{{cite journal   |vauthors=Porter D, Lahti-Domenici J, Torres-Arzayus M, etal |title=Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues. |journal=Mech. Dev. |volume=114 |issue= 1-2 |pages= 201–4 |year= 2003 |pmid= 12175512 |doi=10.1016/S0925-4773(02)00056-4 }}
* {{cite journal | vauthors = Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic DB, Keck-Waggoner CL, Popescu NC, Kimura S | title = Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family | journal = Cytogenetic and Genome Research | volume = 97 | issue = 1-2 | pages = 120–7 | year = 2003 | pmid = 12438750 | doi = 10.1159/000064067 }}
*{{cite journal   |vauthors=Reynolds SD, Reynolds PR, Pryhuber GS, etal |title=Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. |journal=Am. J. Respir. Crit. Care Med. |volume=166 |issue= 11 |pages= 1498–509 |year= 2003 |pmid= 12406855 |doi= 10.1164/rccm.200204-285OC }}
* {{cite journal | vauthors = Krop I, Maguire P, Lahti-Domenici J, Lodeiro G, Richardson A, Johannsdottir HK, Nevanlinna H, Borg A, Gelman R, Barkardottir RB, Lindblom A, Polyak K | title = Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors | journal = Cancer Research | volume = 63 | issue = 9 | pages = 2024–7 | date = May 2003 | pmid = 12727813 | doi =  }}
*{{cite journal   |vauthors=Niimi T, Copeland NG, Gilbert DJ, etal |title=Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family. |journal=Cytogenet. Genome Res. |volume=97 |issue= 1-2 |pages= 120–7 |year= 2003 |pmid= 12438750 |doi=10.1159/000064067 }}
* {{cite journal | vauthors = Bin LH, Nielson LD, Liu X, Mason RJ, Shu HB | title = Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair | journal = Journal of Immunology | volume = 171 | issue = 2 | pages = 924–30 | date = July 2003 | pmid = 12847263 | doi = 10.4049/jimmunol.171.2.924 }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
* {{cite journal | vauthors = Fackler MJ, McVeigh M, Evron E, Garrett E, Mehrotra J, Polyak K, Sukumar S, Argani P | title = DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in <!-- not a mistake --> in situ and invasive lobular breast carcinoma | journal = International Journal of Cancer | volume = 107 | issue = 6 | pages = 970–5 | date = December 2003 | pmid = 14601057 | doi = 10.1002/ijc.11508 }}
*{{cite journal   |vauthors=Krop I, Maguire P, Lahti-Domenici J, etal |title=Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors. |journal=Cancer Res. |volume=63 |issue= 9 |pages= 2024–7 |year= 2003 |pmid= 12727813 |doi=  }}
* {{cite journal | vauthors = Tisserand P, Fouquet C, Barrois M, Gallou C, Dendale R, Stoppa-Lyonnet D, Sastre-Garau X, Fourquet A, Soussi T | title = Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors | journal = Cancer Biology & Therapy | volume = 2 | issue = 5 | pages = 559–63 | year = 2004 | pmid = 14614327 | doi = 10.4161/cbt.2.5.511 }}
*{{cite journal   |vauthors=Bin LH, Nielson LD, Liu X, etal |title=Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair. |journal=J. Immunol. |volume=171 |issue= 2 |pages= 924–30 |year= 2003 |pmid= 12847263 |doi= 10.4049/jimmunol.171.2.924}}
* {{cite journal | vauthors = Marchetti A, Barassi F, Martella C, Chella A, Salvatore S, Castrataro A, Mucilli F, Sacco R, Buttitta F | title = Down regulation of high in normal-1 (HIN-1) is a frequent event in stage I non-small cell lung cancer and correlates with poor clinical outcome | journal = Clinical Cancer Research | volume = 10 | issue = 4 | pages = 1338–43 | date = February 2004 | pmid = 14977834 | doi = 10.1158/1078-0432.CCR-1174-03 }}
*{{cite journal   |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003  | pmc=403697 }}
* {{cite journal | vauthors = Zhang Z, Henzel WJ | title = Signal peptide prediction based on analysis of experimentally verified cleavage sites | journal = Protein Science | volume = 13 | issue = 10 | pages = 2819–24 | date = October 2004 | pmid = 15340161 | pmc = 2286551 | doi = 10.1110/ps.04682504 }}
*{{cite journal  |vauthors=Fackler MJ, McVeigh M, Evron E, etal |title=DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma. |journal=Int. J. Cancer |volume=107 |issue= 6 |pages= 970–5 |year= 2004 |pmid= 14601057 |doi= 10.1002/ijc.11508 }}
