Cystic fibrosis CT: Difference between revisions
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==CT scan== | ==CT scan== | ||
Computed tomography (CT scan) findings in patients with cystic fibrosis are more sensitive as compared to the pulmonary function tests. It has a crucial role in the assessment of pulmonary damage over time, detecting complications and monitoring treatment.<ref name="pmid271039452">{{cite journal |vauthors=Rybacka A, Karmelita-Katulska K |title=The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis |journal=Pol J Radiol |volume=81 |issue= |pages=141–5 |date=2016 |pmid=27103945 |pmc=4821342 |doi=10.12659/PJR.896051 |url=}}</ref> | [[Computed tomography|Computed tomography (CT scan)]] findings in patients with cystic fibrosis are more [[Sensitivity (tests)|sensitive]] as compared to the [[Spirometry|pulmonary function tests]]. It has a crucial role in the assessment of pulmonary damage over time, detecting [[Complication (medicine)|complications]] and monitoring treatment.<ref name="pmid271039452">{{cite journal |vauthors=Rybacka A, Karmelita-Katulska K |title=The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis |journal=Pol J Radiol |volume=81 |issue= |pages=141–5 |date=2016 |pmid=27103945 |pmc=4821342 |doi=10.12659/PJR.896051 |url=}}</ref> | ||
===Chest=== | ===Chest=== | ||
* Mosaic attenuation (localized hyperinflation due to small airway obstruction) on | * Mosaic attenuation (localized hyperinflation due to small [[airway obstruction]]) on expiratory chest [[Computed tomography|computed tomography (CT)]] is common in early life cystic fibrosis and often referred to as "[[air trapping]]".<ref name="pmid28682006">{{cite journal |vauthors=Rosenow T, Ramsey K, Turkovic L, Murray CP, Mok LC, Hall GL, Stick SM |title=Air trapping in early cystic fibrosis lung disease-Does CT tell the full story? |journal=Pediatr. Pulmonol. |volume=52 |issue=9 |pages=1150–1156 |date=September 2017 |pmid=28682006 |doi=10.1002/ppul.23754 |url=}}</ref> | ||
==== Most common CT scan findings ==== | ==== Most common CT scan findings ==== | ||
Most common CT scan findings include:<ref name="pmid271039452">{{cite journal |vauthors=Rybacka A, Karmelita-Katulska K |title=The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis |journal=Pol J Radiol |volume=81 |issue= |pages=141–5 |date=2016 |pmid=27103945 |pmc=4821342 |doi=10.12659/PJR.896051 |url=}}</ref><ref name="pmid17287306">{{cite journal |vauthors=Aziz ZA, Davies JC, Alton EW, Wells AU, Geddes DM, Hansell DM |title=Computed tomography and cystic fibrosis: promises and problems |journal=Thorax |volume=62 |issue=2 |pages=181–6 |date=February 2007 |pmid=17287306 |pmc=2111250 |doi=10.1136/thx.2005.054379 |url=}}</ref> | Most common CT scan findings include:<ref name="pmid271039452">{{cite journal |vauthors=Rybacka A, Karmelita-Katulska K |title=The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis |journal=Pol J Radiol |volume=81 |issue= |pages=141–5 |date=2016 |pmid=27103945 |pmc=4821342 |doi=10.12659/PJR.896051 |url=}}</ref><ref name="pmid17287306">{{cite journal |vauthors=Aziz ZA, Davies JC, Alton EW, Wells AU, Geddes DM, Hansell DM |title=Computed tomography and cystic fibrosis: promises and problems |journal=Thorax |volume=62 |issue=2 |pages=181–6 |date=February 2007 |pmid=17287306 |pmc=2111250 |doi=10.1136/thx.2005.054379 |url=}}</ref> | ||
* Peribronchial thickening (85%) | * Peribronchial thickening (85%) | ||
* Mucous plugging (79%) | * [[Mucus|Mucous]] plugging (79%) | ||
* Bronchiectasis which is progressive, irreversible (76%) | * [[Bronchiectasis]] which is progressive, [[Irreversibility|irreversible]] (76%) | ||
==== Less common CT scan findings ==== | ==== Less common CT scan findings ==== | ||
Less common CT scan findings include:<ref name="pmid271039452">{{cite journal |vauthors=Rybacka A, Karmelita-Katulska K |title=The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis |journal=Pol J Radiol |volume=81 |issue= |pages=141–5 |date=2016 |pmid=27103945 |pmc=4821342 |doi=10.12659/PJR.896051 |url=}}</ref><ref name="pmid17287306" /> | Less common CT scan findings include:<ref name="pmid271039452">{{cite journal |vauthors=Rybacka A, Karmelita-Katulska K |title=The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis |journal=Pol J Radiol |volume=81 |issue= |pages=141–5 |date=2016 |pmid=27103945 |pmc=4821342 |doi=10.12659/PJR.896051 |url=}}</ref><ref name="pmid17287306" /> | ||
* Abscesses | * [[Abscess|Abscesses]] | ||
* Emphysematous bullae | * Emphysematous bullae | ||
* Hyperinflation | * Hyperinflation | ||
* Collapse | * Collapse | ||
* Consolidation | * [[Consolidation (medicine)|Consolidation]] | ||
* Ground-glass opacities | * Ground-glass opacities | ||
* Acinar nodules | * [[Acinus|Acinar]] nodules | ||
* Thickening of interlobular and intralobular septa | * Thickening of interlobular and intralobular septa | ||
===Abdomen=== | ===Abdomen=== | ||
