IgA nephropathy laboratory findings: Difference between revisions
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*Assess all patients with biopsy-proven IgA nephropathy for secondary causes to rule out common causes of secondary IgA nephropathy | *Assess all patients with biopsy-proven IgA nephropathy for secondary causes to rule out common causes of secondary IgA nephropathy | ||
**Viral serologies: | **Viral serologies: | ||
***HIV | ***[[Human Immunodeficiency Virus (HIV)|HIV]] | ||
***HBV | ***[[HBV]] | ||
***HCV | ***[[HCV]] | ||
**Liver function tests | **[[Liver function tests]] | ||
**Electrophoresis of serum immunoglobulins | **[[Electrophoresis]] of [[serum]] [[Antibody|immunoglobulins]] | ||
* Assess the risk of progression and prognosis by the following parameters at diagnosis and at follow-up: | * Assess the risk of progression and prognosis by the following parameters at diagnosis and at follow-up: | ||
**Blood pressure measurement | **[[Blood pressure]] measurement | ||
**Serum creatinine to estimate glomerular filtration rate (GFR) | **[[Creatinine|Serum creatinine]] to estimate [[Glomerular filtration rate|glomerular filtration rate (GFR)]] | ||
**Proteinuria | **[[Proteinuria]] | ||
**Pathological features | **Pathological features | ||
*A kidney biopsy is to be considered only if signs of | *A kidney biopsy is to be considered only if signs of [[acute kidney injury]] and [[macroscopic]] [[hematuria]] persist for at least 5 days since the onset of kidney injury. | ||
==References== | ==References== | ||
Revision as of 16:47, 21 May 2018
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IgA nephropathy Microchapters |
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IgA nephropathy laboratory findings On the Web |
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Risk calculators and risk factors for IgA nephropathy laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
- There are no specific and sensitive diagnostic laboratory findings associated with IgA nephropathy.
Laboratory Findings
- There are no specific and sensitive diagnostic laboratory findings associated with IgA nephropathy.
- Some patients with IgA nephropathy may have elevated concentration of serum total IgA.
- The urinary Immunoglobulins are not distinctive in IgA nephropathy.
Initial Evaluation
- Assess all patients with biopsy-proven IgA nephropathy for secondary causes to rule out common causes of secondary IgA nephropathy
- Viral serologies:
- Liver function tests
- Electrophoresis of serum immunoglobulins
- Assess the risk of progression and prognosis by the following parameters at diagnosis and at follow-up:
- Blood pressure measurement
- Serum creatinine to estimate glomerular filtration rate (GFR)
- Proteinuria
- Pathological features
- A kidney biopsy is to be considered only if signs of acute kidney injury and macroscopic hematuria persist for at least 5 days since the onset of kidney injury.