* {{cite journal | vauthors = Krop I, Player A, Tablante A, Taylor-Parker M, Lahti-Domenici J, Fukuoka J, Batra SK, Papadopoulos N, Richards WG, Sugarbaker DJ, Wright RL, Shim J, Stamey TA, Sellers WR, Loda M, Meyerson M, Hruban R, Jen J, Polyak K | title = Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types | journal = Molecular Cancer Research | volume = 2 | issue = 9 | pages = 489–94 | date = September 2004 | pmid = 15383627 | doi =  }}
*{{cite journal   |vauthors=Tisserand P, Fouquet C, Barrois M, etal |title=Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors. |journal=Cancer Biol. Ther. |volume=2 |issue= 5 |pages= 559–63 |year= 2004 |pmid= 14614327 |doi= 10.4161/cbt.2.5.511}}
* {{cite journal | vauthors = Shigematsu H, Suzuki M, Takahashi T, Miyajima K, Toyooka S, Shivapurkar N, Tomlinson GE, Mastrangelo D, Pass HI, Brambilla E, Sathyanarayana UG, Czerniak B, Fujisawa T, Shimizu N, Gazdar AF | title = Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies | journal = International Journal of Cancer | volume = 113 | issue = 4 | pages = 600–4 | date = February 2005 | pmid = 15472908 | doi = 10.1002/ijc.20622 }}
*{{cite journal   |vauthors=Marchetti A, Barassi F, Martella C, etal |title=Down regulation of high in normal-1 (HIN-1) is a frequent event in stage I non-small cell lung cancer and correlates with poor clinical outcome. |journal=Clin. Cancer Res. |volume=10 |issue= 4 |pages= 1338–43 |year= 2004 |pmid= 14977834 |doi=10.1158/1078-0432.CCR-1174-03 }}
* {{cite journal | vauthors = Krop I, Parker MT, Bloushtain-Qimron N, Porter D, Gelman R, Sasaki H, Maurer M, Terry MB, Parsons R, Polyak K | title = HIN-1, an inhibitor of cell growth, invasion, and AKT activation | journal = Cancer Research | volume = 65 | issue = 21 | pages = 9659–69 | date = November 2005 | pmid = 16266985 | doi = 10.1158/0008-5472.CAN-05-1663 }}
*{{cite journal | vauthors=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 | pmc=2286551 }}
* {{cite journal | vauthors = Yang Q, Kiernan CM, Tian Y, Salwen HR, Chlenski A, Brumback BA, London WB, Cohn SL | title = Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome | journal = Clinical Cancer Research | volume = 13 | issue = 11 | pages = 3191–7 | date = June 2007 | pmid = 17545522 | doi = 10.1158/1078-0432.CCR-06-2846 }}
*{{cite journal   |vauthors=Krop I, Player A, Tablante A, etal |title=Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types. |journal=Mol. Cancer Res. |volume=2 |issue= 9 |pages= 489–94 |year= 2005 |pmid= 15383627 |doi=  }}
* {{cite journal | vauthors = Wu Q, Lothe RA, Ahlquist T, Silins I, Tropé CG, Micci F, Nesland JM, Suo Z, Lind GE | title = DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets | journal = Molecular Cancer | volume = 6 | issue =  | pages = 45 | date = July 2007 | pmid = 17623056 | pmc = 1964763 | doi = 10.1186/1476-4598-6-45 }}
*{{cite journal   |vauthors=Shigematsu H, Suzuki M, Takahashi T, etal |title=Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. |journal=Int. J. Cancer |volume=113 |issue= 4 |pages= 600–4 |year= 2005 |pmid= 15472908 |doi= 10.1002/ijc.20622 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal  |vauthors=Krop I, Parker MT, Bloushtain-Qimron N, etal |title=HIN-1, an inhibitor of cell growth, invasion, and AKT activation. |journal=Cancer Res. |volume=65 |issue= 21 |pages= 9659–69 |year= 2005 |pmid= 16266985 |doi= 10.1158/0008-5472.CAN-05-1663 }}
*{{cite journal   |vauthors=Yang Q, Kiernan CM, Tian Y, etal |title=Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome. |journal=Clin. Cancer Res. |volume=13 |issue= 11 |pages= 3191–7 |year= 2007 |pmid= 17545522 |doi= 10.1158/1078-0432.CCR-06-2846 }}
*{{cite journal   |vauthors=Wu Q, Lothe RA, Ahlquist T, etal |title=DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets. |journal=Mol. Cancer |volume=6 |issue=  |pages= 45 |year= 2007 |pmid= 17623056 |doi= 10.1186/1476-4598-6-45 | pmc=1964763 }}
}}
{{refend}}
{{refend}}