CT scan of abdomen in patients with cystic fibrosis may include these findings:<ref name="pmid14753605">{{cite journal |vauthors=Carucci LR, Jacobs JE |title=Focal fatty sparing of the pancreatic head in cystic fibrosis: CT findings |journal=Abdom Imaging |volume=28 |issue=6 |pages=853–5 |date=2003 |pmid=14753605 |doi= |url=}}</ref><ref name="pmid9755398">{{cite journal |vauthors=Lugo-Olivieri CH, Soyer PA, Fishman EK |title=Cystic fibrosis: spectrum of thoracic and abdominal CT findings in the adult patient |journal=Clin Imaging |volume=22 |issue=5 |pages=346–54 |date=1998 |pmid=9755398 |doi= |url=}}</ref> | [[Computed tomography|CT scan]] of abdomen in patients with cystic fibrosis may include these findings:<ref name="pmid14753605">{{cite journal |vauthors=Carucci LR, Jacobs JE |title=Focal fatty sparing of the pancreatic head in cystic fibrosis: CT findings |journal=Abdom Imaging |volume=28 |issue=6 |pages=853–5 |date=2003 |pmid=14753605 |doi= |url=}}</ref><ref name="pmid9755398">{{cite journal |vauthors=Lugo-Olivieri CH, Soyer PA, Fishman EK |title=Cystic fibrosis: spectrum of thoracic and abdominal CT findings in the adult patient |journal=Clin Imaging |volume=22 |issue=5 |pages=346–54 |date=1998 |pmid=9755398 |doi= |url=}}</ref> | ||
* Diffuse and complete fatty replacement of pancreas is the most common imaging appearance. | * Diffuse and complete fatty replacement of [[pancreas]] is the most common imaging appearance. | ||
* Fibrosis of the pancreas can be detectable on CT scan. | * [[Fibrosis]] of the [[pancreas]] can be detectable on [[Computed tomography|CT scan]]. | ||
* Intestinal findings on CT may include obstruction (more common in children). | * [[Intestine|Intestinal]] findings on [[Computed tomography|CT]] may include [[obstruction]] (more common in children). | ||
===Images=== | ===Images=== | ||
CT demonstrates mucous plugging and complete pancreatic atrophy<ref name="urlCystic fibrosis | Radiology Case | Radiopaedia.org">{{cite web |url=https://radiopaedia.org/cases/cystic-fibrosis-5 |title=Cystic fibrosis | Radiology Case | Radiopaedia.org |format= |work= |accessdate=}}</ref> | [[Computed tomography|CT]] demonstrates [[Mucus|mucous]] plugging and complete [[Pancreas|pancreatic]] [[atrophy]]<ref name="urlCystic fibrosis | Radiology Case | Radiopaedia.org">{{cite web |url=https://radiopaedia.org/cases/cystic-fibrosis-5 |title=Cystic fibrosis | Radiology Case | Radiopaedia.org |format= |work= |accessdate=}}</ref> | ||
<gallery> | <gallery> | ||
Revision as of 17:32, 5 March 2018
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Cystic fibrosis Microchapters |
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Cystic fibrosis CT On the Web |
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American Roentgen Ray Society Images of Cystic fibrosis CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
CT scan
Computed tomography (CT scan) findings in patients with cystic fibrosis are more sensitive as compared to the pulmonary function tests. It has a crucial role in the assessment of pulmonary damage over time, detecting complications and monitoring treatment.[1]
Chest
- Mosaic attenuation (localized hyperinflation due to small airway obstruction) on expiratory chest computed tomography (CT) is common in early life cystic fibrosis and often referred to as "air trapping".[2]
Most common CT scan findings
Most common CT scan findings include:[1][3]
- Peribronchial thickening (85%)
- Mucous plugging (79%)
- Bronchiectasis which is progressive, irreversible (76%)
Less common CT scan findings
Less common CT scan findings include:[1][3]
- Abscesses
- Emphysematous bullae
- Hyperinflation
- Collapse
- Consolidation
- Ground-glass opacities
- Acinar nodules
- Thickening of interlobular and intralobular septa
Abdomen
CT scan of abdomen in patients with cystic fibrosis may include these findings:[4][5]
- Diffuse and complete fatty replacement of pancreas is the most common imaging appearance.
- Fibrosis of the pancreas can be detectable on CT scan.
- Intestinal findings on CT may include obstruction (more common in children).
Images
CT demonstrates mucous plugging and complete pancreatic atrophy[6]
References
- ↑ 1.0 1.1 1.2 Rybacka A, Karmelita-Katulska K (2016). "The Role of Computed Tomography in Monitoring Patients with Cystic Fibrosis". Pol J Radiol. 81: 141–5. doi:10.12659/PJR.896051. PMC 4821342. PMID 27103945.
- ↑ Rosenow T, Ramsey K, Turkovic L, Murray CP, Mok LC, Hall GL, Stick SM (September 2017). "Air trapping in early cystic fibrosis lung disease-Does CT tell the full story?". Pediatr. Pulmonol. 52 (9): 1150–1156. doi:10.1002/ppul.23754. PMID 28682006.
- ↑ 3.0 3.1 Aziz ZA, Davies JC, Alton EW, Wells AU, Geddes DM, Hansell DM (February 2007). "Computed tomography and cystic fibrosis: promises and problems". Thorax. 62 (2): 181–6. doi:10.1136/thx.2005.054379. PMC 2111250. PMID 17287306.
- ↑ Carucci LR, Jacobs JE (2003). "Focal fatty sparing of the pancreatic head in cystic fibrosis: CT findings". Abdom Imaging. 28 (6): 853–5. PMID 14753605.
- ↑ Lugo-Olivieri CH, Soyer PA, Fishman EK (1998). "Cystic fibrosis: spectrum of thoracic and abdominal CT findings in the adult patient". Clin Imaging. 22 (5): 346–54. PMID 9755398.
- ↑ "Cystic fibrosis | Radiology Case | Radiopaedia.org".