PPP3CC: Difference between revisions
Jump to navigation
Jump to search
m →top: clean up, added underlinked tag using AWB |
m →Further reading: task, replaced: Journal of neural transmission (Vienna, Austria : 1996) → Journal of Neural Transmission |
||
| Line 23: | Line 23: | ||
*{{cite journal | author=Barrios-Rodiles M |title=High-throughput mapping of a dynamic signaling network in mammalian cells |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 |name-list-format=vanc| author2=Brown KR | author3=Ozdamar B | display-authors=3 | last4=Bose | first4=R | last5=Liu | first5=Z | last6=Donovan | first6=RS | last7=Shinjo | first7=F | last8=Liu | first8=Y | last9=Dembowy | first9=J }} | *{{cite journal | author=Barrios-Rodiles M |title=High-throughput mapping of a dynamic signaling network in mammalian cells |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 |name-list-format=vanc| author2=Brown KR | author3=Ozdamar B | display-authors=3 | last4=Bose | first4=R | last5=Liu | first5=Z | last6=Donovan | first6=RS | last7=Shinjo | first7=F | last8=Liu | first8=Y | last9=Dembowy | first9=J }} | ||
*{{cite journal |vauthors=Eastwood SL, Burnet PW, Harrison PJ |title=Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia |journal=Biol. Psychiatry |volume=57 |issue= 7 |pages= 702–10 |year= 2005 |pmid= 15820226 |doi= 10.1016/j.biopsych.2004.12.029 }} | *{{cite journal |vauthors=Eastwood SL, Burnet PW, Harrison PJ |title=Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia |journal=Biol. Psychiatry |volume=57 |issue= 7 |pages= 702–10 |year= 2005 |pmid= 15820226 |doi= 10.1016/j.biopsych.2004.12.029 }} | ||
*{{cite journal | author=Kinoshita Y |title=No association with the calcineurin A gamma subunit gene (PPP3CC) haplotype to Japanese schizophrenia |journal=Journal of | *{{cite journal | author=Kinoshita Y |title=No association with the calcineurin A gamma subunit gene (PPP3CC) haplotype to Japanese schizophrenia |journal=Journal of Neural Transmission |volume=112 |issue= 9 |pages= 1255–62 |year= 2006 |pmid= 15843870 |doi= 10.1007/s00702-004-0261-5 |name-list-format=vanc| author2=Suzuki T | author3=Ikeda M | display-authors=3 | last4=Kitajima | first4=T. | last5=Yamanouchi | first5=Y. | last6=Inada | first6=T. | last7=Yoneda | first7=H. | last8=Iwata | first8=N. | last9=Ozaki | first9=N. }} | ||
*{{cite journal | author=Liu YL |title=More evidence supports the association of PPP3CC with schizophrenia |journal=Mol. Psychiatry |volume=12 |issue= 10 |pages= 966–74 |year= 2008 |pmid= 17339875 |doi= 10.1038/sj.mp.4001977 |name-list-format=vanc| author2=Fann CS | author3=Liu CM | display-authors=3 | last4=Chang | first4=C C | last5=Yang | first5=W C | last6=Hung | first6=S I | last7=Yu | first7=S L | last8=Hwang | first8=T J | last9=Hsieh | first9=M H }} | *{{cite journal | author=Liu YL |title=More evidence supports the association of PPP3CC with schizophrenia |journal=Mol. Psychiatry |volume=12 |issue= 10 |pages= 966–74 |year= 2008 |pmid= 17339875 |doi= 10.1038/sj.mp.4001977 |name-list-format=vanc| author2=Fann CS | author3=Liu CM | display-authors=3 | last4=Chang | first4=C C | last5=Yang | first5=W C | last6=Hung | first6=S I | last7=Yu | first7=S L | last8=Hwang | first8=T J | last9=Hsieh | first9=M H }} | ||
*{{cite journal | author=Horiuchi Y |title=Support for association of the PPP3CC gene with schizophrenia |journal=Mol. Psychiatry |volume=12 |issue= 10 |pages= 891–3 |year= 2008 |pmid= 17895921 |doi= 10.1038/sj.mp.4002019 |name-list-format=vanc| author2=Ishiguro H | author3=Koga M | display-authors=3 | last4=Inada | first4=T | last5=Iwata | first5=N | last6=Ozaki | first6=N | last7=Ujike | first7=H | last8=Muratake | first8=T | last9=Someya | first9=T }} | *{{cite journal | author=Horiuchi Y |title=Support for association of the PPP3CC gene with schizophrenia |journal=Mol. Psychiatry |volume=12 |issue= 10 |pages= 891–3 |year= 2008 |pmid= 17895921 |doi= 10.1038/sj.mp.4002019 |name-list-format=vanc| author2=Ishiguro H | author3=Koga M | display-authors=3 | last4=Inada | first4=T | last5=Iwata | first5=N | last6=Ozaki | first6=N | last7=Ujike | first7=H | last8=Muratake | first8=T | last9=Someya | first9=T }} | ||
