Neurosyphilis X-ray: Difference between revisions

Jump to navigation Jump to search
(Created page with "__NOTOC__ {{CMG}}; {{AE}}{{MMJ}} {{Neurosyphilis}} ==Overview== Chest x-ray is not routinely used to detect syphilis. However, complications associated with syphilis may be de...")
 
No edit summary
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{CMG}}; {{AE}}{{MMJ}}
{{CMG}}; {{AE}}{{MMJ}}
{{Neurosyphilis}}
{{Neurosyphilis}}
==Overview==
==Overview==
Chest x-ray is not routinely used to detect syphilis. However, complications associated with syphilis may be detected incidentally on x-ray. Cardiovascular manifestations of syphilis may be seen as a non-specific widening of the aortic or mediastinal silhouettes on PA and lateral chest x-ray.<ref name="radiop"> https://radiopaedia.org/articles/thoracic-aortic-aneurysm. Accessed on September 28th, 2016. </ref><ref name="radiop1"> https://radiopaedia.org/articles/ascending-aortic-aneurysm. Accessed on September 28th, 2016. </ref> Linear calcification of the ascending aorta is an almost pathognomonic finding of syphlitic [[aortitis]].<ref name="pmid21427433">{{cite journal| author=Dabis R, Radcliffe K| title=Is it useful to perform a chest X-ray in asymptomatic patients with late latent syphilis? | journal=Int J STD AIDS | year= 2011 | volume= 22 | issue= 2 | pages= 105-6 | pmid=21427433 | doi=10.1258/ijsa.2010.010248 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21427433  }} </ref> This may prompt the clinician to order further imaging studies for confirmation. Additionally, on [[Chest X-ray|chest x-ray]], secondary pulmonary syphilis may be characterized by the bilateral infiltrates, [[pleural effusion]], subpleural nodules, and [[lymphadenopathy]].<ref name="pmid4175712">{{cite journal| author=Biro L, Hill AC, Kuflik EG| title=Secondary syphilis with unusual clinical and laboratory findings. | journal=JAMA | year= 1968 | volume= 206 | issue= 4 | pages= 889-91 | pmid=4175712 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4175712  }} </ref><ref name="pmid16392072">{{cite journal| author=David G, Perpoint T, Boibieux A, Pialat JB, Salord H, Devouassoux M et al.| title=Secondary pulmonary syphilis: report of a likely case and literature review. | journal=Clin Infect Dis | year= 2006 | volume= 42 | issue= 3 | pages= e11-5 | pmid=16392072 | doi=10.1086/499104 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16392072  }} </ref><ref name="pmid: PMC3056368">{{cite journal| author=Burger HG, Baker HW, Buckler HM, Healy DL, Kovacs GT| title=Advances in reproductive medicine: Australian contributions. | journal=Aust N Z J Med | year= 1988 | volume= 18 | issue= 3 | pages= 263-77 | pmid=: PMC3056368 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3056368  }} </ref><ref name="pmid6613117">{{cite journal| author=Coleman DL, McPhee SJ, Ross TF, Naughton JL| title=Secondary syphilis with pulmonary involvement. | journal=West J Med | year= 1983 | volume= 138 | issue= 6 | pages= 875-8 | pmid=6613117 | doi= | pmc=1010855 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6613117  }} </ref><ref name="pmid4074225">{{cite journal| author=Geer LL, Warshauer DM, Delany DJ| title=Pulmonary nodule in secondary syphilis. | journal=Australas Radiol | year= 1985 | volume= 29 | issue= 3 | pages= 240-2 | pmid=4074225 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4074225  }} </ref> X ray findings may also include osteolytic bone lesions.<ref name="pmid921426">{{cite journal| author=Shore RN, Kiesel HA, Bennett HD| title=Osteolytic lesions in secondary syphilis. | journal=Arch Intern Med | year= 1977 | volume= 137 | issue= 10 | pages= 1465-7 | pmid=921426 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=921426  }} </ref>
 
