Nephrotic syndrome classification: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Nephrotic syndrome}} | {{Nephrotic syndrome}} | ||
{{CMG}} {{APM}}; {{AE}} {{OO}} [[User:YazanDaaboul|Yazan Daaboul]], [[User:Sergekorjian|Serge Korjian]] | {{CMG}} {{APM}}; {{AE}} {{OO}} [[User:YazanDaaboul|Yazan Daaboul]], | ||
[[User:Sergekorjian|Serge Korjian]] | |||
==Overview== | ==Overview== | ||
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==Classification== | ==Classification== | ||
===Etiologic Classification=== | ===Etiologic Classification=== | ||
Nephrotic syndrome can be classified into primary or secondary depending on the underlying etiology. | Nephrotic syndrome can be classified into primary or secondary depending on the underlying etiology.<ref name="pmid19904897">{{cite journal| author=Kodner C| title=Nephrotic syndrome in adults: diagnosis and management. | journal=Am Fam Physician | year= 2009 | volume= 80 | issue= 10 | pages= 1129-34 | pmid=19904897 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19904897 }} </ref> | ||
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Below table lists different typesof nephrotic syndromes: | |||
{| class="wikitable" | {| class="wikitable" | ||
!Different types of nephrotic syndromes | !Different types of nephrotic syndromes | ||
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| rowspan="6" |Podocytopathies | | rowspan="6" |Podocytopathies | ||
| rowspan="2" |Primary | | rowspan="2" |Primary | ||
|Primary minimal change disease | |Primary [[minimal change disease]] | ||
|- | |- | ||
|Primary FSGS | |Primary [[Focal segmental glomerulosclerosis|FSGS]] | ||
|- | |- | ||
| rowspan="4" |Secondary | | rowspan="4" |Secondary | ||
|Infection: HIV | |Infection: [[Human Immunodeficiency Virus (HIV)|HIV]] | ||
|- | |- | ||
|Drugs/toxins: NSAIDs, interferon, | |Drugs/toxins: [[Non-steroidal anti-inflammatory drug|NSAIDs]], [[interferon]], [[pamidronate]], [[lithium]], [[Vaccination|vaccins]], [[envenomation]] | ||
|- | |- | ||
|Malignancies: hodgkin lymphoma, thymoma | |Malignancies: [[Hodgkin's lymphoma|hodgkin lymphoma]], [[thymoma]] | ||
|- | |- | ||
|Genetics: nephrin mutations, podocin | |Genetics: [[nephrin]] mutations, [[podocin]] | ||
|- | |- | ||
| rowspan="2" |Membranous | | rowspan="2" |[[Membranous glomerulonephritis]] | ||
|Primary | |Primary | ||
|Primary membranous nephropathy | |Primary [[membranous nephropathy]] | ||
|- | |- | ||
|Secondary | |Secondary | ||
|Drugs, toxins, malignancies | |Drugs, [[Toxin|toxins]], [[malignancies]] | ||
|- | |- | ||
|Membranoproliferative glomerulonephritis | |[[Membranoproliferative glomerulonephritis]] | ||
|Secondary | |Secondary | ||
| | | | ||
* Autoimmune disorders: SLE, aquired C3 glomerulopathy | * Autoimmune disorders: [[SLE]], aquired C3 glomerulopathy | ||
* Infections: HCV, endocarditis | * Infections: [[Hepatitis C|HCV]], [[endocarditis]] | ||
* Genetics | * [[Genetics]] | ||
* Malignancies | * [[Malignancies]] | ||
* Thrombotic microangiopathy | * [[Thrombotic microangiopathy]] | ||
|- | |- | ||
|Glomerular deposition diseases | |Glomerular deposition diseases | ||
| colspan="2" | | | colspan="2" | | ||
* Diabetes mellitus | * [[Diabetes mellitus]] | ||
* Amyloidosis | * [[Amyloidosis]] | ||
* Monoclonal deposition disease | * [[Monoclonal antibodies|Monoclonal]] deposition disease | ||
* Nodular glomeruloneohritis associated with heavy smoking | * Nodular glomeruloneohritis associated with heavy smoking | ||
|- | |- | ||
|Other lesions | |Other lesions | ||
| colspan="2" | | | colspan="2" | | ||
* Alport syndrome | * [[Alport syndrome]] | ||
* Fabry disease | * [[Fabry's disease|Fabry disease]] | ||
* Nail-patella syndrome | * [[Nail-patella syndrome]] | ||
* | * [[Lipodystrophy|Partial lipodystrophy]] | ||
* | * [[Pre-eclampsia|Preeclampsia]] | ||
|} | |} | ||
*Hereditary Nephropathies: are group of disorders that present with both the features of nephrotic and nephritic syndromes. When features of nephritic syndrome are associated with sensorineural deafness, it is called Alport’s syndrome. Other hereditary nephropathies include IgA Nephropathy, C1q Nephropathy, etc. | *Hereditary Nephropathies: are group of disorders that present with both the features of nephrotic and nephritic syndromes. When features of nephritic syndrome are associated with sensorineural deafness, it is called Alport’s syndrome. Other hereditary nephropathies include IgA Nephropathy, C1q Nephropathy, etc. | ||
Revision as of 19:56, 15 May 2018
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Nephrotic Syndrome Microchapters |
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Diagnosis |
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Case Studies |
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Nephrotic syndrome classification On the Web |
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American Roentgen Ray Society Images of Nephrotic syndrome classification |
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Risk calculators and risk factors for Nephrotic syndrome classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ali Poyan Mehr, M.D. [2]; Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3] Yazan Daaboul,
Overview
Nephrotic syndrome can be classified into primary or secondary depending on the underlying etiology. Primary (idiopathic) nephrotic syndrome is defined as nephrotic syndrome due to a primary glomerular disease. Secondary nephrotic syndrome is defined as nephrotic syndrome due to a primary etiology other than glomerular disorders, such as infections, malignancies, systemic conditions, and medications.
Classification
Etiologic Classification
Nephrotic syndrome can be classified into primary or secondary depending on the underlying etiology.[1]
| Nephrotic syndrome | |||||||||||||||||||
| Primary | Secondary | ||||||||||||||||||
Below table lists different typesof nephrotic syndromes:
| Different types of nephrotic syndromes | Disease name | |
|---|---|---|
| Podocytopathies | Primary | Primary minimal change disease |
| Primary FSGS | ||
| Secondary | Infection: HIV | |
| Drugs/toxins: NSAIDs, interferon, pamidronate, lithium, vaccins, envenomation | ||
| Malignancies: hodgkin lymphoma, thymoma | ||
| Genetics: nephrin mutations, podocin | ||
| Membranous glomerulonephritis | Primary | Primary membranous nephropathy |
| Secondary | Drugs, toxins, malignancies | |
| Membranoproliferative glomerulonephritis | Secondary |
|
| Glomerular deposition diseases |
| |
| Other lesions | ||
- Hereditary Nephropathies: are group of disorders that present with both the features of nephrotic and nephritic syndromes. When features of nephritic syndrome are associated with sensorineural deafness, it is called Alport’s syndrome. Other hereditary nephropathies include IgA Nephropathy, C1q Nephropathy, etc.
References
- ↑ Kodner C (2009). "Nephrotic syndrome in adults: diagnosis and management". Am Fam Physician. 80 (10): 1129–34. PMID 19904897.