Gastroparesis Diagnostic Study of Choice: Difference between revisions
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{{CMG}}; {{AE}} {{SSH}}; {{MSI}} | {{CMG}}; {{AE}} {{SSH}}; {{MSI}} | ||
== Overview == | == Overview == | ||
Gastric emptying scintigraphy is considered | [[Scintigraphy|Gastric emptying scintigraphy]] is considered a [[Gold standard (test)|gold standard]] diagnostic test for gastroparesis. [[Delayed gastric emptying]] is confirmed by 10% [[Stomach|gastric]] retention at 4 hours. Factors that affect the results of this test include [[Medication|medications]], [[tobacco smoking]], and [[hyperglycemia]]. | ||
== Diagnostic Study of Choice == | == Diagnostic Study of Choice == | ||
*[[Scintigraphy|Gastric emptying scintigraphy]] is considered a [[Gold standard (test)|gold standard]] diagnostic test for gastroparesis.<ref name="TangFriedenberg2011">{{cite journal|last1=Tang|first1=Derek M.|last2=Friedenberg|first2=Frank K.|title=Gastroparesis: Approach, Diagnostic Evaluation, and Management|journal=Disease-a-Month|volume=57|issue=2|year=2011|pages=74–101|issn=00115029|doi=10.1016/j.disamonth.2010.12.007}}</ref><ref name="KochCalles-Escandón2015">{{cite journal|last1=Koch|first1=Kenneth L.|last2=Calles-Escandón|first2=Jorge|title=Diabetic Gastroparesis|journal=Gastroenterology Clinics of North America|volume=44|issue=1|year=2015|pages=39–57|issn=08898553|doi=10.1016/j.gtc.2014.11.005}}</ref><ref name="pmid18028513">{{cite journal| author=Abell TL, Camilleri M, Donohoe K, Hasler WL, Lin HC, Maurer AH et al.| title=Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine. | journal=Am J Gastroenterol | year= 2008 | volume= 103 | issue= 3 | pages= 753-63 | pmid=18028513 | doi=10.1111/j.1572-0241.2007.01636.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18028513 }}</ref><ref name="pmid19115465">{{cite journal| author=Waseem S, Moshiree B, Draganov PV| title=Gastroparesis: current diagnostic challenges and management considerations. | journal=World J Gastroenterol | year= 2009 | volume= 15 | issue= 1 | pages= 25-37 | pmid=19115465 | doi= | pmc=2653292 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19115465 }}</ref> | |||
*Gastric emptying scintigraphy is considered | |||
*The method for this test is eating a low-fat, egg-white meal followed by repeated [[Scan|scans]] to measure the rate of [[gastric emptying]] at 0, 1, 2, and 4 hours. | *The method for this test is eating a low-fat, egg-white meal followed by repeated [[Scan|scans]] to measure the rate of [[gastric emptying]] at 0, 1, 2, and 4 hours. | ||
*The delayed gastric emptying would be confirmed, if there is: | *The delayed gastric emptying would be confirmed, if there is: | ||
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**10% [[Stomach|gastric]] retention at 4 hours (higher accuracy for detecting slow [[Stomach|gastric]] emptying) | **10% [[Stomach|gastric]] retention at 4 hours (higher accuracy for detecting slow [[Stomach|gastric]] emptying) | ||
*Factors that might affect on the results of [[Stomach|gastric]] emptying studies include: | *Factors that might affect on the results of [[Stomach|gastric]] emptying studies include: | ||
**[[Medication|Medications]] that slow down | **[[Medication|Medications]] that slow down gastric emptying include: | ||
***[[Anticholinergic|Anticholinergics]] | ***[[Anticholinergic|Anticholinergics]] | ||
***[[Tricyclic antidepressant|Tricyclic antidepressants]] | ***[[Tricyclic antidepressant|Tricyclic antidepressants]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]; Madhu Sigdel M.B.B.S.[3]
Overview
Gastric emptying scintigraphy is considered a gold standard diagnostic test for gastroparesis. Delayed gastric emptying is confirmed by 10% gastric retention at 4 hours. Factors that affect the results of this test include medications, tobacco smoking, and hyperglycemia.
Diagnostic Study of Choice
- Gastric emptying scintigraphy is considered a gold standard diagnostic test for gastroparesis.[1][2][3][4]
- The method for this test is eating a low-fat, egg-white meal followed by repeated scans to measure the rate of gastric emptying at 0, 1, 2, and 4 hours.
- The delayed gastric emptying would be confirmed, if there is:
- Factors that might affect on the results of gastric emptying studies include:
- Medications that slow down gastric emptying include:
- Tobacco smoking
- Hyperglycemia
- The advantages of gastric emptying scintigraphy include:
- Noninvasive
- Quantitative
- High sensitivity
- High specificity
References
- ↑ Tang, Derek M.; Friedenberg, Frank K. (2011). "Gastroparesis: Approach, Diagnostic Evaluation, and Management". Disease-a-Month. 57 (2): 74–101. doi:10.1016/j.disamonth.2010.12.007. ISSN 0011-5029.
- ↑ Koch, Kenneth L.; Calles-Escandón, Jorge (2015). "Diabetic Gastroparesis". Gastroenterology Clinics of North America. 44 (1): 39–57. doi:10.1016/j.gtc.2014.11.005. ISSN 0889-8553.
- ↑ Abell TL, Camilleri M, Donohoe K, Hasler WL, Lin HC, Maurer AH; et al. (2008). "Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine". Am J Gastroenterol. 103 (3): 753–63. doi:10.1111/j.1572-0241.2007.01636.x. PMID 18028513.
- ↑ Waseem S, Moshiree B, Draganov PV (2009). "Gastroparesis: current diagnostic challenges and management considerations". World J Gastroenterol. 15 (1): 25–37. PMC 2653292. PMID 19115465.