Chest x-ray is not routinely used to detect neurosyphilis. However, complications associated with syphilis may be detected incidentally on x-ray. Cardiovascular manifestations of syphilis may be seen as a non-specific widening of the aortic or mediastinal silhouettes on PA and lateral chest x-ray.<ref name="radiop">https://radiopaedia.org/articles/thoracic-aortic-aneurysm. Accessed on September 28th, 2016. </ref><ref name="radiop1">https://radiopaedia.org/articles/ascending-aortic-aneurysm. Accessed on September 28th, 2016. </ref> Linear calcification of the ascending aorta is an almost pathognomonic finding of syphlitic [[aortitis]].<ref name="pmid21427433">{{cite journal| author=Dabis R, Radcliffe K| title=Is it useful to perform a chest X-ray in asymptomatic patients with late latent syphilis? | journal=Int J STD AIDS | year= 2011 | volume= 22 | issue= 2 | pages= 105-6 | pmid=21427433 | doi=10.1258/ijsa.2010.010248 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21427433  }} </ref> This may prompt the clinician to order further imaging studies for confirmation. Additionally, on [[Chest X-ray|chest x-ray]], secondary pulmonary syphilis may be characterized by the bilateral infiltrates, [[pleural effusion]], subpleural nodules, and [[lymphadenopathy]].<ref name="pmid4175712">{{cite journal| author=Biro L, Hill AC, Kuflik EG| title=Secondary syphilis with unusual clinical and laboratory findings. | journal=JAMA | year= 1968 | volume= 206 | issue= 4 | pages= 889-91 | pmid=4175712 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4175712  }} </ref><ref name="pmid16392072">{{cite journal| author=David G, Perpoint T, Boibieux A, Pialat JB, Salord H, Devouassoux M et al.| title=Secondary pulmonary syphilis: report of a likely case and literature review. | journal=Clin Infect Dis | year= 2006 | volume= 42 | issue= 3 | pages= e11-5 | pmid=16392072 | doi=10.1086/499104 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16392072  }} </ref><ref name="pmid: PMC3056368">{{cite journal| author=Burger HG, Baker HW, Buckler HM, Healy DL, Kovacs GT| title=Advances in reproductive medicine: Australian contributions. | journal=Aust N Z J Med | year= 1988 | volume= 18 | issue= 3 | pages= 263-77 | pmid=: PMC3056368 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3056368  }} </ref><ref name="pmid6613117">{{cite journal| author=Coleman DL, McPhee SJ, Ross TF, Naughton JL| title=Secondary syphilis with pulmonary involvement. | journal=West J Med | year= 1983 | volume= 138 | issue= 6 | pages= 875-8 | pmid=6613117 | doi= | pmc=1010855 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6613117  }} </ref><ref name="pmid4074225">{{cite journal| author=Geer LL, Warshauer DM, Delany DJ| title=Pulmonary nodule in secondary syphilis. | journal=Australas Radiol | year= 1985 | volume= 29 | issue= 3 | pages= 240-2 | pmid=4074225 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4074225  }} </ref> X ray findings may also include osteolytic bone lesions.<ref name="pmid921426">{{cite journal| author=Shore RN, Kiesel HA, Bennett HD| title=Osteolytic lesions in secondary syphilis. | journal=Arch Intern Med | year= 1977 | volume= 137 | issue= 10 | pages= 1465-7 | pmid=921426 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=921426  }} </ref>


==X-ray==
==X-ray==
X-ray is not directly used to detect the neurosyphilis but it may helps to diagnose other manifestations of syphilis disease.
X-ray findings in syphilis are largely non-specific and may be found incidentally. Common incidental x-ray findings of syphilis may include:
X-ray findings in syphilis are largely non-specific and may be found incidentally. Common incidental x-ray findings of syphilis may include:
===Pulmonary===
===Pulmonary===
Line 15: Line 19:


===Cardiac===
===Cardiac===
Chest x-ray is not routinely used to detect thoracic manifestations of syphilis. However, thoracic aortic [[aneurysms]] associated with syphilis may be detected incidentally as a widening of the aortic or [[Mediastinum|mediastinal]] silhouettes on PA and lateral chest x-ray. Accurate assessment of the exact size is difficult and further imaging studies are required to do so.<ref name="radiop"> https://radiopaedia.org/articles/thoracic-aortic-aneurysm. Accessed on September 28th, 2016. </ref><ref name="radiop1"> https://radiopaedia.org/articles/ascending-aortic-aneurysm. Accessed on September 28th, 2016. </ref> Linear calcification of the ascending [[aorta]] is an almost pathognomonic finding of syphlitic aortitis.<ref name="pmid21427433">{{cite journal| author=Dabis R, Radcliffe K| title=Is it useful to perform a chest X-ray in asymptomatic patients with late latent syphilis? | journal=Int J STD AIDS | year= 2011 | volume= 22 | issue= 2 | pages= 105-6 | pmid=21427433 | doi=10.1258/ijsa.2010.010248 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21427433  }} </ref>
Chest x-ray is not routinely used to detect thoracic manifestations of syphilis. However, thoracic aortic [[aneurysms]] associated with syphilis may be detected incidentally as a widening of the aortic or [[Mediastinum|mediastinal]] silhouettes on PA and lateral chest x-ray. Accurate assessment of the exact size is difficult and further imaging studies are required to do so.<ref name="radiop">https://radiopaedia.org/articles/thoracic-aortic-aneurysm. Accessed on September 28th, 2016. </ref><ref name="radiop1">https://radiopaedia.org/articles/ascending-aortic-aneurysm. Accessed on September 28th, 2016. </ref> Linear calcification of the ascending [[aorta]] is an almost pathognomonic finding of syphlitic aortitis.<ref name="pmid21427433">{{cite journal| author=Dabis R, Radcliffe K| title=Is it useful to perform a chest X-ray in asymptomatic patients with late latent syphilis? | journal=Int J STD AIDS | year= 2011 | volume= 22 | issue= 2 | pages= 105-6 | pmid=21427433 | doi=10.1258/ijsa.2010.010248 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21427433  }} </ref>
===Bone===
===Bone===
X-ray findings may also include osteolytic bone lesions.<ref name="pmid921426">{{cite journal| author=Shore RN, Kiesel HA, Bennett HD| title=Osteolytic lesions in secondary syphilis. | journal=Arch Intern Med | year= 1977 | volume= 137 | issue= 10 | pages= 1465-7 | pmid=921426 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=921426  }} </ref>
X-ray findings may also include osteolytic bone lesions.<ref name="pmid921426">{{cite journal| author=Shore RN, Kiesel HA, Bennett HD| title=Osteolytic lesions in secondary syphilis. | journal=Arch Intern Med | year= 1977 | volume= 137 | issue= 10 | pages= 1465-7 | pmid=921426 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=921426  }} </ref>
Line 23: Line 27:
{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}


