Barrett's esophagus natural history, complications and prognosis: Difference between revisions
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===Natural History=== | ===Natural History=== | ||
An increased risk of [[esophageal cancer]] is present. Follow-up [[endoscopy]] to look for [[dysplasia]] or [[cancer]] is often advised. | An increased risk of [[esophageal cancer]] is present. Follow-up [[endoscopy]] to look for [[dysplasia]] or [[cancer]] is often advised. | ||
*The symptoms of | *The symptoms of [[Barrett's esophagus]] usually develop in the fifth/sixth decade of life, and start with symptoms such as ___. | ||
*The symptoms of (disease name) typically develop ___ years after exposure to ___. | *The symptoms of (disease name) typically develop ___ years after exposure to ___. | ||
*If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3]. | *If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3]. | ||
Revision as of 15:06, 2 February 2018
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Barrett's Esophagus Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amresh Kumar MD [2]
Overview
Common complications of Barrett's esophagus include esophageal carcinoma[1], esophageal stricture and esophageal ulcers.
Natural History, Complications, and Prognosis
Natural History
An increased risk of esophageal cancer is present. Follow-up endoscopy to look for dysplasia or cancer is often advised.
- The symptoms of Barrett's esophagus usually develop in the fifth/sixth decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of Barrett's esophagus include:
Progression
- From low-grade dysplasia to high-grade dysplasia or esophageal adenocarcinoma: 0.5 to 13.4% per year
- From high-grade dysplasia to cancer: 6% per year.[2]
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Hvid-Jensen F, Pedersen L, Drewes AM, Sørensen HT, Funch-Jensen P (2011). "Incidence of adenocarcinoma among patients with Barrett's esophagus". N Engl J Med. 365 (15): 1375–83. doi:10.1056/NEJMoa1103042. PMID 21995385.
- ↑ Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). "American Gastroenterological Association medical position statement on the management of Barrett's esophagus". Gastroenterology. 140 (3): 1084–91. doi:10.1053/j.gastro.2011.01.030. PMID 21376940. Unknown parameter
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