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! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
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! rowspan="22" style="background: #DCDCDC; padding: 5px; text-align: center;" |Prerenal causes
! rowspan="24" style="background: #DCDCDC; padding: 5px; text-align: center;" |Prerenal causes
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Alcohol poisoning]]<ref name="pmid15589492">{{cite journal |vauthors=Pletcher MJ, Maselli J, Gonzales R |title=Uncomplicated alcohol intoxication in the emergency department: an analysis of the National Hospital Ambulatory Medical Care Survey |journal=Am. J. Med. |volume=117 |issue=11 |pages=863–7 |date=December 2004 |pmid=15589492 |doi=10.1016/j.amjmed.2004.07.042 |url=}}</ref><ref name="pmid2927129">{{cite journal |vauthors=Cherpitel CJ |title=Breath analysis and self-reports as measures of alcohol-related emergency room admissions |journal=J. Stud. Alcohol |volume=50 |issue=2 |pages=155–61 |date=March 1989 |pmid=2927129 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Alcohol poisoning]]
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Thiamine]] must be given to prevent [[Wernicke's encephalopathy]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Thiamine]] must be given to prevent [[Wernicke's encephalopathy]]
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Aspergillosis|'''Aspergillosis''']]<ref name="pmid11880955">{{cite journal |vauthors=Marr KA, Carter RA, Crippa F, Wald A, Corey L |title=Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients |journal=Clin. Infect. Dis. |volume=34 |issue=7 |pages=909–17 |date=April 2002 |pmid=11880955 |doi=10.1086/339202 |url=}}</ref><ref name="pmid16886149">{{cite journal |vauthors=Cornillet A, Camus C, Nimubona S, Gandemer V, Tattevin P, Belleguic C, Chevrier S, Meunier C, Lebert C, Aupée M, Caulet-Maugendre S, Faucheux M, Lelong B, Leray E, Guiguen C, Gangneux JP |title=Comparison of epidemiological, clinical, and biological features of invasive aspergillosis in neutropenic and nonneutropenic patients: a 6-year survey |journal=Clin. Infect. Dis. |volume=43 |issue=5 |pages=577–84 |date=September 2006 |pmid=16886149 |doi=10.1086/505870 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Aspergillosis|'''Aspergillosis''']]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Polymerase chain reaction|Polymerase chain reaction (PCR)]]  
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Polymerase chain reaction|Polymerase chain reaction (PCR)]]  
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cholera|'''Cholera''']]<ref name="pmid19842974">{{cite journal |vauthors=Weil AA, Khan AI, Chowdhury F, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F, Harris JB |title=Clinical outcomes in household contacts of patients with cholera in Bangladesh |journal=Clin. Infect. Dis. |volume=49 |issue=10 |pages=1473–9 |date=November 2009 |pmid=19842974 |pmc=2783773 |doi=10.1086/644779 |url=}}</ref><ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref><ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref><ref name="pmid21696312">{{cite journal |vauthors=Harris JB, Ivers LC, Ferraro MJ |title=Case records of the Massachusetts General Hospital. Case 19-2011. A 4-year-old Haitian boy with vomiting and diarrhea |journal=N. Engl. J. Med. |volume=364 |issue=25 |pages=2452–61 |date=June 2011 |pmid=21696312 |doi=10.1056/NEJMcpc1100927 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cholera|'''Cholera''']]<ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Congestive heart failure]] (CHF)<ref name="pmid17724259">{{cite journal |vauthors=Solomon SD, Dobson J, Pocock S, Skali H, McMurray JJ, Granger CB, Yusuf S, Swedberg K, Young JB, Michelson EL, Pfeffer MA |title=Influence of nonfatal hospitalization for heart failure on subsequent mortality in patients with chronic heart failure |journal=Circulation |volume=116 |issue=13 |pages=1482–7 |date=September 2007 |pmid=17724259 |doi=10.1161/CIRCULATIONAHA.107.696906 |url=}}</ref><ref name="pmid15687312">{{cite journal |vauthors=Fonarow GC, Adams KF, Abraham WT, Yancy CW, Boscardin WJ |title=Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis |journal=JAMA |volume=293 |issue=5 |pages=572–80 |date=February 2005 |pmid=15687312 |doi=10.1001/jama.293.5.572 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Congestive heart failure]] (CHF)