[[Category:Gynecology]]
[[Category:Gynecology]]


[[Category:Primary care]]
[[Category:Primary care]]

Revision as of 15:53, 19 March 2018


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Neurosyphilis Microchapters

Home

Patient Information

Overview

Historical perspective

Classification

Pathophysiology

Causes

Differentiating Neurosyphilis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Neurosyphilis X-ray On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Neurosyphilis X-ray

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Neurosyphilis X-ray

CDC on Neurosyphilis X-ray

Neurosyphilis X-ray in the news

Blogs on Neurosyphilis X-ray

Directions to Hospitals Treating Neurosyphilis

Risk calculators and risk factors for Neurosyphilis X-ray

Overview

Chest x-ray is not routinely used to detect neurosyphilis. However, complications associated with syphilis may be detected incidentally on x-ray. Cardiovascular manifestations of syphilis may be seen as a non-specific widening of the aortic or mediastinal silhouettes on PA and lateral chest x-ray.[1][2] Linear calcification of the ascending aorta is an almost pathognomonic finding of syphlitic aortitis.[3] This may prompt the clinician to order further imaging studies for confirmation. Additionally, on chest x-ray, secondary pulmonary syphilis may be characterized by the bilateral infiltrates, pleural effusion, subpleural nodules, and lymphadenopathy.[4][5][6][7][8] X ray findings may also include osteolytic bone lesions.[9]

X-ray

X-ray is not directly used to detect the neurosyphilis but it may helps to diagnose other manifestations of syphilis disease.

X-ray findings in syphilis are largely non-specific and may be found incidentally. Common incidental x-ray findings of syphilis may include:

Pulmonary

On chest x-ray, secondary pulmonary syphilis may be characterized by the following:[4][5][6][7][8]

Cardiac

Chest x-ray is not routinely used to detect thoracic manifestations of syphilis. However, thoracic aortic aneurysms associated with syphilis may be detected incidentally as a widening of the aortic or mediastinal silhouettes on PA and lateral chest x-ray. Accurate assessment of the exact size is difficult and further imaging studies are required to do so.[1][2] Linear calcification of the ascending aorta is an almost pathognomonic finding of syphlitic aortitis.[3]

Bone

X-ray findings may also include osteolytic bone lesions.[9]

References

  1. 1.0 1.1 https://radiopaedia.org/articles/thoracic-aortic-aneurysm. Accessed on September 28th, 2016.
  2. 2.0 2.1 https://radiopaedia.org/articles/ascending-aortic-aneurysm. Accessed on September 28th, 2016.
  3. 3.0 3.1 Dabis R, Radcliffe K (2011). "Is it useful to perform a chest X-ray in asymptomatic patients with late latent syphilis?". Int J STD AIDS. 22 (2): 105–6. doi:10.1258/ijsa.2010.010248. PMID 21427433.
  4. 4.0 4.1 Biro L, Hill AC, Kuflik EG (1968). "Secondary syphilis with unusual clinical and laboratory findings". JAMA. 206 (4): 889–91. PMID 4175712.
  5. 5.0 5.1 David G, Perpoint T, Boibieux A, Pialat JB, Salord H, Devouassoux M; et al. (2006). "Secondary pulmonary syphilis: report of a likely case and literature review". Clin Infect Dis. 42 (3): e11–5. doi:10.1086/499104. PMID 16392072.
  6. 6.0 6.1 Burger HG, Baker HW, Buckler HM, Healy DL, Kovacs GT (1988). "Advances in reproductive medicine: Australian contributions". Aust N Z J Med. 18 (3): 263–77. PMID PMC3056368 : PMC3056368 Check |pmid= value (help).
  7. 7.0 7.1 Coleman DL, McPhee SJ, Ross TF, Naughton JL (1983). "Secondary syphilis with pulmonary involvement". West J Med. 138 (6): 875–8. PMC 1010855. PMID 6613117.
  8. 8.0 8.1 Geer LL, Warshauer DM, Delany DJ (1985). "Pulmonary nodule in secondary syphilis". Australas Radiol. 29 (3): 240–2. PMID 4074225.
  9. 9.0 9.1 Shore RN, Kiesel HA, Bennett HD (1977). "Osteolytic lesions in secondary syphilis". Arch Intern Med. 137 (10): 1465–7. PMID 921426.


Template:WikiDoc Sources