Narrative Review: Acute Kidney Injury

Narrative Review
Narrative Review: Death
Narrative Review: Stroke
Narrative Review: Myocardial Infarction
Narrative Review: Acute Kidney Injury
Narrative Review: Bleeding

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]

Site	Patient	AE	Complication	Event date	AE code
xxx	xxx	x		MM/DD/YYYY	xxx

 Renal Dysfunction

Symptoms:

O Anuria

O Oliguria

O Flank pain

O Hematuria

Laboratory:

Date	Time	BUN/Cr	Na/K	Urine output	Arterial pH	HCO3	HgB
MM/DD/YYYY	xx:xx
MM/DD/YYYY	xx:xx
MM/DD/YYYY	xx:xx

Stage criteria for AKI based on Serum Creatinine

O Stage 1: 1.5–1.9 times baseline OR ≥0.3 mg/dl (≥26.5 μmol/l) increase

O Stage 2: 2.0–2.9 times baseline

O Stage 3: 3.0 times baseline OR Increase in serum creatinine to ≥4.0 mg/dl (≥353.6 μmol/l) OR Initiation of renal replacement therapy

Renal dysfunction Definition

Persistent decrease in eGFR of > 20 ml/min/1.73 m2 from baseline >48 hours that does not respond to simple measures such as decreasing diuresis or volume replacement). [Note: eGFR via CKD-Epi equation]

Acute Kidney Injury (AKI) definition

AKI is defined as any of the following (Not Graded):

O Increase in SCr by X0.3 mg/dl (≥26.5 μmol/l) within 48 hours; or

O Increase in SCr to ≥1.5 times baseline, which is known or presumed to have occurred within the prior 7 days; or

O Urine volume <0.5 ml/kg/h for 6 hours.

 Event(s)

Event (1):

• Site Reported Event Onset Date: MM/DD/YYYY

• Event summary:
  • Symptoms and sign:
    • Subject presented with [sign and symptom] on MM/DD/YYYY.
    • Important characteristics of the chief complaint such as severity, site, and duration.
    • Other important symptoms related to the chief complaint.

• • Past Medical History: [eg. CAD, Severe mitral stenosis, former tobacco use, dyslipidemia, ...]
  • Past Surgical History: [including date]
  • Medications: [relevant to the event not all]
  • Physical assessment:
    • Vital signs
    • Positive physical examinations or related negative examinations.

Event (2):

• Site Reported Event Onset Date: MM/DD/YYYY
• Event summary:
  • Symptoms and sign:
    • Subject presented with [sign and symptom] on MM/DD/YYYY.
    • Important characteristics of the chief complaint such as severity, site, and duration.
    • Other important symptoms related to the chief complaint.

• • Past Medical History: [eg. CAD, Severe mitral stenosis, former tobacco use, dyslipidemia, ...]
  • Past Surgical History: [including date]
  • Medications: [relevant to the event not all]
  • Physical assessment:
    • Vital signs
    • Positive physical examinations or related negative examinations.

Procedure

• Index Procedure Date/Time:
  • mm/dd/YYYY at xx:xx [insert date and time]
• Index Procedure Detail:
  • On mm/dd/YYYY at xx:xx [insert date and time] the subject underwent a [select surgical correction] for [select etiology].
  • Access site details
  • The site reported that there were/were not procedural complication(s). 

Other Laboratory data and Imaging

• Other laboratory:
  • Date/ name/ value

• ECG / date:

• ECHO / date:
• CXR / date:
• Other imaging and diagnostic tests / date:

Consults

• Date and time of consult
• Suggested treatments

Clinical course

• Date and time of events:
• Dialysis / time
• Patient condition got worse or better.

Treatment and outcome

• List of relevant medical treatments
• Outcome [Discharge / Hospice / Death]