Occupational lung disease causes: Difference between revisions
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•Synthetic - fiber lung (Orlon, polyesters, nylon, acrylic) | •Synthetic - fiber lung (Orlon, polyesters, nylon, acrylic) | ||
•Bakelite worker's lung | •Bakelite worker's lung | ||
•[[Vinyl chloride]], polyvinyl chloride powder | |||
'''Gases''': | '''Gases''': | ||
| Line 103: | Line 103: | ||
•Oxides of nitrogen | •Oxides of nitrogen | ||
•[[Sulfur dioxide]] | |||
•Chlorine gas | •Chlorine gas | ||
| Line 111: | Line 111: | ||
'''Fumes''': | '''Fumes''': | ||
•Oxides of zinc, | •Oxides of [[zinc]], [[coppe]], [[manganese]], [[cadmium]], [[iron]], [[magnesium]], [[nickel]], [[brass]], [[selenium]], [[tin]], and [[antimony]] | ||
•[[Diphenylmethane diisocyanate]] | |||
•Trimellitic anhydride toxicity | •Trimellitic anhydride toxicity | ||
| Line 119: | Line 119: | ||
'''Vapors''': | '''Vapors''': | ||
•[[Hydrocarbons]] | |||
•Thermosetting resins (rubber tire workers) | •Thermosetting resins (rubber tire workers) | ||
•[[Toluene diisocyanate]] (TDI - asthmatic reactions prominent) | |||
•[[Oxygen]] | |||
•[[Mercury]] | |||
'''Aerosols''': | '''Aerosols''': | ||
| Line 159: | Line 159: | ||
|- bgcolor="LightSteelBlue" | |- bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
| bgcolor="Beige" | | | bgcolor="Beige" | •[[Farmer's lung ]](Macropolyspora faeni) | ||
•Grain handler's lung (Thermactinomyces vulgaris) | •Grain handler's lung (Thermactinomyces vulgaris) | ||
•Humidifier or air conditioner lung (T. sacchari) | •Humidifier or air conditioner lung (T. sacchari) | ||
• Aspergillus | • [[Aspergillus]] | ||
•Cryptostroma corticale | •Cryptostroma corticale | ||
•[[Aureobasidium pullulans]] | |||
•Penicillium species | •Penicillium species | ||
•[[Bacillus subtilis]] | |||
•[[B. cereus]] | |||
•Bird fancier's disease | •Bird fancier's disease | ||
| Line 260: | Line 260: | ||
| '''Miscellaneous''' | | '''Miscellaneous''' | ||
| bgcolor="Beige" | •Coal dust ("coal worker's pneumoconiosis") | | bgcolor="Beige" | •Coal dust ("coal worker's pneumoconiosis") | ||
•[[[Graphite]] ("carbon pneumoconiosis") | |||
•[[Tin]] ("stannosis") | |||
•[[Aluminum]] | |||
•Hard metal dusts (cadmium, tungsten, titanium and cobalt) | •Hard metal dusts ([[cadmium]], [[tungsten]], [[titanium]] and [[cobalt]]) | ||
•[[Iron]] ("siderosis") | |||
•[[Antimony]] | |||
•Hematite(mixed dusts of iron oxide, silica and silicates; "siderosilicosis") | •Hematite (mixed dusts of iron oxide, silica and silicates; "siderosilicosis") | ||
•Mixed dusts of silver and iron oxide ("argyrosiderosis") | •Mixed dusts of silver and iron oxide ("argyrosiderosis") | ||
•Copper sulfate neutralized with hydrated lime (Bordeaux mixture; "vineyard sprayer's lung") | |||
•Rare earths (cerium, scandium, yttrium, lanthanum) | •Rare earths (cerium, scandium, yttrium, lanthanum) | ||
| Line 285: | Line 285: | ||
{{columns-list|3| | {{columns-list|3| | ||
*Aluminum | *[[Aluminum]] | ||
*Aluminum silicates (sericite, sillimanite, zeolite) | *[[Aluminum]] silicates (sericite, sillimanite, zeolite) | ||
*Antimony | *[[Antimony]] | ||
*Asbestos ("asbestosis") | *[[Asbestos]] ("asbestosis") | ||
*Aspergillus | *[[Aspergillus]] | ||
*Aureobasidium pullulans | *[[Aureobasidium pullulans]] | ||
*B. cereus | *[[B. cereus]] | ||
*Bacillus subtilis | *[[Bacillus subtilis]] | ||
*Bakelite worker's lung | *Bakelite worker's lung | ||
*Beryllium ("berylliosis") | *[[Beryllium]] ("berylliosis") | ||
*Bird fancier's disease | *Bird fancier's disease | ||
*Chlorine gas | *[[Chlorine gas]] | ||
*Coal dust ("coal worker's pneumoconiosis") | *Coal dust ("coal worker's pneumoconiosis") | ||
*Cryptostroma corticale | *Cryptostroma corticale | ||
* | *Copper sulfate neutralized with hydrated lime (Bordeaux mixture; "vineyard sprayer's lung") | ||
