Churg-Strauss syndrome history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
*Obtaining a complete history is an important aspect in making a diagnosis of eosinophilic granulomatosis with polyangiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease. | *Obtaining a complete history is an important aspect in making a diagnosis of [[eosinophilic granulomatosis with polyangiitis]]. As it can help differentiate between the [[Anti-neutrophil cytoplasmic antibody|ANCA]] associated [[vasculitis]] and other possible causes that may mimic the [[disease]]. | ||
*Symptoms of eosinophilic granulomatosis with polyangiitis typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be distinguishable.<ref name="pmid6366453">{{cite journal |vauthors=Lanham JG, Elkon KB, Pusey CD, Hughes GR |title=Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome |journal=Medicine (Baltimore) |volume=63 |issue=2 |pages=65–81 |date=March 1984 |pmid=6366453 |doi= |url=}}</ref><ref name="pmid9990352">{{cite journal |vauthors=Guillevin L, Cohen P, Gayraud M, Lhote F, Jarrousse B, Casassus P |title=Churg-Strauss syndrome. Clinical study and long-term follow-up of 96 patients |journal=Medicine (Baltimore) |volume=78 |issue=1 |pages=26–37 |date=January 1999 |pmid=9990352 |doi= |url=}}</ref><ref name="pmid16614512">{{cite journal |vauthors=Oh MJ, Lee JY, Kwon NH, Choi DC |title=Churg-Strauss syndrome: the clinical features and long-term follow-up of 17 patients |journal=J. Korean Med. Sci. |volume=21 |issue=2 |pages=265–71 |date=April 2006 |pmid=16614512 |pmc=2734002 |doi=10.3346/jkms.2006.21.2.265 |url=}}</ref><ref name="pmid25500434">{{cite journal |vauthors=Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M |title=Churg-Strauss syndrome |journal=Autoimmun Rev |volume=14 |issue=4 |pages=341–8 |date=April 2015 |pmid=25500434 |doi=10.1016/j.autrev.2014.12.004 |url=}}</ref> | *[[Symptom|Symptoms]] of [[eosinophilic granulomatosis with polyangiitis]] typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be clinically distinguishable.<ref name="pmid6366453">{{cite journal |vauthors=Lanham JG, Elkon KB, Pusey CD, Hughes GR |title=Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome |journal=Medicine (Baltimore) |volume=63 |issue=2 |pages=65–81 |date=March 1984 |pmid=6366453 |doi= |url=}}</ref><ref name="pmid9990352">{{cite journal |vauthors=Guillevin L, Cohen P, Gayraud M, Lhote F, Jarrousse B, Casassus P |title=Churg-Strauss syndrome. Clinical study and long-term follow-up of 96 patients |journal=Medicine (Baltimore) |volume=78 |issue=1 |pages=26–37 |date=January 1999 |pmid=9990352 |doi= |url=}}</ref><ref name="pmid16614512">{{cite journal |vauthors=Oh MJ, Lee JY, Kwon NH, Choi DC |title=Churg-Strauss syndrome: the clinical features and long-term follow-up of 17 patients |journal=J. Korean Med. Sci. |volume=21 |issue=2 |pages=265–71 |date=April 2006 |pmid=16614512 |pmc=2734002 |doi=10.3346/jkms.2006.21.2.265 |url=}}</ref><ref name="pmid25500434">{{cite journal |vauthors=Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M |title=Churg-Strauss syndrome |journal=Autoimmun Rev |volume=14 |issue=4 |pages=341–8 |date=April 2015 |pmid=25500434 |doi=10.1016/j.autrev.2014.12.004 |url=}}</ref> | ||
**Prodromal phase: Most common manifestations include allergic rhinitis and asthma. | **'''Prodromal phase:''' Most common manifestations include [[Rhinitis|allergic rhinitis]] and [[asthma]]. | ||
**Eosinophilic phase: This phase is characterized by peripheral eosinophilia and infiltration of eosinophils in multiple organs. Most commonly involved organs are lung and GI tract. | **'''Eosinophilic phase:''' This phase is characterized by [[Eosinophilia|peripheral eosinophilia]] and infiltration of [[Eosinophil granulocyte|eosinophils]] in multiple organs. Most commonly involved organs are [[lung]] and [[Gastrointestinal tract|GI tract]]. | ||
**Vasculitic phase: This phase is characterized by small and medium-sized vasculitis and inflammatory granuloma formation. Granulomas can be either vascular or extravascular. Commonly involved organs include lungs, kidneys, skin and peripheral nerves. | **'''Vasculitic phase:''' This phase is characterized by small and medium-sized [[vasculitis]] and inflammatory granuloma formation. Granulomas can be either vascular or extravascular. Commonly involved organs include [[Lung|lungs]], [[Kidney|kidneys]], [[skin]], [[heart]], and [[Peripheral nervous system|peripheral nerves]]. | ||
===History=== | ===History=== | ||
Revision as of 14:29, 4 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [3]
Overview
The majority of patients with [disease name] are asymptomatic.
OR
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
- Obtaining a complete history is an important aspect in making a diagnosis of eosinophilic granulomatosis with polyangiitis. As it can help differentiate between the ANCA associated vasculitis and other possible causes that may mimic the disease.
- Symptoms of eosinophilic granulomatosis with polyangiitis typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be clinically distinguishable.[1][2][3][4]
- Prodromal phase: Most common manifestations include allergic rhinitis and asthma.
- Eosinophilic phase: This phase is characterized by peripheral eosinophilia and infiltration of eosinophils in multiple organs. Most commonly involved organs are lung and GI tract.
- Vasculitic phase: This phase is characterized by small and medium-sized vasculitis and inflammatory granuloma formation. Granulomas can be either vascular or extravascular. Commonly involved organs include lungs, kidneys, skin, heart, and peripheral nerves.
History
Patients with [disease name]] may have a positive history of:
- [History finding 1]
- [History finding 2]
- [History finding 3]
Common Symptoms
Common symptoms of [disease] include:
- [Symptom 1]
- [Symptom 2]
- [Symptom 3]
Less Common Symptoms
Less common symptoms of [disease name] include
- [Symptom 1]
- [Symptom 2]
- [Symptom 3]
References
- ↑ Lanham JG, Elkon KB, Pusey CD, Hughes GR (March 1984). "Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome". Medicine (Baltimore). 63 (2): 65–81. PMID 6366453.
- ↑ Guillevin L, Cohen P, Gayraud M, Lhote F, Jarrousse B, Casassus P (January 1999). "Churg-Strauss syndrome. Clinical study and long-term follow-up of 96 patients". Medicine (Baltimore). 78 (1): 26–37. PMID 9990352.
- ↑ Oh MJ, Lee JY, Kwon NH, Choi DC (April 2006). "Churg-Strauss syndrome: the clinical features and long-term follow-up of 17 patients". J. Korean Med. Sci. 21 (2): 265–71. doi:10.3346/jkms.2006.21.2.265. PMC 2734002. PMID 16614512.
- ↑ Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Ruoppolo G, Altissimi G, De Vincentiis M (April 2015). "Churg-Strauss syndrome". Autoimmun Rev. 14 (4): 341–8. doi:10.1016/j.autrev.2014.12.004. PMID 25500434.