Revision as of 16:53, 6 December 2018
This article needs more links to other articles to help integrate it into the encyclopedia. (September 2017) (Learn how and when to remove this template message) |
| VALUE_ERROR (nil) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Aliases | |||||||
| External IDs | GeneCards: [1] | ||||||
| Orthologs | |||||||
| Species | Human | Mouse | |||||
| Entrez |
|
| |||||
| Ensembl |
|
| |||||
| UniProt |
|
| |||||
| RefSeq (mRNA) |
|
| |||||
| RefSeq (protein) |
|
| |||||
| Location (UCSC) | n/a | n/a | |||||
| PubMed search | n/a | n/a | |||||
| Wikidata | |||||||
| |||||||
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PP2BC) is an enzyme that in humans is encoded by the PPP3CC gene.[1][2]
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM][2]
References
- ↑ Muramatsu T, Kincaid RL (Nov 1992). "Molecular cloning and chromosomal mapping of the human gene for the testis-specific catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin A)". Biochem Biophys Res Commun. 188 (1): 265–71. doi:10.1016/0006-291X(92)92379-C. PMID 1339277.
- ↑ 2.0 2.1 "Entrez Gene: PPP3CC protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform".
Further reading
- Esau C, Boes M, Youn HD, et al. (2001). "Deletion of Calcineurin and Myocyte Enhancer Factor 2 (MEF2) Binding Domain of Cabin1 Results in Enhanced Cytokine Gene Expression in T Cells". J. Exp. Med. 194 (10): 1449–59. doi:10.1084/jem.194.10.1449. PMC 2193671. PMID 11714752.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Bennasser Y, Badou A, Tkaczuk J, Bahraoui E (2003). "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha". Virology. 303 (1): 174–80. doi:10.1006/viro.2002.1676. PMID 12482669.
- Gerber DJ, Hall D, Miyakawa T, et al. (2003). "Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit". Proc. Natl. Acad. Sci. U.S.A. 100 (15): 8993–8. doi:10.1073/pnas.1432927100. PMC 166426. PMID 12851458.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
- Eastwood SL, Burnet PW, Harrison PJ (2005). "Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia". Biol. Psychiatry. 57 (7): 702–10. doi:10.1016/j.biopsych.2004.12.029. PMID 15820226.
- Kinoshita Y, Suzuki T, Ikeda M, et al. (2006). "No association with the calcineurin A gamma subunit gene (PPP3CC) haplotype to Japanese schizophrenia". Journal of Neural Transmission. 112 (9): 1255–62. doi:10.1007/s00702-004-0261-5. PMID 15843870.
- Liu YL, Fann CS, Liu CM, et al. (2008). "More evidence supports the association of PPP3CC with schizophrenia". Mol. Psychiatry. 12 (10): 966–74. doi:10.1038/sj.mp.4001977. PMID 17339875.
- Horiuchi Y, Ishiguro H, Koga M, et al. (2008). "Support for association of the PPP3CC gene with schizophrenia". Mol. Psychiatry. 12 (10): 891–3. doi:10.1038/sj.mp.4002019. PMID 17895921.
 | This article on a gene on human chromosome 8 is a stub. You can help Wikipedia by expanding it. |
Categories:
- Pages with broken file links
- Articles with too few wikilinks from September 2017
- Articles with invalid date parameter in template
- All articles with too few wikilinks
- Articles covered by WikiProject Wikify from September 2017
- All articles covered by WikiProject Wikify
- Genes on human chromosome
- All stub articles
- Human chromosome 8 gene stubs