Hepatic encephalopathy primary prevention: Difference between revisions
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==Primary Prevention== | ==Primary Prevention== | ||
Usage of [[lactulose]] is helpful in prevention of HE in patients with [[cirrhosis]] and acute [[variceal bleeding]].<ref name="pmid21129028">{{cite journal| author=Sharma P, Agrawal A, Sharma BC, Sarin SK| title=Prophylaxis of hepatic encephalopathy in acute variceal bleed: a randomized controlled trial of lactulose versus no lactulose. | journal=J Gastroenterol Hepatol | year= 2011 | volume= 26 | issue= 6 | pages= 996-1003 | pmid=21129028 | doi=10.1111/j.1440-1746.2010.06596.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21129028 }} </ref> | *Usage of [[lactulose]] is helpful in prevention of HE in patients with [[cirrhosis]] and acute [[variceal bleeding]].<ref name="pmid21129028">{{cite journal| author=Sharma P, Agrawal A, Sharma BC, Sarin SK| title=Prophylaxis of hepatic encephalopathy in acute variceal bleed: a randomized controlled trial of lactulose versus no lactulose. | journal=J Gastroenterol Hepatol | year= 2011 | volume= 26 | issue= 6 | pages= 996-1003 | pmid=21129028 | doi=10.1111/j.1440-1746.2010.06596.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21129028 }} </ref> | ||
*Lactulose may be effective to prevent of recurrence of hepatic encephalopathy in patients with cirrhosis.<ref name="pmid19501587">{{cite journal| author=Sharma BC, Sharma P, Agrawal A, Sarin SK| title=Secondary prophylaxis of hepatic encephalopathy: an open-label randomized controlled trial of lactulose versus placebo. | journal=Gastroenterology | year= 2009 | volume= 137 | issue= 3 | pages= 885-91, 891.e1 | pmid=19501587 | doi=10.1053/j.gastro.2009.05.056 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19501587 }} </ref> | |||
Usage of lactitol or rifaximin is not effective in the prophylaxis of hepatic encephalopathy during the first month after a transjugular-intrahepatic-portosystemic-shunt (TIPS). | *Usage of lactitol or rifaximin is not effective in the prophylaxis of hepatic encephalopathy during the first month after a transjugular-intrahepatic-portosystemic-shunt (TIPS).<ref name="pmid15826716">{{cite journal| author=Riggio O, Masini A, Efrati C, Nicolao F, Angeloni S, Salvatori FM et al.| title=Pharmacological prophylaxis of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt: a randomized controlled study. | journal=J Hepatol | year= 2005 | volume= 42 | issue= 5 | pages= 674-9 | pmid=15826716 | doi=10.1016/j.jhep.2004.12.028 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15826716 }} </ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Primary Prevention
- Usage of lactulose is helpful in prevention of HE in patients with cirrhosis and acute variceal bleeding.[1]
- Lactulose may be effective to prevent of recurrence of hepatic encephalopathy in patients with cirrhosis.[2]
- Usage of lactitol or rifaximin is not effective in the prophylaxis of hepatic encephalopathy during the first month after a transjugular-intrahepatic-portosystemic-shunt (TIPS).[3]
References
- ↑ Sharma P, Agrawal A, Sharma BC, Sarin SK (2011). "Prophylaxis of hepatic encephalopathy in acute variceal bleed: a randomized controlled trial of lactulose versus no lactulose". J Gastroenterol Hepatol. 26 (6): 996–1003. doi:10.1111/j.1440-1746.2010.06596.x. PMID 21129028.
- ↑ Sharma BC, Sharma P, Agrawal A, Sarin SK (2009). "Secondary prophylaxis of hepatic encephalopathy: an open-label randomized controlled trial of lactulose versus placebo". Gastroenterology. 137 (3): 885–91, 891.e1. doi:10.1053/j.gastro.2009.05.056. PMID 19501587.
- ↑ Riggio O, Masini A, Efrati C, Nicolao F, Angeloni S, Salvatori FM; et al. (2005). "Pharmacological prophylaxis of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt: a randomized controlled study". J Hepatol. 42 (5): 674–9. doi:10.1016/j.jhep.2004.12.028. PMID 15826716.