Adult-onset Still's disease history and symptoms: Difference between revisions
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=== Common symptoms === | === Common symptoms === | ||
The common symptoms of AOSD include the following:<ref name="pmid16219707">{{cite journal |vauthors=Efthimiou P, Paik PK, Bielory L |title=Diagnosis and management of adult onset Still's disease |journal=Ann. Rheum. Dis. |volume=65 |issue=5 |pages=564–72 |date=May 2006 |pmid=16219707 |pmc=1798146 |doi=10.1136/ard.2005.042143 |url=}}</ref> | The common symptoms of AOSD include the following:<ref name="pmid16219707">{{cite journal |vauthors=Efthimiou P, Paik PK, Bielory L |title=Diagnosis and management of adult onset Still's disease |journal=Ann. Rheum. Dis. |volume=65 |issue=5 |pages=564–72 |date=May 2006 |pmid=16219707 |pmc=1798146 |doi=10.1136/ard.2005.042143 |url=}}</ref><ref name="pmid3659248">{{cite journal |vauthors=Wouters JM, van de Putte LB |title=Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases |journal=Q. J. Med. |volume=61 |issue=235 |pages=1055–65 |date=November 1986 |pmid=3659248 |doi= |url=}}</ref> | ||
* Spiking fever greater than equal to 39 C for greater than equal to 1 week | * Spiking fever greater than equal to 39 C for greater than equal to 1 week | ||
* Arthralgia for greater than equal to 2 weeks | * Arthralgia for greater than equal to 2 weeks | ||
Revision as of 13:34, 17 April 2018
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Adult-onset Still's disease |
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Differentiating Adult-onset Still’s Disease from other Diseases |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
History
Age of onset
- The typical age of onset of adult-onset Still's disease (AOSD) is between 16 to 35 years of age.
Family history
- Adult onset Still's disease (AOSD) is not a genetic/hereditary condition but it is known to be associated with various HLA alleles.
Initial presentation
- A patient suffering from AOSD may present with a fever greater than equal to 39 C for greater than equal to 1 week along with associated arthralgia/arthritis for greater than equal to 2 weeks. There may be a maculopapular non-pruritic rash on the trunk or limbs. Patients may also complain of sore throat and lymphadenopathy. Physicians should rule out other causes of fever and arthralgia for example, septic arthritis, rheumatoid arthritis, drug reaction and malignancy.
Past medical history
- The symptoms of AOSD evolve over a period of weeks.
Symptoms
Common symptoms
The common symptoms of AOSD include the following:[1][2]
- Spiking fever greater than equal to 39 C for greater than equal to 1 week
- Arthralgia for greater than equal to 2 weeks
- Maculopapular non-pruritic rash on the trunk or limbs
- Sore throat
- Lymphadenopathy
Less common symptoms
Less common symptoms of AOSD include the following:
- Myalgias
- Dyspnea
- Edema
- Soft tissue swelling
References
- ↑ Efthimiou P, Paik PK, Bielory L (May 2006). "Diagnosis and management of adult onset Still's disease". Ann. Rheum. Dis. 65 (5): 564–72. doi:10.1136/ard.2005.042143. PMC 1798146. PMID 16219707.
- ↑ Wouters JM, van de Putte LB (November 1986). "Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases". Q. J. Med. 61 (235): 1055–65. PMID 3659248.