Polycythemia vera other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Other diagnostic studies for polycythemia vera include [[bone marrow aspiration]] and [[biopsy|trephine biopsy]]. Erythropoietin levels can also be measured. | Other diagnostic studies for polycythemia vera include [[bone marrow aspiration]] and [[biopsy|trephine biopsy]]. [[Erythropoietin]] levels can also be measured. | ||
==Other diagnostic studies== | ==Other diagnostic studies== | ||
Other diagnostic studies for polycythemia vera include: | Other diagnostic studies for polycythemia vera include: | ||
*'''[[Bone marrow aspiration]]''': This is an invasive diagnostic procedure that is sometimes required for the diagnosis of polycythemia vera. Bone marrow biopsy usually shows high proportions of [[leukocytes]], [[erythrocytes]], and [[thrombocytes]]. This is referred to as [[panmyelosis]]. These findings on a bone marrow biopsy constitute one of the major diagnostic criteria for polycythemia vera in the 2016 WHO classification of myeloproliferative neoplasms.<ref name="pmid27069254">{{cite journal| author=Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM et al.| title=The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. | journal=Blood | year= 2016 | volume= 127 | issue= 20 | pages= 2391-405 | pmid=27069254 | doi=10.1182/blood-2016-03-643544 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27069254 }} </ref> | *'''[[Bone marrow aspiration]]''': This is an invasive diagnostic procedure that is sometimes required for the diagnosis of polycythemia vera. [[Bone marrow biopsy]] usually shows high proportions of [[leukocytes]], [[erythrocytes]], and [[thrombocytes]]. This is referred to as [[panmyelosis]]. These findings on a bone marrow biopsy constitute one of the major diagnostic criteria for polycythemia vera in the 2016 WHO classification of myeloproliferative neoplasms.<ref name="pmid27069254">{{cite journal| author=Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM et al.| title=The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. | journal=Blood | year= 2016 | volume= 127 | issue= 20 | pages= 2391-405 | pmid=27069254 | doi=10.1182/blood-2016-03-643544 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27069254 }} </ref> | ||
*'''[[Erythropoietin]] level''': [[Erythropoietin]] level is usually low in polycythemia vera. This is because polycythemia vera is characterized by autonomous production of [[red blood cells]] in an erythropoietin-independent manner. | *'''[[Erythropoietin]] level''': [[Erythropoietin]] level is usually low in polycythemia vera. This is because polycythemia vera is characterized by autonomous production of [[red blood cells]] in an [[erythropoietin]]-independent manner. | ||
==Gallery== | ==Gallery== | ||
<gallery widths=200px class="center"> | <gallery widths="200px" class="center"> | ||
CDR554337-274.jpg| Bone marrow aspiration and biopsy. After a small area of skin is numbed, a Jamshidi needle (a long, hollow needle) is inserted into the patient’s hip bone. Samples of blood, bone, and bone marrow are removed for examination under a microscope.<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/leukemia/patient/cml-treatment-pdq</ref> | CDR554337-274.jpg| Bone marrow aspiration and biopsy. After a small area of skin is numbed, a Jamshidi needle (a long, hollow needle) is inserted into the patient’s hip bone. Samples of blood, bone, and bone marrow are removed for examination under a microscope.<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/leukemia/patient/cml-treatment-pdq</ref> | ||
</gallery> | </gallery> | ||
Revision as of 15:48, 11 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
Other diagnostic studies for polycythemia vera include bone marrow aspiration and trephine biopsy. Erythropoietin levels can also be measured.
Other diagnostic studies
Other diagnostic studies for polycythemia vera include:
- Bone marrow aspiration: This is an invasive diagnostic procedure that is sometimes required for the diagnosis of polycythemia vera. Bone marrow biopsy usually shows high proportions of leukocytes, erythrocytes, and thrombocytes. This is referred to as panmyelosis. These findings on a bone marrow biopsy constitute one of the major diagnostic criteria for polycythemia vera in the 2016 WHO classification of myeloproliferative neoplasms.[1]
- Erythropoietin level: Erythropoietin level is usually low in polycythemia vera. This is because polycythemia vera is characterized by autonomous production of red blood cells in an erythropoietin-independent manner.
Gallery
-
![Bone marrow aspiration and biopsy. After a small area of skin is numbed, a Jamshidi needle (a long, hollow needle) is inserted into the patient’s hip bone. Samples of blood, bone, and bone marrow are removed for examination under a microscope.[2]](/images/e/e4/CDR554337-274.jpg)
Bone marrow aspiration and biopsy. After a small area of skin is numbed, a Jamshidi needle (a long, hollow needle) is inserted into the patient’s hip bone. Samples of blood, bone, and bone marrow are removed for examination under a microscope.[2]
![Bone marrow aspiration and biopsy. After a small area of skin is numbed, a Jamshidi needle (a long, hollow needle) is inserted into the patient’s hip bone. Samples of blood, bone, and bone marrow are removed for examination under a microscope.[2]](/index.php/File:CDR554337-274.jpg)
References
- ↑ Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM; et al. (2016). "The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia". Blood. 127 (20): 2391–405. doi:10.1182/blood-2016-03-643544. PMID 27069254.
- ↑ National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/leukemia/patient/cml-treatment-pdq