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Dehydration]]<ref name="pmid15187057">{{cite journal |vauthors=Steiner MJ, DeWalt DA, Byerley JS |title=Is this child dehydrated? |journal=JAMA |volume=291 |issue=22 |pages=2746–54 |date=June 2004 |pmid=15187057 |doi=10.1001/jama.291.22.2746 |url=}}</ref><ref name="pmid9220501">{{cite journal |vauthors=Vega RM, Avner JR |title=A prospective study of the usefulness of clinical and laboratory parameters for predicting percentage of dehydration in children |journal=Pediatr Emerg Care |volume=13 |issue=3 |pages=179–82 |date=June 1997 |pmid=9220501 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Dehydration]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Diarrhea]] and/or [[vomiting]]<ref name="pmid2178747">{{cite journal |vauthors=Carpenter DO |title=Neural mechanisms of emesis |journal=Can. J. Physiol. Pharmacol. |volume=68 |issue=2 |pages=230–6 |date=February 1990 |pmid=2178747 |doi= |url=}}</ref><ref name="pmid22454468">{{cite journal |vauthors=Bresee JS, Marcus R, Venezia RA, Keene WE, Morse D, Thanassi M, Brunett P, Bulens S, Beard RS, Dauphin LA, Slutsker L, Bopp C, Eberhard M, Hall A, Vinje J, Monroe SS, Glass RI |title=The etiology of severe acute gastroenteritis among adults visiting emergency departments in the United States |journal=J. Infect. Dis. |volume=205 |issue=9 |pages=1374–81 |date=May 2012 |pmid=22454468 |doi=10.1093/infdis/jis206 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Diarrhea]] and/or [[vomiting]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drugs]]/[[Toxin|toxins]]<ref name="pmid1883120">{{cite journal |vauthors=Toto RD, Mitchell HC, Lee HC, Milam C, Pettinger WA |title=Reversible renal insufficiency due to angiotensin converting enzyme inhibitors in hypertensive nephrosclerosis |journal=Ann. Intern. Med. |volume=115 |issue=7 |pages=513–9 |date=October 1991 |pmid=1883120 |doi= |url=}}</ref><ref name="pmid4715199">{{cite journal |vauthors=Bismuth C, Gaultier M, Conso F, Efthymiou ML |title=Hyperkalemia in acute digitalis poisoning: prognostic significance and therapeutic implications |journal=Clin. Toxicol. |volume=6 |issue=2 |pages=153–62 |date=1973 |pmid=4715199 |doi=10.3109/15563657308990513 |url=}}</ref>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drugs]]/[[Toxin|toxins]]


| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Esophageal varices|'''Esophageal varices bleeding''']]<ref name="pmid6970703">{{cite journal |vauthors=Graham DY, Smith JL |title=The course of patients after variceal hemorrhage |journal=Gastroenterology |volume=80 |issue=4 |pages=800–9 |date=April 1981 |pmid=6970703 |doi= |url=}}</ref><ref name="pmid20638742">{{cite journal |vauthors=de Franchis R |title=Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension |journal=J. Hepatol. |volume=53 |issue=4 |pages=762–8 |date=October 2010 |pmid=20638742 |doi=10.1016/j.jhep.2010.06.004 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Esophageal varices|'''Esophageal varices bleeding''']]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Heart disease]]<ref name="pmid2030718">{{cite journal |vauthors=LaCroix AZ, Lang J, Scherr P, Wallace RB, Cornoni-Huntley J, Berkman L, Curb JD, Evans D, Hennekens CH |title=Smoking and mortality among older men and women in three communities |journal=N. Engl. J. Med. |volume=324 |issue=23 |pages=1619–25 |date=June 1991 |pmid=2030718 |doi=10.1056/NEJM199106063242303 |url=}}</ref><ref name="pmid19581259">{{cite journal |vauthors=Mahle WT, Newburger JW, Matherne GP, Smith FC, Hoke TR, Koppel R, Gidding SS, Beekman RH, Grosse SD |title=Role of pulse oximetry in examining newborns for congenital heart disease: a scientific statement from the AHA and AAP |journal=Pediatrics |volume=124 |issue=2 |pages=823–36 |date=August 2009 |pmid=19581259 |doi=10.1542/peds.2009-1397 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Heart disease]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemorrhage]]<ref name="pmid21098468">{{cite