Scleroderma other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
Nail-fold capillaroscopy may be helpful in the diagnosis of scleroderma. Findings on nail-fold capillaroscopy diagnostic of raynaud's phenomenon include nail-fold capillary abnormalities, capillary dilatation, and capillary loop drop-out. | Nail-fold video capillaroscopy (NVC) may be helpful in the diagnosis of scleroderma. Findings on nail-fold video capillaroscopy diagnostic of raynaud's phenomenon (RP) and scleroderma microangiopathy include nail-fold capillary abnormalities, capillary dilatation, and capillary loop drop-out. Findings on nail-fold video capillaroscopy diagnostic of scleroderma microangiopathy are graded into 3 phases; early, active and late. | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
*Nail-fold capillaroscopy may be helpful in the diagnosis of scleroderma. Findings on nail-fold capillaroscopy diagnostic of raynaud's phenomenon include:<ref name="pmid14613262">{{cite journal |vauthors=Cutolo M, Grassi W, Matucci Cerinic M |title=Raynaud's phenomenon and the role of capillaroscopy |journal=Arthritis Rheum. |volume=48 |issue=11 |pages=3023–30 |date=November 2003 |pmid=14613262 |doi=10.1002/art.11310 |url=}}</ref> | *Nail-fold capillaroscopy may be helpful in the diagnosis of scleroderma. Findings on nail-fold capillaroscopy diagnostic of raynaud's phenomenon (RP) include:<ref name="pmid14613262">{{cite journal |vauthors=Cutolo M, Grassi W, Matucci Cerinic M |title=Raynaud's phenomenon and the role of capillaroscopy |journal=Arthritis Rheum. |volume=48 |issue=11 |pages=3023–30 |date=November 2003 |pmid=14613262 |doi=10.1002/art.11310 |url=}}</ref> | ||
**Nail-fold capillary abnormalities | **Nail-fold capillary abnormalities | ||
**Capillary dilatation | **Capillary dilatation | ||
**Capillary loop drop-out | **Capillary loop drop-out | ||
*Nail-fold capillaroscopy: | *Nail-fold capillaroscopy: | ||
**Non-invasive technique that facilitates in vivo assessment of cutaneous microvasculature | **Non-invasive technique that facilitates in vivo assessment of cutaneous microvasculature and microvascular damage in scleroderma patients | ||
*Findings on nail-fold video capillaroscopy diagnostic of scleroderma microangiopathy are graded into 3 phases:<ref name="pmid10648032">{{cite journal |vauthors=Cutolo M, Sulli A, Pizzorni C, Accardo S |title=Nailfold videocapillaroscopy assessment of microvascular damage in systemic sclerosis |journal=J. Rheumatol. |volume=27 |issue=1 |pages=155–60 |date=January 2000 |pmid=10648032 |doi= |url=}}</ref><ref name="pmid18078610">{{cite journal |vauthors=Cutolo M, Matucci Cerinic M |title=Nailfold capillaroscopy and classification criteria for systemic sclerosis |journal=Clin. Exp. Rheumatol. |volume=25 |issue=5 |pages=663–5 |date=2007 |pmid=18078610 |doi= |url=}}</ref><ref name="pmid18037628">{{cite journal |vauthors=Sulli A, Secchi ME, Pizzorni C, Cutolo M |title=Scoring the nailfold microvascular changes during the capillaroscopic analysis in systemic sclerosis patients |journal=Ann. Rheum. Dis. |volume=67 |issue=6 |pages=885–7 |date=June 2008 |pmid=18037628 |doi=10.1136/ard.2007.079756 |url=}}</ref> | |||
**Early: | |||
***Giant capillaries | |||
***Hemorrhages | |||
***These findings facilitate early diagnosis of scleroderma and facilitate differentiation between primary and secondary RP | |||
**Active | |||
***The microangiopathy changes in the early phase are more evident in the active phase | |||
**Late | |||
***Severe loss of capillaries | |||
***Vascular architectural disorganization | |||
***Presence of ramified or bushy capillaries | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
Nail-fold video capillaroscopy (NVC) may be helpful in the diagnosis of scleroderma. Findings on nail-fold video capillaroscopy diagnostic of raynaud's phenomenon (RP) and scleroderma microangiopathy include nail-fold capillary abnormalities, capillary dilatation, and capillary loop drop-out. Findings on nail-fold video capillaroscopy diagnostic of scleroderma microangiopathy are graded into 3 phases; early, active and late.
Other Imaging Findings
- Nail-fold capillaroscopy may be helpful in the diagnosis of scleroderma. Findings on nail-fold capillaroscopy diagnostic of raynaud's phenomenon (RP) include:[1]
- Nail-fold capillary abnormalities
- Capillary dilatation
- Capillary loop drop-out
- Nail-fold capillaroscopy:
- Non-invasive technique that facilitates in vivo assessment of cutaneous microvasculature and microvascular damage in scleroderma patients
- Findings on nail-fold video capillaroscopy diagnostic of scleroderma microangiopathy are graded into 3 phases:[2][3][4]
- Early:
- Giant capillaries
- Hemorrhages
- These findings facilitate early diagnosis of scleroderma and facilitate differentiation between primary and secondary RP
- Active
- The microangiopathy changes in the early phase are more evident in the active phase
- Late
- Severe loss of capillaries
- Vascular architectural disorganization
- Presence of ramified or bushy capillaries
- Early:
References
- ↑ Cutolo M, Grassi W, Matucci Cerinic M (November 2003). "Raynaud's phenomenon and the role of capillaroscopy". Arthritis Rheum. 48 (11): 3023–30. doi:10.1002/art.11310. PMID 14613262.
- ↑ Cutolo M, Sulli A, Pizzorni C, Accardo S (January 2000). "Nailfold videocapillaroscopy assessment of microvascular damage in systemic sclerosis". J. Rheumatol. 27 (1): 155–60. PMID 10648032.
- ↑ Cutolo M, Matucci Cerinic M (2007). "Nailfold capillaroscopy and classification criteria for systemic sclerosis". Clin. Exp. Rheumatol. 25 (5): 663–5. PMID 18078610.
- ↑ Sulli A, Secchi ME, Pizzorni C, Cutolo M (June 2008). "Scoring the nailfold microvascular changes during the capillaroscopic analysis in systemic sclerosis patients". Ann. Rheum. Dis. 67 (6): 885–7. doi:10.1136/ard.2007.079756. PMID 18037628.