Parkinson's disease other diagnostic studies: Difference between revisions
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'''Response to dopaminergic therapy:''' One of the useful methods in diagnosing [[Parkinson's disease|PD]] is patient response to dopaminergic therapy. [[Levodopa]] and [[apomorphine]] challenge tests in proven to be useful in distinguishing [[Parkinson's disease|PD]] from other parkinsonian syndromes.<ref name="pmid16606907">{{cite journal |vauthors=Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ |title=Practice Parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology |journal=Neurology |volume=66 |issue=7 |pages=968–75 |date=April 2006 |pmid=16606907 |doi=10.1212/01.wnl.0000215437.80053.d0 |url=}}</ref> | '''Response to dopaminergic therapy:''' One of the useful methods in diagnosing [[Parkinson's disease|PD]] is patient response to dopaminergic therapy. [[Levodopa]] and [[apomorphine]] challenge tests in proven to be useful in distinguishing [[Parkinson's disease|PD]] from other parkinsonian syndromes.<ref name="pmid16606907">{{cite journal |vauthors=Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ |title=Practice Parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology |journal=Neurology |volume=66 |issue=7 |pages=968–75 |date=April 2006 |pmid=16606907 |doi=10.1212/01.wnl.0000215437.80053.d0 |url=}}</ref> | ||
'''Autonomic testing:''' Autonomic testing including cardiac sympathetic denervation, urodynamic testing, anal or urethral EMG, sympathetic skin responses, quantitative sudomotor axon reflex test, [[tilt table test]] and heart rate variability during forced respirations are also useful in diagnosing [[Parkinson's disease|PD]]. | '''Autonomic testing:''' Autonomic testing including cardiac sympathetic denervation, urodynamic testing, anal or urethral EMG, sympathetic skin responses, quantitative sudomotor axon reflex test, [[tilt table test]] and heart rate variability during forced respirations are also useful in diagnosing [[Parkinson's disease|PD]].<ref name="pmid16606907">{{cite journal |vauthors=Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ |title=Practice Parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology |journal=Neurology |volume=66 |issue=7 |pages=968–75 |date=April 2006 |pmid=16606907 |doi=10.1212/01.wnl.0000215437.80053.d0 |url=}}</ref><ref name="pmid22321865">{{cite journal |vauthors=Orimo S, Suzuki M, Inaba A, Mizusawa H |title=123I-MIBG myocardial scintigraphy for differentiating Parkinson's disease from other neurodegenerative parkinsonism: a systematic review and meta-analysis |journal=Parkinsonism Relat. Disord. |volume=18 |issue=5 |pages=494–500 |date=June 2012 |pmid=22321865 |doi=10.1016/j.parkreldis.2012.01.009 |url=}}</ref> | ||
'''Olfactory testing:''' | '''Olfactory testing:''' |
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Overview
Other diagnostic studies
Response to dopaminergic therapy: One of the useful methods in diagnosing PD is patient response to dopaminergic therapy. Levodopa and apomorphine challenge tests in proven to be useful in distinguishing PD from other parkinsonian syndromes.[1]
Autonomic testing: Autonomic testing including cardiac sympathetic denervation, urodynamic testing, anal or urethral EMG, sympathetic skin responses, quantitative sudomotor axon reflex test, tilt table test and heart rate variability during forced respirations are also useful in diagnosing PD.[1][2]
Olfactory testing:
References
- ↑ 1.0 1.1 Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ (April 2006). "Practice Parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology". Neurology. 66 (7): 968–75. doi:10.1212/01.wnl.0000215437.80053.d0. PMID 16606907.
- ↑ Orimo S, Suzuki M, Inaba A, Mizusawa H (June 2012). "123I-MIBG myocardial scintigraphy for differentiating Parkinson's disease from other neurodegenerative parkinsonism: a systematic review and meta-analysis". Parkinsonism Relat. Disord. 18 (5): 494–500. doi:10.1016/j.parkreldis.2012.01.009. PMID 22321865.