Chondroma natural history: Difference between revisions
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==Complications== | ==Complications== | ||
Common complications of chondroma include:<ref name= | Common complications of chondroma include:<ref name="pmid3197353">{{cite journal |vauthors=Palaoglu S, Akkas O, Sav A |title=Chondroma of the cervical spine |journal=Clin Neurol Neurosurg |volume=90 |issue=3 |pages=253–5 |date=1988 |pmid=3197353 |doi= |url=}}</ref><ref name="pmid15285552">{{cite journal |vauthors=Müller PE, Dürr HR, Nerlich A, Pellengahr C, Maier M, Jansson V |title=Malignant transformation of a benign enchondroma of the hand to secondary chondrosarcoma with isolated pulmonary metastasis |journal=Acta Chir. Belg. |volume=104 |issue=3 |pages=341–4 |date=June 2004 |pmid=15285552 |doi= |url=}}</ref><ref name="pmid12354749">{{cite journal |vauthors=Martin JA, Forest E, Block JA, Klingelhutz AJ, Whited B, Gitelis S, Wilkey A, Buckwalter JA |title=Malignant transformation in human chondrosarcoma cells supported by telomerase activation and tumor suppressor inactivation |journal=Cell Growth Differ. |volume=13 |issue=9 |pages=397–407 |date=September 2002 |pmid=12354749 |doi= |url=}}</ref><ref name="pmid21053879">{{cite journal |vauthors=Choi E, Wert M, Guerrieri C, Tucci J |title=A pathologic fracture of an intracortical chondroma masking as an osteoid osteoma |journal=Orthopedics |volume=33 |issue=11 |pages=845 |date=November 2010 |pmid=21053879 |doi=10.3928/01477447-20100924-24 |url=}}</ref> | ||
*[[Malignant]] transformation into a low grade chondrosarcoma | *[[Malignant]] transformation into a low grade chondrosarcoma | ||
*Growth disturbance | *Growth disturbance | ||
Revision as of 19:23, 18 April 2018
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Chondroma Microchapters |
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Treatment |
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Chondroma natural history On the Web |
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American Roentgen Ray Society Images of Chondroma natural history |
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Risk calculators and risk factors for Chondroma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
If left untreated, patients with chondroma may progress to develop pain and discomfort. Common complications of chondroma include malignant transformation into a low grade chondrosarcoma, pathologic fractures, and skeletal deformities.[1] Common complications of chondroma include malignant transformation into a low grade chondrosarcoma, pathologic fractures, and skeletal deformities.[1][2][3] Prognosis is generally good for benign chondromas.[1]
Natural History
If left untreated, patients with chondroma may progress to develop pain and discomfort. If an enchondroma is painful in the absence of a fracture, it should be considered malignant unless proven otherwise.[1]
Complications
Common complications of chondroma include:[4][5][6][7]
- Malignant transformation into a low grade chondrosarcoma
- Growth disturbance
- Pathologic fracture, especially in short tubular
- Recurrence
Prognosis
Prognosis is generally good for benign chondromas.[1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Enchondroma. Radiopedia. http://radiopaedia.org/articles/enchondroma Accessed on December 21, 2015
- ↑ Maffucci syndrome. Wikipedia. Accessed on December 21, 2015https://en.wikipedia.org/wiki/Maffucci_syndrome
- ↑ Ollier disease. Wikipedia. https://en.wikipedia.org/wiki/Ollier_disease Accessed on December 21, 2015.
- ↑ Palaoglu S, Akkas O, Sav A (1988). "Chondroma of the cervical spine". Clin Neurol Neurosurg. 90 (3): 253–5. PMID 3197353.
- ↑ Müller PE, Dürr HR, Nerlich A, Pellengahr C, Maier M, Jansson V (June 2004). "Malignant transformation of a benign enchondroma of the hand to secondary chondrosarcoma with isolated pulmonary metastasis". Acta Chir. Belg. 104 (3): 341–4. PMID 15285552.
- ↑ Martin JA, Forest E, Block JA, Klingelhutz AJ, Whited B, Gitelis S, Wilkey A, Buckwalter JA (September 2002). "Malignant transformation in human chondrosarcoma cells supported by telomerase activation and tumor suppressor inactivation". Cell Growth Differ. 13 (9): 397–407. PMID 12354749.
- ↑ Choi E, Wert M, Guerrieri C, Tucci J (November 2010). "A pathologic fracture of an intracortical chondroma masking as an osteoid osteoma". Orthopedics. 33 (11): 845. doi:10.3928/01477447-20100924-24. PMID 21053879.