Gallbladder cancer differential diagnosis: Difference between revisions
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** [[Cirrhosis]] | ** [[Cirrhosis]] | ||
** [[Inflammatory]] [[lesions]] | ** [[Inflammatory]] [[lesions]] | ||
** [[Cholangiocarcinoma]]<ref>{{cite journal|doi=10. | ** [[Cholangiocarcinoma]]<ref name="WilsonKim2007">{{cite journal|last1=Wilson|first1=Stephanie R.|last2=Kim|first2=Tae Kyoung|last3=Jang|first3=Hyun-Jung|last4=Burns|first4=Peter N.|title=Enhancement Patterns of Focal Liver Masses: Discordance Between Contrast-Enhanced Sonography and Contrast-Enhanced CT and MRI|journal=American Journal of Roentgenology|volume=189|issue=1|year=2007|pages=W7–W12|issn=0361-803X|doi=10.2214/AJR.06.1060}}</ref> | ||
** [[Pancreatic carcinoma]] | ** [[Pancreatic carcinoma]] | ||
** [[Focal nodular hyperplasia]] | ** [[Focal nodular hyperplasia]] | ||
Revision as of 16:44, 31 January 2018
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Gallbladder cancer Microchapters |
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Diagnosis |
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Case Studies |
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Gallbladder cancer differential diagnosis On the Web |
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American Roentgen Ray Society Images of Gallbladder cancer differential diagnosis |
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Risk calculators and risk factors for Gallbladder cancer differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Gallbladder cancer must be differentiated from Hepatocellular carcinoma Liver hemangioma, Liver abscess, Cirrhosis, Inflammatory lesions, Cholangiocarcinoma, Pancreatic carcinoma,Focal nodular hyperplasia.
Differentiatiating Gallbladder cancer from other Diseases
- Gallbladder cancer must be differentiated from other diseases that causes right upper quadrant pain
Abbreviations: RUQ= Right upper quadrant of the abdomen, LUQ= Left upper quadrant, LLQ= Left lower quadrant, RLQ= Right lower quadrant, LFT= Liver function test, SIRS= Systemic inflammatory response syndrome, ERCP= Endoscopic retrograde cholangiopancreatography, IV= Intravenous, N= Normal, AMA= Anti mitochondrial antibodies, LDH= Lactate dehydrogenase, GI= Gastrointestinal, CXR= Chest X ray, IgA= Immunoglobulin A, IgG= Immunoglobulin G, IgM= Immunoglobulin M, CT= Computed tomography, PMN= Polymorphonuclear cells, ESR= Erythrocyte sedimentation rate, CRP= C-reactive protein, TS= Transferrin saturation, SF= Serum Ferritin, SMA= Superior mesenteric artery, SMV= Superior mesenteric vein, ECG= Electrocardiogram
| Disease | Clinical manifestations | Diagnosis | Comments | |||||||||||||
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| Symptoms | Signs | |||||||||||||||
| Abdominal Pain | Fever | Rigors and chills | Nausea or vomiting | Jaundice | Constipation | Diarrhea | Weight loss | GI bleeding | Hypo-
tension |
Guarding | Rebound Tenderness | Bowel sounds | Lab Findings | Imaging | ||
| Hepatocellular carcinoma/Metastasis | RUQ | + | − | − | + | − | − | + | − | − | − | − |
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Other symptoms: |
| Cholangiocarcinoma | Epigastric | − | − | ± | ± | − | + | + | − | − | − | − | N | CT scan
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| Pancreatic carcinoma | Epigastric | − | − | + | + | − | + | + | − | − | − | − | N |
Skin manifestations may include: | ||
| Focal nodular hyperplasia | Diffuse | ± | − | − | ± | − | + | + | + | − | − | − | Normal or hyperactive |
Extra intestinal findings: | ||
| Disease | Abdominal Pain | Fever | Rigors and chills | Nausea or vomiting | Jaundice | Constipation | Diarrhea | Weight loss | GI bleeding | Hypo-
tension |
Guarding | Rebound Tenderness | Bowel sounds | Lab Findings | Imaging | Comments |
| Gallbladder cancer | Diffuse | ± | − | − | ± | − | + | + | − | ± | − | − | N | Endoscopy is used to confirm diagnosis.
Images used to find complications |
Extra intestinal findings: | |
| Liver hemangioma | RUQ | + | − | + | + | − | Positive in Hep A and E | + | − | Positive in fulminant hepatitis | Positive in acute | + | N |
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| Liver abscess | RUQ | + | + | + | + | − | ± | + | − | + | + | ± | Normal or hypoactive |
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| Cirrhosis | RUQ | − | − | − | + | − | − | + | + | + | − | − | N |
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US
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| Inflammatory lesions | RUQ | − | − | − | + | − | − | + | + | + | − | − | N |
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US
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References
- ↑ Wilson, Stephanie R.; Kim, Tae Kyoung; Jang, Hyun-Jung; Burns, Peter N. (2007). "Enhancement Patterns of Focal Liver Masses: Discordance Between Contrast-Enhanced Sonography and Contrast-Enhanced CT and MRI". American Journal of Roentgenology. 189 (1): W7–W12. doi:10.2214/AJR.06.1060. ISSN 0361-803X.