Kawasaki disease causes: Difference between revisions
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*Much research is being performed to discover a definitive [[toxin]] or [[antigen]]ic substance, possibly a [[superantigen]], that is the specific cause of the disease. | *Much research is being performed to discover a definitive [[toxin]] or [[antigen]]ic substance, possibly a [[superantigen]], that is the specific cause of the disease. | ||
*An unknown virus may play a role as an inciting factor as well. | *An unknown virus may play a role as an inciting factor as well. | ||
*There are several hypothesis for the causes of Kawasaki disease, the Infectious agents which are thought to induce kawasaki disease are:<ref name="pmid18448971">{{cite journal |vauthors=Pinna GS, Kafetzis DA, Tselkas OI, Skevaki CL |title=Kawasaki disease: an overview |journal=Curr. Opin. Infect. Dis. |volume=21 |issue=3 |pages=263–70 |date=June 2008 |pmid=18448971 |doi=10.1097/QCO.0b013e3282fbf9cd |url=}}</ref><ref name="pmid9832593">{{cite journal |vauthors=Yanagawa H, Nakamura Y, Yashiro M, Ojima T, Tanihara S, Oki I, Zhang T |title=Results of the nationwide epidemiologic survey of Kawasaki disease in 1995 and 1996 in Japan |journal=Pediatrics |volume=102 |issue=6 |pages=E65 |date=December 1998 |pmid=9832593 |doi= |url=}}</ref> | *There are several hypothesis for the causes of Kawasaki disease, the Infectious agents which are thought to induce kawasaki disease are:<ref name="pmid18448971">{{cite journal |vauthors=Pinna GS, Kafetzis DA, Tselkas OI, Skevaki CL |title=Kawasaki disease: an overview |journal=Curr. Opin. Infect. Dis. |volume=21 |issue=3 |pages=263–70 |date=June 2008 |pmid=18448971 |doi=10.1097/QCO.0b013e3282fbf9cd |url=}}</ref><ref name="pmid9832593">{{cite journal |vauthors=Yanagawa H, Nakamura Y, Yashiro M, Ojima T, Tanihara S, Oki I, Zhang T |title=Results of the nationwide epidemiologic survey of Kawasaki disease in 1995 and 1996 in Japan |journal=Pediatrics |volume=102 |issue=6 |pages=E65 |date=December 1998 |pmid=9832593 |doi= |url=}}</ref><ref name="Sundel2015">{{cite journal|last1=Sundel|first1=Robert P.|title=Kawasaki Disease|journal=Rheumatic Disease Clinics of North America|volume=41|issue=1|year=2015|pages=63–73|issn=0889857X|doi=10.1016/j.rdc.2014.09.010}}</ref> | ||
**[[Parvovirus]] B19 | **[[Parvovirus]] B19 | ||
**[[Meningococcal]] septicemia | **[[Meningococcal]] septicemia | ||
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**[[Rickettsiae|Rickettsia]] species | **[[Rickettsiae|Rickettsia]] species | ||
**[[Tick-borne disease|Tick-borne diseases]] | **[[Tick-borne disease|Tick-borne diseases]] | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 15:48, 2 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]
Overview
The exact cause of kawasaki disease has not been identified. The current etiological theories center primarily on immunological causes for the disease, much research is being performed to discover a definitive toxin or antigenic substance, possibly a superantigen, that is the specific cause of the disease. There are several hypothesis for the causes of Kawasaki disease, the Infectious agents which are thought to induce kawasaki disease are, parvovirus B19, meningococcal septicemia, adenovirus, bacterial toxin–mediated, superantigens, cytomegalovirus, epstein-Barr virus, human lymphotropic virus infection, klebsiella pneumoniae bacteremia, mycoplasma pneumoniae, mite-associated bacteria, measles, propionibacterium acnes, parainfluenza type 3 virus, rotavirus infection, rickettsia species and tick-borne diseases.
Causes
- The exact cause of kawasaki disease has not been identified.
- The current etiological theories center primarily on immunological causes for the disease.
- Much research is being performed to discover a definitive toxin or antigenic substance, possibly a superantigen, that is the specific cause of the disease.
- An unknown virus may play a role as an inciting factor as well.
- There are several hypothesis for the causes of Kawasaki disease, the Infectious agents which are thought to induce kawasaki disease are:[1][2][3]
- Parvovirus B19
- Meningococcal septicemia
- Adenovirus
- Bacterial toxin–mediated superantigens
- Cytomegalovirus
- Epstein-Barr virus
- Human lymphotropic virus infection
- Klebsiella pneumoniae bacteremia
- Mycoplasma pneumoniae
- Mite-associated bacteria
- Measles
- Propionibacterium acnes
- Parainfluenza type 3 virus
- Rotavirus infection
- Rickettsia species
- Tick-borne diseases
References
- ↑ Pinna GS, Kafetzis DA, Tselkas OI, Skevaki CL (June 2008). "Kawasaki disease: an overview". Curr. Opin. Infect. Dis. 21 (3): 263–70. doi:10.1097/QCO.0b013e3282fbf9cd. PMID 18448971.
- ↑ Yanagawa H, Nakamura Y, Yashiro M, Ojima T, Tanihara S, Oki I, Zhang T (December 1998). "Results of the nationwide epidemiologic survey of Kawasaki disease in 1995 and 1996 in Japan". Pediatrics. 102 (6): E65. PMID 9832593.
- ↑ Sundel, Robert P. (2015). "Kawasaki Disease". Rheumatic Disease Clinics of North America. 41 (1): 63–73. doi:10.1016/j.rdc.2014.09.010. ISSN 0889-857X.