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{{gene-5-stub}}
{{gene-5-stub}}

Latest revision as of 08:07, 19 August 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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n/a

RefSeq (mRNA)

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RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Secretoglobin family 3A member 1 is a protein that in humans is encoded by the SCGB3A1 gene.[1][2]


References

  1. ↑ Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K (August 2001). "HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells". Proceedings of the National Academy of Sciences of the United States of America. 98 (17): 9796–801. doi:10.1073/pnas.171138398. PMC 55532. PMID 11481438.
  2. ↑ "Entrez Gene: SCGB3A1 secretoglobin, family 3A, member 1".

Further reading

  • Porter D, Lahti-Domenici J, Torres-Arzayus M, Chin L, Polyak K (June 2002). "Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues". Mechanisms of Development. 114 (1–2): 201–4. doi:10.1016/S0925-4773(02)00056-4. PMID 12175512.
  • Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR (December 2002). "Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways". American Journal of Respiratory and Critical Care Medicine. 166 (11): 1498–509. doi:10.1164/rccm.200204-285OC. PMID 12406855.
  • Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic DB, Keck-Waggoner CL, Popescu NC, Kimura S (2003). "Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family". Cytogenetic and Genome Research. 97 (1–2): 120–7. doi:10.1159/000064067. PMID 12438750.
  • Krop I, Maguire P, Lahti-Domenici J, Lodeiro G, Richardson A, Johannsdottir HK, Nevanlinna H, Borg A, Gelman R, Barkardottir RB, Lindblom A, Polyak K (May 2003). "Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors". Cancer Research. 63 (9): 2024–7. PMID 12727813.
  • Bin LH, Nielson LD, Liu X, Mason RJ, Shu HB (July 2003). "Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair". Journal of Immunology. 171 (2): 924–30. doi:10.4049/jimmunol.171.2.924. PMID 12847263.
  • Fackler MJ, McVeigh M, Evron E, Garrett E, Mehrotra J, Polyak K, Sukumar S, Argani P (December 2003). "DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma". International Journal of Cancer. 107 (6): 970–5. doi:10.1002/ijc.11508. PMID 14601057.
  • Tisserand P, Fouquet C, Barrois M, Gallou C, Dendale R, Stoppa-Lyonnet D, Sastre-Garau X, Fourquet A, Soussi T (2004). "Lack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors". Cancer Biology & Therapy. 2 (5): 559–63. doi:10.4161/cbt.2.5.511. PMID 14614327.
  • Marchetti A, Barassi F, Martella C, Chella A, Salvatore S, Castrataro A, Mucilli F, Sacco R, Buttitta F (February 2004). "Down regulation of high in normal-1 (HIN-1) is a frequent event in stage I non-small cell lung cancer and correlates with poor clinical outcome". Clinical Cancer Research. 10 (4): 1338–43. doi:10.1158/1078-0432.CCR-1174-03. PMID 14977834.
  • Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
  • Krop I, Player A, Tablante A, Taylor-Parker M, Lahti-Domenici J, Fukuoka J, Batra SK, Papadopoulos N, Richards WG, Sugarbaker DJ, Wright RL, Shim J, Stamey TA, Sellers WR, Loda M, Meyerson M, Hruban R, Jen J, Polyak K (September 2004). "Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types". Molecular Cancer Research. 2 (9): 489–94. PMID 15383627.
  • Shigematsu H, Suzuki M, Takahashi T, Miyajima K, Toyooka S, Shivapurkar N, Tomlinson GE, Mastrangelo D, Pass HI, Brambilla E, Sathyanarayana UG, Czerniak B, Fujisawa T, Shimizu N, Gazdar AF (February 2005). "Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies". International Journal of Cancer. 113 (4): 600–4. doi:10.1002/ijc.20622. PMID 15472908.
  • Krop I, Parker MT, Bloushtain-Qimron N, Porter D, Gelman R, Sasaki H, Maurer M, Terry MB, Parsons R, Polyak K (November 2005). "HIN-1, an inhibitor of cell growth, invasion, and AKT activation". Cancer Research. 65 (21): 9659–69. doi:10.1158/0008-5472.CAN-05-1663. PMID 16266985.
  • Yang Q, Kiernan CM, Tian Y, Salwen HR, Chlenski A, Brumback BA, London WB, Cohn SL (June 2007). "Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome". Clinical Cancer Research. 13 (11): 3191–7. doi:10.1158/1078-0432.CCR-06-2846. PMID 17545522.
  • Wu Q, Lothe RA, Ahlquist T, Silins I, Tropé CG, Micci F, Nesland JM, Suo Z, Lind GE (July 2007). "DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets". Molecular Cancer. 6: 45. doi:10.1186/1476-4598-6-45. PMC 1964763. PMID 17623056.


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