journal |vauthors=Achneck HE, Sileshi B, Parikh A, Milano CA, Welsby IJ, Lawson JH |title=Pathophysiology of bleeding and clotting in the cardiac surgery patient: from vascular endothelium to circulatory assist device surface |journal=Circulation |volume=122 |issue=20 |pages=2068–77 |date=November 2010 |pmid=21098468 |doi=10.1161/CIRCULATIONAHA.110.936773 |url=}}</ref><ref name="pmid3487361">{{cite journal |vauthors=Gralnick HR, Rick ME, McKeown LP, Williams SB, Parker RI, Maisonneuve P, Jenneau C, Sultan Y |title=Platelet von Willebrand factor: an important determinant of the bleeding time in type I von Willebrand's disease |journal=Blood |volume=68 |issue=1 |pages=58–61 |date=July 1986 |pmid=3487361 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemorrhage]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemolysis]]<ref name="pmid3814817">{{cite journal |vauthors=Liesveld JL, Rowe JM, Lichtman MA |title=Variability of the erythropoietic response in autoimmune hemolytic anemia: analysis of 109 cases |journal=Blood |volume=69 |issue=3 |pages=820–6 |date=March 1987 |pmid=3814817 |doi= |url=}}</ref><ref name="pmid7365971">{{cite journal |vauthors=Marchand A, Galen RS, Van Lente F |title=The predictive value of serum haptoglobin in hemolytic disease |journal=JAMA |volume=243 |issue=19 |pages=1909–11 |date=May 1980 |pmid=7365971 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemolysis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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! align="center" style="background:#4479BA; color: #FFFFFF;" |Comments
! align="center" style="background:#4479BA; color: #FFFFFF;" |Comments
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hepatorenal syndrome]]<ref name="pmid19776409">{{cite journal |vauthors=Ginès P, Schrier RW |title=Renal failure in cirrhosis |journal=N. Engl. J. Med. |volume=361 |issue=13 |pages=1279–90 |date=September 2009 |pmid=19776409 |doi=10.1056/NEJMra0809139 |url=}}</ref><ref name="pmid8550036">{{cite journal |vauthors=Arroyo V, Ginès P, Gerbes AL, Dudley FJ, Gentilini P, Laffi G, Reynolds TB, Ring-Larsen H, Schölmerich J |title=Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club |journal=Hepatology |volume=23 |issue=1 |pages=164–76 |date=January 1996 |pmid=8550036 |doi=10.1002/hep.510230122 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hepatorenal syndrome]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cardiomyopathy|Ischemic cardiomyopathy]]<ref name="pmid16567565">{{cite journal |vauthors=Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, Moss AJ, Seidman CE, Young JB |title=Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention |journal=Circulation |volume=113 |issue=14 |pages=1807–16 |date=April 2006 |pmid=16567565 |doi=10.1161/CIRCULATIONAHA.106.174287 |url=}}</ref><ref name="pmid15689345">{{cite journal |vauthors=Corrado D, Pelliccia A, Bjørnstad HH, Vanhees L, Biffi A, Borjesson M, Panhuyzen-Goedkoop N, Deligiannis A, Solberg E, Dugmore D, Mellwig KP, Assanelli D, Delise P, van-Buuren F, Anastasakis A, Heidbuchel H, Hoffmann E, Fagard R, Priori SG, Basso C, Arbustini E, Blomstrom-Lundqvist C, McKenna WJ, Thiene G |title=Cardiovascular pre-participation screening of young competitive athletes for prevention of sudden death: proposal for a common European protocol. Consensus Statement of the Study Group of Sport Cardiology of the Working Group of Cardiac Rehabilitation and Exercise Physiology and the Working Group of Myocardial and Pericardial Diseases of the European Society of Cardiology |journal=Eur. Heart J. |volume=26 |issue=5 |pages=516–24 |date=March 2005 |pmid=15689345 |doi=10.1093/eurheartj/ehi108 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cardiomyopathy|Ischemic cardiomyopathy]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Liver cirrhosis]]<ref name="pmid24076364">{{cite journal |vauthors=Ge PS, Runyon BA |title=The changing role of beta-blocker therapy in patients with cirrhosis |journal=J. Hepatol. |volume=60 |issue=3 |pages=643–53 |date=March 2014 |pmid=24076364 |doi=10.1016/j.jhep.2013.09.016 |url=}}</ref><ref name="pmid3533689">{{cite journal |vauthors=Becker CD, Scheidegger J, Marincek B |title=Hepatic vein occlusion: morphologic features on computed tomography and ultrasonography |journal=Gastrointest Radiol |volume=11 |issue=4 |pages=305–11 |date=1986 |pmid=3533689 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Liver cirrhosis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |Irreversible and a transplant is usually needed
