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===Incidence=== | ===Incidence=== | ||
*The incidence of cholangiocarcinoma is approximately 1-2 per 100,000 individuals in the United States. | *The incidence of cholangiocarcinoma is approximately 1-2 per 100,000 individuals in the United States. | ||
*The highest annual incidences of cholangiocarcinoma is 5.5 cases per 100,000 people in Japan, and 7.3 cases per 100,000 people in Israel. | *The highest annual incidences of cholangiocarcinoma is 5.5 cases per 100,000 people in Japan, and 7.3 cases per 100,000 people in Israel.<ref name="pmid18773060">{{cite journal |vauthors=Khan SA, Toledano MB, Taylor-Robinson SD |title=Epidemiology, risk factors, and pathogenesis of cholangiocarcinoma |journal=HPB (Oxford) |volume=10 |issue=2 |pages=77–82 |year=2008 |pmid=18773060 |pmc=2504381 |doi=10.1080/13651820801992641 |url=}}</ref> | ||
===Prevalence=== | ===Prevalence=== | ||
Revision as of 15:53, 29 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2] Suveenkrishna Pothuru, M.B,B.S. [3]
Overview
Epidemiology and Demographics
Incidence
- The incidence of cholangiocarcinoma is approximately 1-2 per 100,000 individuals in the United States.
- The highest annual incidences of cholangiocarcinoma is 5.5 cases per 100,000 people in Japan, and 7.3 cases per 100,000 people in Israel.[1]
Prevalence
- The prevalence of cholangiocarcinoma is approximately 0.01% to 0.46% per 100,000 individuals.
- The prevalence of cholangiocarcinoma in patients with primary sclerosing cholangitis may be as high as 30%, based on autopsy studies.
Case-fatality rate/Mortality rate
- The mortality rate for intrahepatic cholangiocarcinoma among men increased from 0.17 to 0.78 per 100,000 in period of 1975-1979 to 1993-1997.
- The mortality rate for intrahepatic cholangiocarcinoma among women women increased from 0.12 to 0.57 per 100,000 in period of 1975-1979 to 1993-1997.
Age
- Patients of all age groups may develop cholangiocarcinoma.
- The median age at the time of cholangiocarcinoma diagnosis is 70-80 years, except in patients with bile duct cystic disorders.
- Bile duct cystic disorders usually develop cholangiocarcinoma much earlier, between 30 and 40 years.
Race
- Cholangiocarcinoma usually affects individuals of the American Indian, Alaska Natives and Asian and Pacific Islanders race.
Gender
- Cholangiocarcinoma is more common in males than in females.).[2]
Region
- The majority of cholangiocarcinoma cases are reported in North America, Asia, and Australia.[3]
References
- ↑ Khan SA, Toledano MB, Taylor-Robinson SD (2008). "Epidemiology, risk factors, and pathogenesis of cholangiocarcinoma". HPB (Oxford). 10 (2): 77–82. doi:10.1080/13651820801992641. PMC 2504381. PMID 18773060.
- ↑ Cholangiocarcinoma. Radiopaedia. http://radiopaedia.org/articles/cholangiocarcinoma
- ↑ McLean L, Patel T (2006). "Racial and ethnic variations in the epidemiology of intrahepatic cholangiocarcinoma in the United States". Liver Int. 26 (9): 1047–53. doi:10.1111/j.1478-3231.2006.01350.x. PMID 17032404.