Parkinson's disease MRI: Difference between revisions
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==MRI== | ==MRI== | ||
In the STN of PD patients there are increased amount of iron. The excess iron will cause a reduction in T2 relaxation time and it’s more prominent in one side. | In the STN of PD patients there are increased amount of iron. The excess iron will cause a reduction in T2 relaxation time and it’s more prominent in one side.<ref name="pmid15981079">{{cite journal |vauthors=Kosta P, Argyropoulou MI, Markoula S, Konitsiotis S |title=MRI evaluation of the basal ganglia size and iron content in patients with Parkinson's disease |journal=J. Neurol. |volume=253 |issue=1 |pages=26–32 |date=January 2006 |pmid=15981079 |doi=10.1007/s00415-005-0914-9 |url=}}</ref> There are also evidence of reduced iron content in putamen and GPe.<ref name="pmid11099445">{{cite journal |vauthors=Graham JM, Paley MN, Grünewald RA, Hoggard N, Griffiths PD |title=Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence |journal=Brain |volume=123 Pt 12 |issue= |pages=2423–31 |date=December 2000 |pmid=11099445 |doi= |url=}}</ref><ref name="pmid7763206">{{cite journal |vauthors=Ryvlin P, Broussolle E, Piollet H, Viallet F, Khalfallah Y, Chazot G |title=Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease |journal=Arch. Neurol. |volume=52 |issue=6 |pages=583–8 |date=June 1995 |pmid=7763206 |doi= |url=}}</ref> | ||
==References== | ==References== | ||
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Overview
MRI
In the STN of PD patients there are increased amount of iron. The excess iron will cause a reduction in T2 relaxation time and it’s more prominent in one side.[1] There are also evidence of reduced iron content in putamen and GPe.[2][3]
References
- ↑ Kosta P, Argyropoulou MI, Markoula S, Konitsiotis S (January 2006). "MRI evaluation of the basal ganglia size and iron content in patients with Parkinson's disease". J. Neurol. 253 (1): 26–32. doi:10.1007/s00415-005-0914-9. PMID 15981079.
- ↑ Graham JM, Paley MN, Grünewald RA, Hoggard N, Griffiths PD (December 2000). "Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence". Brain. 123 Pt 12: 2423–31. PMID 11099445.
- ↑ Ryvlin P, Broussolle E, Piollet H, Viallet F, Khalfallah Y, Chazot G (June 1995). "Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease". Arch. Neurol. 52 (6): 583–8. PMID 7763206.