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Irreversible and a transplant is usually needed
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Malignant hypertension]]<ref name="pmid23102030">{{cite journal |vauthors=Johnson W, Nguyen ML, Patel R |title=Hypertension crisis in the emergency department |journal=Cardiol Clin |volume=30 |issue=4 |pages=533–43 |date=November 2012 |pmid=23102030 |doi=10.1016/j.ccl.2012.07.011 |url=}}</ref><ref name="pmid16627047">{{cite journal |vauthors=Elliott WJ |title=Clinical features in the management of selected hypertensive emergencies |journal=Prog Cardiovasc Dis |volume=48 |issue=5 |pages=316–25 |date=2006 |pmid=16627047 |doi=10.1016/j.pcad.2006.02.004 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Malignant hypertension]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Myocarditis]]<ref name="pmid39746742">{{cite journal |vauthors=Dec GW, Palacios IF, Fallon JT, Aretz HT, Mills J, Lee DC, Johnson RA |title=Active myocarditis in the spectrum of acute dilated cardiomyopathies. Clinical features, histologic correlates, and clinical outcome |journal=N. Engl. J. Med. |volume=312 |issue=14 |pages=885–90 |date=April 1985 |pmid=3974674 |doi=10.1056/NEJM198504043121404 |url=}}</ref>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Myocarditis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |Not applicable
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Not applicable
|-
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Peritonitis]]<ref name="pmid97980132">{{cite journal |vauthors=Such J, Runyon BA |title=Spontaneous bacterial peritonitis |journal=Clin. Infect. Dis. |volume=27 |issue=4 |pages=669–74; quiz 675–6 |date=October 1998 |pmid=9798013 |doi= |url=}}</ref><ref name="pmid22106722">{{cite journal |vauthors=Runyon BA |title=Monomicrobial nonneutrocytic bacterascites: a variant of spontaneous bacterial peritonitis |journal=Hepatology |volume=12 |issue=4 Pt 1 |pages=710–5 |date=October 1990 |pmid=2210672 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Peritonitis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Polycythemia]]<ref name="pmid90251652">{{cite journal |vauthors=Gregg XT, Prchal JT |title=Erythropoietin receptor mutations and human disease |journal=Semin. Hematol. |volume=34 |issue=1 |pages=70–6 |date=January 1997 |pmid=9025165 |doi= |url=}}</ref><ref name="pmid92925432">{{cite journal |vauthors=Kralovics R, Indrak K, Stopka T, Berman BW, Prchal JF, Prchal JT |title=Two new EPO receptor mutations: truncated EPO receptors are most frequently associated with primary familial and congenital polycythemias |journal=Blood |volume=90 |issue=5 |pages=2057–61 |date=September 1997 |pmid=9292543 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Polycythemia]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Phlebotomy]] is the usual treatment
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Phlebotomy]] is the usual treatment
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Respiratory distress syndrome]]<ref name="pmid265428772">{{cite journal |vauthors=Hooper SB, Te Pas AB, Kitchen MJ |title=Respiratory transition in the newborn: a three-phase process |journal=Arch. Dis. Child. Fetal Neonatal Ed. |volume=101 |issue=3 |pages=F266–71 |date=May 2016 |pmid=26542877 |doi=10.1136/archdischild-2013-305704 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Respiratory distress syndrome]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Shock]]<ref name="pmid24171518">{{cite journal |vauthors=Vincent JL, De Backer D |title=Circulatory shock |journal=N. Engl. J. Med. |volume=369 |issue=18 |pages=1726–34 |date=October 2013 |pmid=24171518 |doi=10.1056/NEJMra1208943 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Shock]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Toxic megacolon]]<ref name="pmid5305933">{{cite journal |vauthors=Jalan KN, Sircus W, Card WI, Falconer CW, Bruce CB, Crean GP, McManus JP, Small WP, Smith AN |title=An experience of ulcerative colitis. I. Toxic dilation in 55 cases |journal=Gastroenterology |volume=57 |issue=1 |pages=68–82 |date=July 1969 |pmid=5305933 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Toxic megacolon]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
