Reactive arthritis laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings consistent with the diagnosis of reactive arthritis include: | Laboratory findings consistent with the diagnosis of reactive arthritis include:<ref name="pmid15084505">{{cite journal |vauthors=Colmegna I, Cuchacovich R, Espinoza LR |title=HLA-B27-associated reactive arthritis: pathogenetic and clinical considerations |journal=Clin. Microbiol. Rev. |volume=17 |issue=2 |pages=348–69 |date=April 2004 |pmid=15084505 |pmc=387405 |doi= |url=}}</ref><ref name="pmid8835566">{{cite journal |vauthors=Locht H, Peen E, Skogh T |title=Antineutrophil cytoplasmic antibodies in reactive arthritis |journal=J. Rheumatol. |volume=22 |issue=12 |pages=2304–6 |date=December 1995 |pmid=8835566 |doi= |url=}}</ref> | ||
*Elevated ESR | *Elevated ESR | ||
*Elevated C-reactive protein | *Elevated C-reactive protein | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory findings consistent with the diagnosis of reactive arthritis include elevated ESR, elevated C-reactive protein, and elevated TLC showing increased PMNs. Synovial fluid or synovial membrane biopsy for detection of bacterial DNA by PCR or immunofluorescence microscopy.
Laboratory Findings
Laboratory findings consistent with the diagnosis of reactive arthritis include:[1][2]
- Elevated ESR
- Elevated C-reactive protein
- Elevated TLC showing increased PMNs
- Synovial fluid analysis to determine cell count, culture, glucose, and presence of crystals.
- Diagnostic lab evaluations include testing for HLA-B27, PCR or ELISA for reactive arthritis associated microorganisms.
- Laboratory evaluations required to establish infection with reactive arthritis causing organisms include routine urine exam, culture of stool and urethra.
- Synovial fluid or synovial membrane biopsy for detection of bacterial DNA by PCR or immunofluorescence microscopy.
- IgA antibodies to specific bacterial antigens
- Other test include tuberculin skin test and HIV.
References
- ↑ Colmegna I, Cuchacovich R, Espinoza LR (April 2004). "HLA-B27-associated reactive arthritis: pathogenetic and clinical considerations". Clin. Microbiol. Rev. 17 (2): 348–69. PMC 387405. PMID 15084505.
- ↑ Locht H, Peen E, Skogh T (December 1995). "Antineutrophil cytoplasmic antibodies in reactive arthritis". J. Rheumatol. 22 (12): 2304–6. PMID 8835566.