Polycythemia vera classification: Difference between revisions
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{{Polycythemia vera}} | {{Polycythemia vera}} | ||
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==Overview== | ==Overview== | ||
Polycythemia vera is a subtype of [[myeloproliferative neoplasm]]. [[Myeloproliferative neoplasm]] may be classified according to the World Health Organization into eight subtypes: [[chronic myelogenous leukemia]], [[chronic neutrophilic leukemia]], [[polycythemia vera]], [[primary myelofibrosis]], [[essential thrombocythemia]], [[chronic eosinophilic leukemia]], [[mastocytosis]], and myeloproliferative neoplasms, unclassifiable.<ref name="pmid19357394">{{cite journal| author=Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A et al.| title=The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. | journal=Blood | year= 2009 | volume= 114 | issue= 5 | pages= 937-51 | pmid=19357394 | doi=10.1182/blood-2009-03-209262 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19357394 }} </ref> | Polycythemia vera is a subtype of [[myeloproliferative neoplasm]]. [[Myeloproliferative neoplasm]] may be classified according to the World Health Organization into eight subtypes: [[chronic myelogenous leukemia]], [[chronic neutrophilic leukemia]], [[polycythemia vera]], [[primary myelofibrosis]], [[essential thrombocythemia]], [[chronic eosinophilic leukemia]], [[mastocytosis]], and myeloproliferative neoplasms, unclassifiable.<ref name="pmid19357394">{{cite journal| author=Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A et al.| title=The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. | journal=Blood | year= 2009 | volume= 114 | issue= 5 | pages= 937-51 | pmid=19357394 | doi=10.1182/blood-2009-03-209262 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19357394 }} </ref> | ||
Revision as of 23:45, 28 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3]
Overview
Polycythemia vera is a subtype of myeloproliferative neoplasm. Myeloproliferative neoplasm may be classified according to the World Health Organization into eight subtypes: chronic myelogenous leukemia, chronic neutrophilic leukemia, polycythemia vera, primary myelofibrosis, essential thrombocythemia, chronic eosinophilic leukemia, mastocytosis, and myeloproliferative neoplasms, unclassifiable.[1]
Classification
Classification of myeloproliferative neoplasms
Polycythemia vera is a subtype of myeloproliferative neoplasm. Myeloproliferative neoplasm may be classified according to the World Health Organization into eight subtypes:[1][2]
- Polycythemia vera
- Essential thrombocythemia
- Chronic myelogenous leukemia, BCR-ABL1–positive
- Chronic myelogenous leukemia, BCR-ABL1–negative (atypical CML)
- Chronic neutrophilic leukemia
- Primary myelofibrosis
- Chronic eosinophilic leukemia, not otherwise specified
- Mastocytosis
- Myeloproliferative neoplasms, unclassifiable
There are no subcategories within polycythemia vera.
Classification of polycythemia
Polycythemia vera is a subcategory of polycythemia in general. Classification of polycythemia in general includes primary polycythemia and secondary polycythemia. Secondary polycythemia is due to chronic hypoxia which results in compensatory increase in erythrocyte production. Secondary polycythemia is therefore characterized by a reactive increase in erythrocyte production, rather than clonal proliferation of erythrocytes.
- Primary polycythemia (polycythemia vera)
- Secondary polycythemia
- Congestive heart failure
- Chronic obstructive pulmonary disease
- Interstitial lung disease
- Smoking
- Obstructive sleep apnea
- High altitude residence
- Erythropoietin-secreting tumors
- Renal cell carcinoma
- Hepatocellular carcinoma
References
- ↑ 1.0 1.1 Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A; et al. (2009). "The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes". Blood. 114 (5): 937–51. doi:10.1182/blood-2009-03-209262. PMID 19357394.
- ↑ Valent P, Horny HP, Escribano L, Longley BJ, Li CY, Schwartz LB; et al. (2001). "Diagnostic criteria and classification of mastocytosis: a consensus proposal". Leuk Res. 25 (7): 603–25. PMID 11377686.