Adult-onset Still's disease classification: Difference between revisions
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==Classification== | ==Classification== | ||
=== Classification based on clinical presentation === | |||
Adult-onset Stiil's disease (AOSD) may be classified based on the predominant clinical picture with which the patient presents. The following are the sub-types:<ref name="pmid15642140">{{cite journal |vauthors=Villanueva J, Lee S, Giannini EH, Graham TB, Passo MH, Filipovich A, Grom AA |title=Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome |journal=Arthritis Res. Ther. |volume=7 |issue=1 |pages=R30–7 |date=2005 |pmid=15642140 |pmc=1064882 |doi=10.1186/ar1453 |url=}}</ref> | |||
* ASOD with pre-dominant systemic symptoms | |||
* ASOD with pre-dominant arthritis | |||
{| class="wikitable" | |||
! rowspan="5" |Adult-onset Still's disease sub-types | |||
! rowspan="3" |Systemic sub-type | |||
! colspan="5" |Distinguishing features | |||
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!Pre-dominant cellular mechanism | |||
!Clinical presentation | |||
!Cytokine profile | |||
!Response to treatment | |||
!Miscellaneous | |||
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* Natural killer (NK) cell dysfunction (deficiency) | |||
* CD8 type (cytotoxic) T cell dysfunction (deficiency) | |||
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! rowspan="2" |Arthritis sub-type | |||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 23:13, 7 April 2018
Template:Adult-onset Still's disease
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Classification
Classification based on clinical presentation
Adult-onset Stiil's disease (AOSD) may be classified based on the predominant clinical picture with which the patient presents. The following are the sub-types:[1]
- ASOD with pre-dominant systemic symptoms
- ASOD with pre-dominant arthritis
| Adult-onset Still's disease sub-types | Systemic sub-type | Distinguishing features | ||||
|---|---|---|---|---|---|---|
| Pre-dominant cellular mechanism | Clinical presentation | Cytokine profile | Response to treatment | Miscellaneous | ||
|
||||||
| Arthritis sub-type | ||||||
References
- ↑ Villanueva J, Lee S, Giannini EH, Graham TB, Passo MH, Filipovich A, Grom AA (2005). "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome". Arthritis Res. Ther. 7 (1): R30–7. doi:10.1186/ar1453. PMC 1064882. PMID 15642140.