Amyloidosis natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
* The median survival of patients with AL amyloidosis is aproximately 3.8 years. | * The median survival of patients with AL amyloidosis is aproximately 3.8 years.<ref name="pmid21483018">{{cite journal |vauthors=Merlini G, Seldin DC, Gertz MA |title=Amyloidosis: pathogenesis and new therapeutic options |journal=J. Clin. Oncol. |volume=29 |issue=14 |pages=1924–33 |date=May 2011 |pmid=21483018 |pmc=3138545 |doi=10.1200/JCO.2010.32.2271 |url=}}</ref> | ||
* In AL amyloidosis 27% of patients dying within 1 year from diagnosis. | * In AL amyloidosis 27% of patients dying within 1 year from diagnosis. | ||
* The major determinant of outcome in amyloidosis is the extent of cardiac involvement. | * The major determinant of outcome in amyloidosis is the extent of cardiac involvement. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
Natural History
Complications
Prognosis
- The median survival of patients with AL amyloidosis is aproximately 3.8 years.[1]
- In AL amyloidosis 27% of patients dying within 1 year from diagnosis.
- The major determinant of outcome in amyloidosis is the extent of cardiac involvement.
- Cardiac amyloidosis is the cause of death in 75% of the patients who died, including sudden death in 25%.
References
- ↑ Merlini G, Seldin DC, Gertz MA (May 2011). "Amyloidosis: pathogenesis and new therapeutic options". J. Clin. Oncol. 29 (14): 1924–33. doi:10.1200/JCO.2010.32.2271. PMC 3138545. PMID 21483018.