*Diatomaceous earth (Fuller's earth, aluminum silicate with Fe and Mg) | *Diatomaceous earth (Fuller's earth, aluminum silicate with Fe and Mg) | ||
*Diphenylmethane diisocyanate | *[[Diphenylmethane diisocyanate]] | ||
*Farmer's lung (Macropolyspora faeni) | *Farmer's lung (Macropolyspora faeni) | ||
*Fats | *Fats | ||
*Grain handler's lung (Thermactinomyces vulgaris) | *Grain handler's lung (Thermactinomyces vulgaris) | ||
*Graphite ("carbon pneumoconiosis") | *[[Graphite]] ("carbon pneumoconiosis") | ||
*Hard metal dusts (cadmium, tungsten, titanium and cobalt) | *Hard metal dusts ([[cadmium]], [[tungsten]], [[titanium]] and [[cobalt]]) | ||
*Hematite(mixed dusts of iron oxide, silica and silicates; "siderosilicosis") | *Hematite(mixed dusts of iron oxide, silica and silicates; "siderosilicosis") | ||
*Humidifier or air conditioner lung (T. sacchari) | *Humidifier or air conditioner lung (T. sacchari) | ||
*Hydrocarbons | *[[Hydrocarbons]] | ||
*Iron ("siderosis") | *[[Iron]] ("siderosis") | ||
*Kaolin or "china clay" (hydrated aluminum silicate) | *[[Kaolin]] or "china clay" (hydrated aluminum silicate) | ||
*Mercury | *[[Mercury]] | ||
*Methyl isocyanate | *Methyl isocyanate | ||
*Mica (principally K and Mg aluminum silicates) | *Mica (principally K and Mg aluminum silicates) | ||
| Line 319: | Line 318: | ||
*Nepheline (hard rock containing mixed silicates) | *Nepheline (hard rock containing mixed silicates) | ||
*Oils | *Oils | ||
*Oxides of nitrogen | *Oxides of [[nitrogen]] | ||
*Oxides of zinc, copper, manganese, cadmium, iron, magnesium, nickel, brass, selenium, tin, and antimony | *Oxides of [[zinc]], [[copper]], [[manganese]], [[cadmium]], [[iron]], [[magnesium]], [[nickel]], [[brass]], [[selenium]], [[tin]], and [[antimony]] | ||
*Oxygen | *[[Oxygen]] | ||
*Penicillium species | *Penicillium species | ||
*Popcorn worker's lung (butter flavoring) | *Popcorn worker's lung (butter flavoring) | ||
| Line 327: | Line 326: | ||
*Pyrethrum (a natural insecticide) | *Pyrethrum (a natural insecticide) | ||
*Rare earths (cerium, scandium, yttrium, lanthanum) | *Rare earths (cerium, scandium, yttrium, lanthanum) | ||
*Silica ("silicosis") | *[[Silica]] ("silicosis") | ||
*Sulfur dioxide | *Sulfur dioxide | ||
*Synthetic - fiber lung (Orlon, polyesters, nylon, acrylic) | *Synthetic - fiber lung (Orlon, polyesters, nylon, acrylic) | ||
*Talc (hydrated Mg silicates; "talcosis") | *[[Talc]] (hydrated Mg silicates; "talcosis") | ||
*Thermosetting resins (rubber tire workers) | *Thermosetting resins (rubber tire workers) | ||
*Tin ("stannosis") | *[[Tin]] ("stannosis") | ||
*Toluene diisocyanate (TDI - asthmatic reactions prominent) | *[[Toluene diisocyanate]] (TDI - asthmatic reactions prominent) | ||
*Trimellitic anhydride toxicity | *Trimellitic anhydride toxicity | ||
*Vinyl chloride, polyvinyl chloride powder | *[[Vinyl chloride]], polyvinyl chloride powder | ||
}} | }} | ||
Revision as of 19:39, 15 February 2018
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Occupational lung disease Microchapters |
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Differentiating Occupational lung disease from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Occupational lung disease causes On the Web |
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American Roentgen Ray Society Images of Occupational lung disease causes |
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Directions to Hospitals Treating Coalworker's pneumoconiosis |
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Risk calculators and risk factors for Occupational lung disease causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Occupational lung disease may be caused by organic dust such as thermophilic and true fungi, and bacteria and animal proteins, or by inorganic dust such as, silicates, carbons and metals, or by agents other than organic or inorganic dusts such as, chemicals, gases, fumes, vapors and aerosols.
