Myeloproliferative neoplasm causes: Difference between revisions
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Polycythemia vera | Polycythemia vera | ||
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*''JAK2'' ''V617F'' | *''JAK2'' ''V617F'' in 95% of cases | ||
*''CALR'' | *''CALR'' | ||
*''MPL'' | *''MPL'' | ||
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Essential thrombocythemia | Essential thrombocythemia | ||
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*''JAK2'' ''V617F'' | *''JAK2'' ''V617F'' in 50-60% of cases | ||
*''CALR'' | *''CALR'' | ||
*''MPL'' | *''MPL'' | ||
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Primary myelofibrosis | Primary myelofibrosis | ||
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*''JAK2'' ''V617F'' | *''JAK2'' ''V617F'' in 50-60% of cases | ||
*''CALR'' | *''CALR'' | ||
*''MPL'' | *''MPL'' |
Revision as of 17:53, 10 June 2018
Myeloproliferative Neoplasm Microchapters |
Differentiating myeloproliferative neoplasm from other Diseases |
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Diagnosis |
Treatment |
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Myeloproliferative neoplasm causes On the Web |
American Roentgen Ray Society Images of Myeloproliferative neoplasm causes |
Directions to Hospitals Treating Myeloproliferative neoplasm |
Risk calculators and risk factors for Myeloproliferative neoplasm causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3]
Overview
Myeloproliferative neoplasm is caused by mutations in various genes. Different gene mutations are responsible for each of the 8 subtypes of myeloproliferative neoplasms. [1][2][1]
Causes
Myeloproliferative neoplasm subtype | Causative gene mutation |
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Polycythemia vera |
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Essential thrombocythemia |
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Primary myelofibrosis |
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Chronic myeloid leukemia |
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Chronic neutrophilic leukemia |
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Chronic eosinophilic leukemia |
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Myeloproliferative neoplasm, unclassifiable |
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Mastocytosis |
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References
- ↑ 1.0 1.1 Ganfyd. Polycythaemia vera 2015.http://www.ganfyd.org/index.php?title=Polycythemia_vera
- ↑ Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID http://dx.doi.org/10.1182/blood-2013-11-538983 Check
|pmid=
value (help).