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! align="center" style="background:#4479BA; color: #FFFFFF;" |Comments
! align="center" style="background:#4479BA; color: #FFFFFF;" |Comments
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! rowspan="10" style="background: #DCDCDC; padding: 5px; text-align: center;" |Renal causes
! rowspan="11" style="background: #DCDCDC; padding: 5px; text-align: center;" |Renal causes
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Acute interstitial nephritis]]<ref name="pmid11020015">{{cite journal |vauthors=Schwarz A, Krause PH, Kunzendorf U, Keller F, Distler A |title=The outcome of acute interstitial nephritis: risk factors for the transition from acute to chronic interstitial nephritis |journal=Clin. Nephrol. |volume=54 |issue=3 |pages=179–90 |date=September 2000 |pmid=11020015 |doi= |url=}}</ref><ref name="pmid20336051">{{cite journal |vauthors=Praga M, González E |title=Acute interstitial nephritis |journal=Kidney Int. |volume=77 |issue=11 |pages=956–61 |date=June 2010 |pmid=20336051 |doi=10.1038/ki.2010.89 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Acute interstitial nephritis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |History of long term [[analgesic]] use  
| style="background: #F5F5F5; padding: 5px; text-align: center;" |History of long term [[analgesic]] use  
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Acute tubular necrosis]]<ref name="pmid22890468">{{cite journal |vauthors=Khwaja A |title=KDIGO clinical practice guidelines for acute kidney injury |journal=Nephron Clin Pract |volume=120 |issue=4 |pages=c179–84 |date=2012 |pmid=22890468 |doi=10.1159/000339789 |url=}}</ref><ref name="pmid15680458">{{cite journal |vauthors=Lameire N, Van Biesen W, Vanholder R |title=Acute renal failure |journal=Lancet |volume=365 |issue=9457 |pages=417–30 |date=2005 |pmid=15680458 |doi=10.1016/S0140-6736(05)17831-3 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Acute tubular necrosis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Furosemide]] stress testing for staging
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Furosemide]] stress testing for staging
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cancer]]<ref name="pmid16360438">{{cite journal |vauthors=Gudbjartsson T, Thoroddsen A, Petursdottir V, Hardarson S, Magnusson J, Einarsson GV |title=Effect of incidental detection for survival of patients with renal cell carcinoma: results of population-based study of 701 patients |journal=Urology |volume=66 |issue=6 |pages=1186–91 |date=December 2005 |pmid=16360438 |doi=10.1016/j.urology.2005.07.009 |url=}}</ref><ref name="pmid5125665">{{cite journal |vauthors=Skinner DG, Colvin RB, Vermillion CD, Pfister RC, Leadbetter WF |title=Diagnosis and management of renal cell carcinoma. A clinical and pathologic study of 309 cases |journal=Cancer |volume=28 |issue=5 |pages=1165–77 |date=November 1971 |pmid=5125665 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cancer]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Renal cell carcinoma]] types: [[Clear cell]] (75%), Chromophilic (15%), [[Chromophobic]] (5%), [[Oncocytoma]] (3%), [[Collecting duct]] (2%)
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Renal cell carcinoma]] types: [[Clear cell]] (75%), Chromophilic (15%), [[Chromophobic]] (5%), [[Oncocytoma]] (3%), [[Collecting duct]] (2%)