Causes
Life-threatening Causes
- Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.[1][2]
- Life-threatening causes of occupational lung disease include chemical gas inhalation such as chlorine or sarin gas.
Common Causes
Occupational lung disease may be caused by:[3][4]
- Silica ("silicosis")
- Asbestos ("asbestosis")
- Beryllium ("berylliosis")
- Mica (principally K and Mg aluminum silicates)
- Portland cement
- Aluminum silicates (sericite, sillimanite, zeolite)
- Aluminum
- Hard metal dusts (cadmium, tungsten, titanium and cobalt)
- Iron ("siderosis")
- Coal dust ("coal worker's pneumoconiosis")
- Graphite ("carbon pneumoconiosis")
- Farmer's lung (Macropolyspora faeni)
- Grain handler's lung (Thermactinomyces vulgaris)
- Humidifier or air conditioner lung (T. sacchari)
- Aspergillus
- Copper sulfate neutralized with hydrated lime (Bordeaux mixture; "vineyard sprayer's lung")
- Bird fancier's disease
Less Common Causes
Less common causes of occupational lung disease include:[5][6]
- Vinyl chloride, polyvinyl chloride powder
- Oxygen
- Oxides of nitrogen
- Sulfur dioxide
- Chlorine gas
- Methyl isocyanate
- Oxides of zinc, copper, manganese, cadmium, iron, magnesium, nickel, brass, selenium, tin, and antimony
- Diphenylmethane diisocyanate
- Trimellitic anhydride toxicity
- Hydrocarbons
- Thermosetting resins (rubber tire workers)
- Toluene diisocyanate (TDI - asthmatic reactions prominent)
- Talc (hydrated Mg silicates; "talcosis")
- Kaolin or "china clay" (hydrated aluminum silicate)
- Popcorn worker's lung (butter flavoring)
- Oxygen
- Mercury
- Oils
- Fats
- Pyrethrum (a natural insecticide)
- Nepheline (hard rock containing mixed silicates)
- Diatomaceous earth (Fuller's earth, aluminum silicate with Fe and Mg)
- Tin ("stannosis")
- Antimony
- Hematite (mixed dusts of iron oxide, silica and silicates; "siderosilicosis")
- Mixed dusts of silver and iron oxide ("argyrosiderosis")
- Copper sulfate neutralized with hydrated lime (Bordeaux mixture; "vineyard sprayer's lung")
- Rare earths (cerium, scandium, yttrium, lanthanum)
- Cryptostroma corticale
- Aureobasidium pullulans
- Penicillium species
- Bacillus subtilis
- B. cereus
- Synthetic - fiber lung (Orlon, polyesters, nylon, acrylic)
- Bakelite worker's lung
Genetic Causes
- Occupational lung disease may be triggered by a mutation in the following genes:[7]
- MUC5B promoter polymorphism
- Has been identified as causing progression in interstitial lung fibrosis
- HLA-DPB1*0201 polymorphisms
- NAT2 acetylation
- Associated with bladder cancer with exposure to benzine dyes
- HLA class II genes such as HLA-DQB1*0503
- Associated with toluene diisocyanate-induced occupational asthma
- Polymorphisms in exons 3 of Tyr113His (C113T) and 4 His139Arg (G139A) of the mEH gene
- Associated with organic dust-induced chronic airways disease where the activity of microsomal epoxide hydrolase slows down
- MUC5B promoter polymorphism
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | Chemical sources:
