Non-alcoholic fatty liver disease classification: Difference between revisions
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==Classification== | ==Classification== | ||
Non-alcoholic fatty liver disease may be classified based on clinical presentation into non-alcoholic fatty liver and non-alcoholic steatohepatitis.<ref name="pmid24661406">{{cite journal| author=Hashimoto E, Tokushige K, Ludwig J| title=Diagnosis and classification of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Current concepts and remaining challenges. | journal=Hepatol Res | year= 2015 | volume= 45 | issue= 1 | pages= 20-8 | pmid=24661406 | doi=10.1111/hepr.12333 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24661406 }} </ref><ref name="pmid28303724">{{cite journal| author=Cobbina E, Akhlaghi F| title=Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. | journal=Drug Metab Rev | year= 2017 | volume= 49 | issue= 2 | pages= 197-211 | pmid=28303724 | doi=10.1080/03602532.2017.1293683 | pmc=5576152 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28303724 }} </ref><ref name="pmid25763333">{{cite journal| author=Monteiro JM, Monteiro GM, Caroli-Bottino A, Pannain VL| title=Nonalcoholic fatty liver disease: different classifications concordance and relationship between degrees of morphological features and spectrum of the disease. | journal=Anal Cell Pathol (Amst) | year= 2014 | volume= 2014 | issue= | pages= 526979 | pmid=25763333 | doi=10.1155/2014/526979 | pmc=4333905 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25763333 }} </ref> | Non-alcoholic fatty liver disease may be classified based on clinical presentation into non-alcoholic fatty liver and non-alcoholic steatohepatitis.<ref name="pmid24661406">{{cite journal| author=Hashimoto E, Tokushige K, Ludwig J| title=Diagnosis and classification of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Current concepts and remaining challenges. | journal=Hepatol Res | year= 2015 | volume= 45 | issue= 1 | pages= 20-8 | pmid=24661406 | doi=10.1111/hepr.12333 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24661406 }} </ref><ref name="pmid28303724">{{cite journal| author=Cobbina E, Akhlaghi F| title=Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. | journal=Drug Metab Rev | year= 2017 | volume= 49 | issue= 2 | pages= 197-211 | pmid=28303724 | doi=10.1080/03602532.2017.1293683 | pmc=5576152 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28303724 }} </ref><ref name="pmid25763333">{{cite journal| author=Monteiro JM, Monteiro GM, Caroli-Bottino A, Pannain VL| title=Nonalcoholic fatty liver disease: different classifications concordance and relationship between degrees of morphological features and spectrum of the disease. | journal=Anal Cell Pathol (Amst) | year= 2014 | volume= 2014 | issue= | pages= 526979 | pmid=25763333 | doi=10.1155/2014/526979 | pmc=4333905 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25763333 }} </ref> | ||
{|border="1" cellpadding="5" cellspacing="0" align="center" |class="wikitable" | {| border="1" cellpadding="5" cellspacing="0" align="center" |class="wikitable" | ||
! colspan="2" | ! colspan="2" style="background:#efefef;" |Based on clinical presentation | ||
|- | |- | ||
! style="background:#efefef;" |Non-alcoholic fatty aliver | ! style="background:#efefef;" |Non-alcoholic fatty aliver | ||
! style="background:#efefef;" |Non-alcoholic steatohepatitis | ! style="background:#efefef;" |Non-alcoholic steatohepatitis | ||
|- | |- | ||
|Benign | | | ||
|Aggressive | * Benign | ||
| | |||
* Aggressive | |||
|- | |- | ||
|Non-progressive | | | ||
|Can progress to cirrhosis | * Non-progressive | ||
| | |||
* Can progress to cirrhosis | |||
* Rarely can give rise to hepatocellular carcinoma | |||
|- | |- | ||
! colspan="2" | ! colspan="2" style="background:#efefef;" |Based on histopathology | ||
|- | |- | ||
| colspan="2" | | | colspan="2" | | ||
Revision as of 16:57, 21 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Clinically non-alcoholic fatty liver disease may be classified into non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH).
Classification
Non-alcoholic fatty liver disease may be classified based on clinical presentation into non-alcoholic fatty liver and non-alcoholic steatohepatitis.[1][2][3]
| Based on clinical presentation | |
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| Non-alcoholic fatty aliver | Non-alcoholic steatohepatitis |
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| Based on histopathology | |
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References
- ↑ Hashimoto E, Tokushige K, Ludwig J (2015). "Diagnosis and classification of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Current concepts and remaining challenges". Hepatol Res. 45 (1): 20–8. doi:10.1111/hepr.12333. PMID 24661406.
- ↑ Cobbina E, Akhlaghi F (2017). "Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters". Drug Metab Rev. 49 (2): 197–211. doi:10.1080/03602532.2017.1293683. PMC 5576152. PMID 28303724.
- ↑ Monteiro JM, Monteiro GM, Caroli-Bottino A, Pannain VL (2014). "Nonalcoholic fatty liver disease: different classifications concordance and relationship between degrees of morphological features and spectrum of the disease". Anal Cell Pathol (Amst). 2014: 526979. doi:10.1155/2014/526979. PMC 4333905. PMID 25763333.