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Congenital disease|'''Congenital kidney disease''']]<ref name="pmid12197558">{{cite journal |vauthors=Queisser-Luft A, Stolz G, Wiesel A, Schlaefer K, Spranger J |title=Malformations in newborn: results based on 30,940 infants and fetuses from the Mainz congenital birth defect monitoring system (1990-1998) |journal=Arch. Gynecol. Obstet. |volume=266 |issue=3 |pages=163–7 |date=July 2002 |pmid=12197558 |doi= |url=}}</ref><ref name="pmid19536081">{{cite journal |vauthors=Sanna-Cherchi S, Ravani P, Corbani V, Parodi S, Haupt R, Piaggio G, Innocenti ML, Somenzi D, Trivelli A, Caridi G, Izzi C, Scolari F, Mattioli G, Allegri L, Ghiggeri GM |title=Renal outcome in patients with congenital anomalies of the kidney and urinary tract |journal=Kidney Int. |volume=76 |issue=5 |pages=528–33 |date=September 2009 |pmid=19536081 |doi=10.1038/ki.2009.220 |url=}}</ref><ref name="pmid11992035">{{cite journal |vauthors=Glassberg KI |title=Normal and abnormal development of the kidney: a clinician's interpretation of current knowledge |journal=J. Urol. |volume=167 |issue=6 |pages=2339–50; discussion 2350–1 |date=June 2002 |pmid=11992035 |doi= |url=}}</ref>
| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Congenital disease|'''Congenital kidney disease''']]
- [[Agenesis]]
- [[Agenesis]]


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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[End stage renal disease]]<ref name="pmid20054047">{{cite journal |vauthors=Abboud H, Henrich WL |title=Clinical practice. Stage IV chronic kidney disease |journal=N. Engl. J. Med. |volume=362 |issue=1 |pages=56–65 |date=January 2010 |pmid=20054047 |doi=10.1056/NEJMcp0906797 |url=}}</ref><ref name="pmid28614683">{{cite journal |vauthors=Denic A, Mathew J, Lerman LO, Lieske JC, Larson JJ, Alexander MP, Poggio E, Glassock RJ, Rule AD |title=Single-Nephron Glomerular Filtration Rate in Healthy Adults |journal=N. Engl. J. Med. |volume=376 |issue=24 |pages=2349–2357 |date=June 2017 |pmid=28614683 |pmc=5664219 |doi=10.1056/NEJMoa1614329 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[End stage renal disease]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Toxin|'''Endogenous toxins''']]<ref name="pmid20533382">{{cite journal |vauthors=Borowitz MJ, Craig FE, Digiuseppe JA, Illingworth AJ, Rosse W, Sutherland DR, Wittwer CT, Richards SJ |title=Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry |journal=Cytometry B Clin Cytom |volume=78 |issue=4 |pages=211–30 |date=July 2010 |pmid=20533382 |doi=10.1002/cyto.b.20525 |url=}}</ref><ref name="pmid6282181">{{cite journal |vauthors=Knochel JP |title=Rhabdomyolysis and myoglobinuria |journal=Annu. Rev. Med. |volume=33 |issue= |pages=435–43 |date=1982 |pmid=6282181 |doi=10.1146/annurev.me.33.020182.002251 |url=}}</ref><ref name="pmid17338959">{{cite journal |vauthors=Giannoglou GD, Chatzizisis YS, Misirli G |title=The syndrome of rhabdomyolysis: Pathophysiology and diagnosis |journal=Eur. J. Intern. Med. |volume=18 |issue=2 |pages=90–100 |date=March 2007 |pmid=17338959 |doi=10.1016/j.ejim.2006.09.020 |url=}}</ref><ref name="pmid6645213">{{cite journal |vauthors=Coe FL |title=Uric acid and calcium oxalate nephrolithiasis |journal=Kidney Int. |volume=24 |issue=3 |pages=392–403 |date=September 1983 |pmid=6645213 |doi= |url=}}</ref><ref name="pmid15202612">{{cite journal |vauthors=Maalouf NM, Cameron MA, Moe OW, Sakhaee K |title=Novel insights into the pathogenesis of uric acid nephrolithiasis |journal=Curr. Opin. Nephrol. Hypertens. |volume=13 |issue=2 |pages=181–9 |date=March 2004 |pmid=15202612 |doi= |url=}}</ref>
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Toxin|'''Endogenous toxins''']]
- [[Hemoglobin]]
- [[Hemoglobin]]


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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Glomerulonephritis]]<ref name="pmid2915517">{{cite journal |vauthors=Ellis EN, Mauer SM, Sutherland DE, Steffes MW |title=Glomerular capillary morphology in normal humans |journal=Lab. Invest. |volume=60 |issue=2 |pages=231–6 |date=February 1989 |pmid=2915517 |doi= |url=}}</ref><ref name="pmid27373970">{{cite journal |vauthors=Dickinson BL |title=Unraveling the immunopathogenesis of glomerular disease |journal=Clin. Immunol. |volume=169 |issue= |pages=89–97 |date=August 2016 |pmid=27373970 |doi=10.1016/j.clim.2016.06.011 |url=}}</ref><ref name="pmid7955787">{{cite journal |vauthors=Trachtman H, Bergwerk A, Gauthier B |title=Isolated proteinuria in children. Natural history and indications for renal biopsy |journal=Clin Pediatr (Phila) |volume=33 |issue=8 |pages=468–72 |date=August 1994 |pmid=7955787 |doi=10.1177/000992289403300804 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Glomerulonephritis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" |Renal [[biopsy]], Light and electron microscopy, Immunofluorescence aid diagnosis