•Synthetic - fiber lung (Orlon, polyesters, nylon, acrylic) •Bakelite worker's lung •Vinyl chloride, polyvinyl chloride powder Gases: •Oxygen •Oxides of nitrogen •Chlorine gas •Methyl isocyanate Fumes: •Oxides of zinc, coppe, manganese, cadmium, iron, magnesium, nickel, brass, selenium, tin, and antimony •Trimellitic anhydride toxicity Vapors: •Thermosetting resins (rubber tire workers) •Toluene diisocyanate (TDI - asthmatic reactions prominent) Aerosols: •Oils •Fats •Pyrethrum (a natural insecticide) |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | •Farmer's lung (Macropolyspora faeni)
•Grain handler's lung (Thermactinomyces vulgaris) •Humidifier or air conditioner lung (T. sacchari) •Cryptostroma corticale •Penicillium species •Bacillus subtilis •B. cereus •Bird fancier's disease •Nepheline (hard rock containing mixed silicates) •Diatomaceous earth (Fuller's earth, aluminum silicate with Fe and Mg) |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | •Coal dust ("coal worker's pneumoconiosis")
•[[[Graphite]] ("carbon pneumoconiosis") •Tin ("stannosis") •Hard metal dusts (cadmium, tungsten, titanium and cobalt) •Iron ("siderosis") •Hematite (mixed dusts of iron oxide, silica and silicates; "siderosilicosis") •Mixed dusts of silver and iron oxide ("argyrosiderosis") •Copper sulfate neutralized with hydrated lime (Bordeaux mixture; "vineyard sprayer's lung") •Rare earths (cerium, scandium, yttrium, lanthanum) |
Causes in Alphabetical Order
The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3References
- ↑ Goldman RH, Peters JM (1981). "The occupational and environmental health history". JAMA. 246 (24): 2831–6. PMID 7310975.
- ↑ Banauch GI, Hall C, Weiden M, Cohen HW, Aldrich TK, Christodoulou V, Arcentales N, Kelly KJ, Prezant DJ (2006). "Pulmonary function after exposure to the World Trade Center collapse in the New York City Fire Department". Am. J. Respir. Crit. Care Med. 174 (3): 312–9. doi:10.1164/rccm.200511-1736OC. PMC 2648115. PMID 16645172.
- ↑ Banauch GI, Dhala A, Alleyne D, Alva R, Santhyadka G, Krasko A, Weiden M, Kelly KJ, Prezant DJ (2005). "Bronchial hyperreactivity and other inhalation lung injuries in rescue/recovery workers after the World Trade Center collapse". Crit. Care Med. 33 (1 Suppl): S102–6. PMID 15640671.
- ↑ Prezant DJ, Weiden M, Banauch GI, McGuinness G, Rom WN, Aldrich TK, Kelly KJ (2002). "Cough and bronchial responsiveness in firefighters at the World Trade Center site". N. Engl. J. Med. 347 (11): 806–15. doi:10.1056/NEJMoa021300. PMID 12226151.
- ↑ Tarlo SM, Lemiere C (2014). "Occupational asthma". N. Engl. J. Med. 370 (7): 640–9. doi:10.1056/NEJMra1301758. PMID 24521110.
- ↑ Tarlo SM, Balmes J, Balkissoon R, Beach J, Beckett W, Bernstein D, Blanc PD, Brooks SM, Cowl CT, Daroowalla F, Harber P, Lemiere C, Liss GM, Pacheco KA, Redlich CA, Rowe B, Heitzer J (2008). "Diagnosis and management of work-related asthma: American College Of Chest Physicians Consensus Statement". Chest. 134 (3 Suppl): 1S–41S. doi:10.1378/chest.08-0201. PMID 18779187.
- ↑ Christiani DC, Mehta AJ, Yu CL (2008). "Genetic susceptibility to occupational exposures". Occup Environ Med. 65 (6): 430–6, quiz 436, 397. doi:10.1136/oem.2007.033977. PMC 3815576. PMID 18487431.