Pseudotumor cerebri differential diagnosis: Difference between revisions

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==Overview==
==Overview==
[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
==Differentiating [Disease name] from other Diseases==
Pseudotumor cerebri must be differentiated from other diseases that cause increased intracranial pressure:


OR
=== Secondary intracranial hypertension ===
* Intracranial mass lesions (tumor, abscess)


[Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].
* Obstruction of venous outflow, eg, venous sinus thrombosis, jugular vein compression, neck surgery


==Differentiating [Disease name] from other Diseases==
* Obstructive hydrocephalus
[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].


OR
* Decreased CSF absorption, eg, arachnoid granulation adhesions after bacterial or other infectious
* meningitis, subarachnoid hemorrhage
* Increased cerebrospinal fluid (CSF) production, eg, choroid plexus papilloma
* Malignant systemic hypertension
Most of these condition can be ruled out by imaging techniques like MRI, CT scan and MR venography.(83-85 uptodate clinical and diagnosis)


[Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].
=== Bilateral disc abnormalities ===
* Pseudopapilledema: Some non-diseased conditions like congenital disc abnormalities ( drusen and myelinated nerve fibers), farsightedness and hyperopia can cause the appearance of papilledema(29-30 upto ddx papill)


OR
* Malignant hypertention: Severe systemic hypertension can mimic papilledema but it also cause other signs like hemorrhages, exudates, cotton wool spots, diplopia, scotomata and photopsia which help us differentiate it from other causes of papilledema.(32-33-34 upto ddx papilledema)


As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
* Diabetic papillopathy: Diabetic papillopathy can mimic papilledema from increased instracranial pressure with telangiectasias, hemorrhages and macular star.(35 upto ddx papilledema)


===Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]===
* Hyperviscosity, hypotension, and blood loss (39 uptodate ddx papilledema)
* Toxic optic neuropathies: methanol, ethambutol and ethylene glycol can cause papilledema early in their course.(9 uptodate ddx papilledema)


On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].
== Refrences ==
{|
{|
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|Diseases
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Clinical manifestations'''
| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Para-clinical findings
! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings
| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Gold standard'''
| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|Additional findings
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
|-
|-
| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Symptoms'''
| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Symptoms'''
! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical examination
! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical examination
|-
|-
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab Findings
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Histopathology
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
|-  
|-  
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 1
! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 2
! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 1
! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 2
! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 1
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 2
! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 3
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 3
|-
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 1
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 1

Revision as of 16:53, 27 July 2018

Pseudotumor cerebri Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Differentiating [Disease name] from other Diseases

Pseudotumor cerebri must be differentiated from other diseases that cause increased intracranial pressure:

Secondary intracranial hypertension

  • Intracranial mass lesions (tumor, abscess)
  • Obstruction of venous outflow, eg, venous sinus thrombosis, jugular vein compression, neck surgery
  • Obstructive hydrocephalus
  • Decreased CSF absorption, eg, arachnoid granulation adhesions after bacterial or other infectious
  • meningitis, subarachnoid hemorrhage
  • Increased cerebrospinal fluid (CSF) production, eg, choroid plexus papilloma
  • Malignant systemic hypertension

Most of these condition can be ruled out by imaging techniques like MRI, CT scan and MR venography.(83-85 uptodate clinical and diagnosis)

Bilateral disc abnormalities

  • Pseudopapilledema: Some non-diseased conditions like congenital disc abnormalities ( drusen and myelinated nerve fibers), farsightedness and hyperopia can cause the appearance of papilledema(29-30 upto ddx papill)
  • Malignant hypertention: Severe systemic hypertension can mimic papilledema but it also cause other signs like hemorrhages, exudates, cotton wool spots, diplopia, scotomata and photopsia which help us differentiate it from other causes of papilledema.(32-33-34 upto ddx papilledema)
  • Diabetic papillopathy: Diabetic papillopathy can mimic papilledema from increased instracranial pressure with telangiectasias, hemorrhages and macular star.(35 upto ddx papilledema)
  • Hyperviscosity, hypotension, and blood loss (39 uptodate ddx papilledema)
  • Toxic optic neuropathies: methanol, ethambutol and ethylene glycol can cause papilledema early in their course.(9 uptodate ddx papilledema)

Refrences

Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical examination
Lab Findings Imaging Histopathology
Symptom 1 Symptom 2 Symptom 3 Physical exam 1 Physical exam 2 Physical exam 3 Lab 1 Lab 2 Lab 3 Imaging 1 Imaging 2 Imaging 3
Differential Diagnosis 1
Differential Diagnosis 2
Differential Diagnosis 3
Diseases Symptom 1 Symptom 2 Symptom 3 Physical exam 1 Physical exam 2 Physical exam 3 Lab 1 Lab 2 Lab 3 Imaging 1 Imaging 2 Imaging 3 Histopathology Gold standard Additional findings
Differential Diagnosis 4
Differential Diagnosis 5
Differential Diagnosis 6

References

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