IGBP1: Difference between revisions

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m (→‎Further reading: task, replaced: International Journal of Cancer. Journal International Du Cancer → International Journal of Cancer using AWB)
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* {{cite journal | vauthors = Chung H, Nairn AC, Murata K, Brautigan DL | title = Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2 | journal = Biochemistry | volume = 38 | issue = 32 | pages = 10371–6 | date = Aug 1999 | pmid = 10441131 | doi = 10.1021/bi990902g }}
* {{cite journal | vauthors = Chung H, Nairn AC, Murata K, Brautigan DL | title = Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2 | journal = Biochemistry | volume = 38 | issue = 32 | pages = 10371–6 | date = Aug 1999 | pmid = 10441131 | doi = 10.1021/bi990902g }}
* {{cite journal | vauthors = Scanlan MJ, Gordan JD, Williamson B, Stockert E, Bander NH, Jongeneel V, Gure AO, Jäger D, Jäger E, Knuth A, Chen YT, Old LJ | title = Antigens recognized by autologous antibody in patients with renal-cell carcinoma | journal = International Journal of Cancer | volume = 83 | issue = 4 | pages = 456–64 | date = Nov 1999 | pmid = 10508479 | doi = 10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 }}
* {{cite journal | vauthors = Scanlan MJ, Gordan JD, Williamson B, Stockert E, Bander NH, Jongeneel V, Gure AO, Jäger D, Jäger E, Knuth A, Chen YT, Old LJ | title = Antigens recognized by autologous antibody in patients with renal-cell carcinoma | journal = International Journal of Cancer | volume = 83 | issue = 4 | pages = 456–64 | date = Nov 1999 | pmid = 10508479 | doi = 10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 }}
* {{cite journal | vauthors = Liu J, Prickett TD, Elliott E, Meroni G, Brautigan DL | title = Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 98 | issue = 12 | pages = 6650–5 | date = Jun 2001 | pmid = 11371618 | pmc = 34408 | doi = 10.1073/pnas.111154698 }}
* {{cite journal | vauthors = Liu J, Prickett TD, Elliott E, Meroni G, Brautigan DL | title = Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 98 | issue = 12 | pages = 6650–5 | date = Jun 2001 | pmid = 11371618 | pmc = 34408 | doi = 10.1073/pnas.111154698 | bibcode = 2001PNAS...98.6650L }}
* {{cite journal | vauthors = Short KM, Hopwood B, Yi Z, Cox TC | title = MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders | journal = BMC Cell Biology | volume = 3 | pages = 1 | year = 2002 | pmid = 11806752 | pmc = 64779 | doi = 10.1186/1471-2121-3-1 }}
* {{cite journal | vauthors = Short KM, Hopwood B, Yi Z, Cox TC | title = MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders | journal = BMC Cell Biology | volume = 3 | pages = 1 | year = 2002 | pmid = 11806752 | pmc = 64779 | doi = 10.1186/1471-2121-3-1 }}
* {{cite journal | vauthors = Graham JM, Wheeler P, Tackels-Horne D, Lin AE, Hall BD, May M, Short KM, Schwartz CE, Cox TC | title = A new X-linked syndrome with agenesis of the corpus callosum, mental retardation, coloboma, micrognathia, and a mutation in the Alpha 4 gene at Xq13 | journal = American Journal of Medical Genetics Part A | volume = 123A | issue = 1 | pages = 37–44 | date = Nov 2003 | pmid = 14556245 | doi = 10.1002/ajmg.a.20504 }}
* {{cite journal | vauthors = Graham JM, Wheeler P, Tackels-Horne D, Lin AE, Hall BD, May M, Short KM, Schwartz CE, Cox TC | title = A new X-linked syndrome with agenesis of the corpus callosum, mental retardation, coloboma, micrognathia, and a mutation in the Alpha 4 gene at Xq13 | journal = American Journal of Medical Genetics Part A | volume = 123A | issue = 1 | pages = 37–44 | date = Nov 2003 | pmid = 14556245 | doi = 10.1002/ajmg.a.20504 }}

Latest revision as of 23:08, 3 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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n/a

RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Immunoglobulin-binding protein 1 is a protein that in humans is encoded by the IGBP1 gene.[1][2]

Function

The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.[2]

Interactions

IGBP1 has been shown to interact with PPP4C,[3][4][5] PPP6C[4][5] and PPP2CA.[4][5][6][7]

References

  1. Onda M, Inui S, Maeda K, Suzuki M, Takahashi E, Sakaguchi N (Dec 1997). "Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway". Genomics. 46 (3): 373–8. doi:10.1006/geno.1997.5048. PMID 9441740.
  2. 2.0 2.1 "Entrez Gene: IGBP1 immunoglobulin (CD79A) binding protein 1".
  3. Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC (Oct 2008). "PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4". The Journal of Biological Chemistry. 283 (43): 29273–84. doi:10.1074/jbc.M803443200. PMC 2662017. PMID 18715871.
  4. 4.0 4.1 4.2 Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R (Nov 2005). "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity". Molecular & Cellular Proteomics. 4 (11): 1725–40. doi:10.1074/mcp.M500231-MCP200. PMID 16085932.
  5. 5.0 5.1 5.2 Chen J, Peterson RT, Schreiber SL (Jun 1998). "Alpha 4 associates with protein phosphatases 2A, 4, and 6". Biochemical and Biophysical Research Communications. 247 (3): 827–32. doi:10.1006/bbrc.1998.8792. PMID 9647778.
  6. Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Molecular & Cellular Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.
  7. Chung H, Nairn AC, Murata K, Brautigan DL (Aug 1999). "Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2". Biochemistry. 38 (32): 10371–6. doi:10.1021/bi990902g. PMID 10441131.

Further reading