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==Overview==
==Overview==
Crystal induced arthritis is a relatively common condition that involves deposition of crystals in joints and soft tissues. A variety of crystals can deposit in and around joints and soft tissues, resulting in articular and periarticular inflammation. Monosodium urate (MSU) and calcium pyrophosphate dihydrate (CPPD) are the most commonly involved crystals in the pathogenesis of crystal induced arthropathies. Other rare types of crystal arthropathy include hydroxyapatite crystal deposition arthropathy. Gout and pseudo-gout manifest with similar symptoms, and cannot be distinguished clinically.  Synovial fluid analysis the involved joint is essential to diagnose and differentiation of crystal induced arthropathies.  
Crystal induced arthritis is a relatively common condition that involves deposition of crystals in [[Joint|joints]] and soft tissues. A variety of crystals can deposit in and around [[Joint|joints]] and soft tissues, resulting in [[articular]] and periarticular inflammation. Monosodium urate (MSU) and calcium pyrophosphate dihydrate (CPPD) are the most commonly involved crystals in the pathogenesis of crystal induced [[Arthropathy|arthropathies]]. Other rare types of crystal arthropathy include [[Hydroxylapatite|hydroxyapatite]] crystal deposition [[arthropathy]]. [[Gout]] and [[Pseudogout|pseudo-gout]] manifest with similar symptoms, and cannot be distinguished clinically.  [[Synovial fluid]] analysis the involved joint is essential to diagnose and differentiation of crystal induced arthropathies.  


==Causes==
==Causes==
*[[Gout]]
*[[Pseudogout]] (Calcium pyrophosphate dihydrate)
*[[Calcium apatite deposition disease]]
==Classification==
==Classification==
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Revision as of 15:55, 23 April 2018

Crystal arthritis Main page

Patient Information

Gout (patient information)
Pseudogout (patient information)

Overview

Causes

Classification

Gout
Pseudogout

Differentiating Gout from Pseudogout

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Crystal induced arthritis is a relatively common condition that involves deposition of crystals in joints and soft tissues. A variety of crystals can deposit in and around joints and soft tissues, resulting in articular and periarticular inflammation. Monosodium urate (MSU) and calcium pyrophosphate dihydrate (CPPD) are the most commonly involved crystals in the pathogenesis of crystal induced arthropathies. Other rare types of crystal arthropathy include hydroxyapatite crystal deposition arthropathy. Gout and pseudo-gout manifest with similar symptoms, and cannot be distinguished clinically. Synovial fluid analysis the involved joint is essential to diagnose and differentiation of crystal induced arthropathies.

Causes

Classification

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Arthritis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Inflammatory
 
 
 
 
 
 
 
 
 
Non-Inflammatory
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Osteoarthritis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Rheumatoid factor
 
 
 
Infectious
 
 
 
Crystalloid
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Rheumatoid positive
 
 
 
 
 
Rheumatoid negative
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
RA
Lupus
Scleroderma
 
 
 
 
 
AKS
Psoriatic arthritis
Reactive arthritis
 
Gout
 
Pseudogout
 
Calcium hydroxapatite crystals
 
 

Differentiating Crystal arthritis from other diseases