Jaundice history & symptoms: Difference between revisions
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*** [[Weight loss]] | *** [[Weight loss]] | ||
* '''Pancreatic cancer''' | * '''Pancreatic cancer''' | ||
** | ** [[Weight loss|Weight Loss]] (significant) | ||
** | ** [[Jaundice]] | ||
** | ** [[Epigastric|Midepigastric]] [[pain]] which may also radiate either to the lower back region and mid-back region | ||
** [[ | ** [[Nausea]] | ||
** [[Acholic stools| | ** [[Vomiting]] | ||
** [[Malaise]] | |||
** [[Fatigue]] | |||
** [[Anorexia|Loss of appetite]] | |||
** [[Anorexia]] | |||
** [[Dyspepsia]] | |||
** [[Ascites]] | |||
** Dark [[urine]] | |||
** [[Acholic stools|Light-colored or greasy stools]] | |||
==References== | ==References== |
Revision as of 19:03, 1 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Farnaz Khalighinejad, MD [2]
Overview
Common symptoms of jaundice that the patient will notice, is yellowing of the skin, nausea, and vomiting. Specific symptoms will depend on the underlying factor that caused jaundice to occur.
History and Symptoms
Jaundice typically appears in a 'top to bottom' progression (starting with the face, progressing toward the feet), and resolves in a 'bottom to top' manner.
The caregiver should ask questions regarding
- Alcohol/hepatotoxic medication use
Various Symptoms
- Cirrhosis
The symptoms of liver cirrhosis are very non-specific:[3] [4]
Right upper quadrant abdominal pain
- Fever
- Anorexia
- Fatigue and weakness
- Nausea and vomiting
- Weight loss
- Abdominal pain and bloating
- Menstrual irregularities
- Symptoms of hypogonadism:
- Impotence
- Infertility
- Testicular atrophy
- Loss of libido
- Easy bruisability
- Decompensated cirrhosis may present with:[5]
- Jaundice
- Increase in abdominal girth due to ascites
- Pruritus
- Signs of upper gastrointestinal bleeding:
- Symptoms due to hepatic encephalopathy:
- Altered mental status
- Confusion
- Sleep disturbances
- Muscle cramps due to reduction in effective circulating plasma volume
- Lower extremity edema
- Symptoms may vary depending on the underlying cause of cirrhosis:
- Primary biliary cirrhosis presents with the following symptoms:
- Primary sclerosing cholangitis may present with the following in addition to the above symptoms of cirrhosis:
- Pancreatic cancer
- Weight Loss (significant)
- Jaundice
- Midepigastric pain which may also radiate either to the lower back region and mid-back region
- Nausea
- Vomiting
- Malaise
- Fatigue
- Loss of appetite
- Anorexia
- Dyspepsia
- Ascites
- Dark urine
- Light-colored or greasy stools
References
- ↑ Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH (2018). "ACG Clinical Guideline: Alcoholic Liver Disease". Am. J. Gastroenterol. doi:10.1038/ajg.2017.469. PMID 29336434.
- ↑ Krugman S, Giles JP (1970). "Viral hepatitis. New light on an old disease". JAMA. 212 (6): 1019–29. PMID 4191502.
- ↑ Williams EJ, Iredale JP (1998). "Liver cirrhosis". Postgrad Med J. 74 (870): 193–202. PMC 2360862. PMID 9683971.
- ↑ Schuppan D, Afdhal NH (2008). "Liver cirrhosis". Lancet. 371 (9615): 838–51. doi:10.1016/S0140-6736(08)60383-9. PMC 2271178. PMID 18328931.
- ↑ Bloom S, Kemp W, Lubel J (2015). "Portal hypertension: pathophysiology, diagnosis and management". Intern Med J. 45 (1): 16–26. doi:10.1111/imj.12590. PMID 25230084.