Restless legs syndrome laboratory findings: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 10: | Line 10: | ||
*As restless leg syndrome may be secondary to iron deficiency or [[kidney diseases]], all patients should be screened for iron deficiency | *As restless leg syndrome may be secondary to iron deficiency or [[kidney diseases]] or thyroid diseases, all patients should be screened for iron deficiency, [[kidney diseases]] and thyroid diseases. | ||
* Iron studies usually done for detecting iron deficiency anemia are:<ref name="pmid21694802">{{cite journal| author=Johnson-Wimbley TD, Graham DY| title=Diagnosis and management of iron deficiency anemia in the 21st century. | journal=Therap Adv Gastroenterol | year= 2011 | volume= 4 | issue= 3 | pages= 177-84 | pmid=21694802 | doi=10.1177/1756283X11398736 | pmc=3105608 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21694802 }} </ref> | * Iron studies usually done for detecting iron deficiency anemia in patients with restless leg syndrome usually are:<ref name="pmid21694802">{{cite journal| author=Johnson-Wimbley TD, Graham DY| title=Diagnosis and management of iron deficiency anemia in the 21st century. | journal=Therap Adv Gastroenterol | year= 2011 | volume= 4 | issue= 3 | pages= 177-84 | pmid=21694802 | doi=10.1177/1756283X11398736 | pmc=3105608 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21694802 }} </ref> | ||
** [[Serum iron]]- Decreased in iron deficiency | ** [[Serum iron]]- Decreased in iron deficiency | ||
** [[Transferrin]]- Elevated in iron deficiency | ** [[Transferrin]]- Elevated in iron deficiency | ||
| Line 17: | Line 17: | ||
** [[Transferrin saturation]]- derived by dividing the serum iron by the TIBC. Decreased in iron deficiency | ** [[Transferrin saturation]]- derived by dividing the serum iron by the TIBC. Decreased in iron deficiency | ||
** [[Ferritin]]- Indicator of body iron stores and is low in iron deficiency. However, ferritin also acts as an [[acute phase reactant]] and can be unreliable in inflammatory illness | ** [[Ferritin]]- Indicator of body iron stores and is low in iron deficiency. However, ferritin also acts as an [[acute phase reactant]] and can be unreliable in inflammatory illness | ||
* [[Kidney function|kidney function tests]] which usually done for detecting [[kidney diseases]] are: | * [[Kidney function|kidney function tests]] which usually done for detecting [[kidney diseases]] in patients with restless leg syndrome usually are:<ref name="pmid24247595">{{cite journal| author=Gade K, Blaschke S, Rodenbeck A, Becker A, Anderson-Schmidt H, Cohrs S| title=Uremic restless legs syndrome (RLS) and sleep quality in patients with end-stage renal disease on hemodialysis: potential role of homocysteine and parathyroid hormone. | journal=Kidney Blood Press Res | year= 2013 | volume= 37 | issue= 4-5 | pages= 458-63 | pmid=24247595 | doi=10.1159/000355727 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24247595 }} </ref> | ||
** Blood urea nitrogen (BUN) | ** Blood urea nitrogen (BUN) | ||
** Creatinine | ** Creatinine | ||
[[thyroid function tests]] which usually done for detecting [[kidney diseases]] in patients with restless leg syndrome usually are:<ref name="pmid20535374">{{cite journal| author=Pereira JC, Pradella-Hallinan M, Lins Pessoa Hd| title=Imbalance between thyroid hormones and the dopaminergic system might be central to the pathophysiology of restless legs syndrome: a hypothesis. | journal=Clinics (Sao Paulo) | year= 2010 | volume= 65 | issue= 5 | pages= 548-54 | pmid=20535374 | doi=10.1590/S1807-59322010000500013 | pmc=2882550 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20535374 }} </ref> | |||
==References== | ==References== | ||
Revision as of 19:53, 10 April 2018
|
Restless legs syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Restless legs syndrome laboratory findings On the Web |
|
American Roentgen Ray Society Images of Restless legs syndrome laboratory findings |
|
Risk calculators and risk factors for Restless legs syndrome laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
laboratory findings are usually normal for patients with restless leg syndrome.
Laboratory Findings
- As restless leg syndrome may be secondary to iron deficiency or kidney diseases or thyroid diseases, all patients should be screened for iron deficiency, kidney diseases and thyroid diseases.
- Iron studies usually done for detecting iron deficiency anemia in patients with restless leg syndrome usually are:[1]
- Serum iron- Decreased in iron deficiency
- Transferrin- Elevated in iron deficiency
- Total iron binding capacity (TIBC)- Elevated in iron deficiency
- Transferrin saturation- derived by dividing the serum iron by the TIBC. Decreased in iron deficiency
- Ferritin- Indicator of body iron stores and is low in iron deficiency. However, ferritin also acts as an acute phase reactant and can be unreliable in inflammatory illness
- kidney function tests which usually done for detecting kidney diseases in patients with restless leg syndrome usually are:[2]
- Blood urea nitrogen (BUN)
- Creatinine
thyroid function tests which usually done for detecting kidney diseases in patients with restless leg syndrome usually are:[3]
References
- ↑ Johnson-Wimbley TD, Graham DY (2011). "Diagnosis and management of iron deficiency anemia in the 21st century". Therap Adv Gastroenterol. 4 (3): 177–84. doi:10.1177/1756283X11398736. PMC 3105608. PMID 21694802.
- ↑ Gade K, Blaschke S, Rodenbeck A, Becker A, Anderson-Schmidt H, Cohrs S (2013). "Uremic restless legs syndrome (RLS) and sleep quality in patients with end-stage renal disease on hemodialysis: potential role of homocysteine and parathyroid hormone". Kidney Blood Press Res. 37 (4–5): 458–63. doi:10.1159/000355727. PMID 24247595.
- ↑ Pereira JC, Pradella-Hallinan M, Lins Pessoa Hd (2010). "Imbalance between thyroid hormones and the dopaminergic system might be central to the pathophysiology of restless legs syndrome: a hypothesis". Clinics (Sao Paulo). 65 (5): 548–54. doi:10.1590/S1807-59322010000500013. PMC 2882550. PMID 20535374.