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Renal [[biopsy]], Light and electron microscopy, Immunofluorescence aid diagnosis
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Goodpasture syndrome]]<ref name="pmid12969182">{{cite journal |vauthors=Pusey CD |title=Anti-glomerular basement membrane disease |journal=Kidney Int. |volume=64 |issue=4 |pages=1535–50 |date=October 2003 |pmid=12969182 |doi=10.1046/j.1523-1755.2003.00241.x |url=}}</ref><ref name="pmid8914046">{{cite journal |vauthors=Bolton WK |title=Goodpasture's syndrome |journal=Kidney Int. |volume=50 |issue=5 |pages=1753–66 |date=November 1996 |pmid=8914046 |doi= |url=}}</ref><ref name="pmid8589284">{{cite journal |vauthors=Kalluri R, Wilson CB, Weber M, Gunwar S, Chonko AM, Neilson EG, Hudson BG |title=Identification of the alpha 3 chain of type IV collagen as the common autoantigen in antibasement membrane disease and Goodpasture syndrome |journal=J. Am. Soc. Nephrol. |volume=6 |issue=4 |pages=1178–85 |date=October 1995 |pmid=8589284 |doi= |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Goodpasture syndrome]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemolytic uremic syndrome]]<ref name="pmid15728781">{{cite journal |vauthors=Noris M, Remuzzi G |title=Hemolytic uremic syndrome |journal=J. Am. Soc. Nephrol. |volume=16 |issue=4 |pages=1035–50 |date=April 2005 |pmid=15728781 |doi=10.1681/ASN.2004100861 |url=}}</ref><ref name="pmid27989322">{{cite journal |vauthors=Goodship TH, Cook HT, Fakhouri F, Fervenza FC, Frémeaux-Bacchi V, Kavanagh D, Nester CM, Noris M, Pickering MC, Rodríguez de Córdoba S, Roumenina LT, Sethi S, Smith RJ |title=Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference |journal=Kidney Int. |volume=91 |issue=3 |pages=539–551 |date=March 2017 |pmid=27989322 |doi=10.1016/j.kint.2016.10.005 |url=}}</ref><ref name="pmid25859752">{{cite journal |vauthors=Loirat C, Fakhouri F, Ariceta G, Besbas N, Bitzan M, Bjerre A, Coppo R, Emma F, Johnson S, Karpman D, Landau D, Langman CB, Lapeyraque AL, Licht C, Nester C, Pecoraro C, Riedl M, van de Kar NC, Van de Walle J, Vivarelli M, Frémeaux-Bacchi V |title=An international consensus approach to the management of atypical hemolytic uremic syndrome in children |journal=Pediatr. Nephrol. |volume=31 |issue=1 |pages=15–39 |date=January 2016 |pmid=25859752 |doi=10.1007/s00467-015-3076-8 |url=}}</ref>
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemolytic uremic syndrome]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
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! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Nephrolithiasis]]<ref name="pmid23283137">{{cite journal |vauthors=Fwu CW, Eggers PW, Kimmel PL, Kusek JW, Kirkali Z |title=Emergency department visits, use of imaging, and drugs for urolithiasis have increased in the United States |journal=Kidney Int. |volume=83 |issue=3 |pages=479–86 |date=March 2013 |pmid=23283137 |pmc=3587650 |doi=10.1038/ki.2012.419 |url=}}</ref><ref name="pmid26349951">{{cite journal |vauthors=Singh P, Enders FT, Vaughan LE, Bergstralh EJ, Knoedler JJ, Krambeck AE, Lieske JC, Rule AD |title=Stone Composition Among First-Time Symptomatic Kidney Stone Formers in the Community |journal=Mayo Clin. Proc. |volume=90 |issue=10 |pages=1356–65 |date=October 2015 |pmid=26349951 |pmc=4593754 |doi=10.1016/j.mayocp.2015.07.016 |url=}}</ref><ref name="pmid14960744">{{cite journal |vauthors=Teichman JM |title=Clinical practice. Acute renal colic from ureteral calculus |journal=N. Engl. J. Med. |volume=350 |issue=7 |pages=684–93 |date=February 2004 |pmid=14960744 |doi=10.1056/NEJMcp030813 |url=}}</ref>
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Revision as of 15:55, 23 July 2018

Differential Diagnosis

Abbreviations: ABG = Arterial blood gases, BUN = Blood urea nitrogen, CBC = Complete blood count, CT = Computed tomography, CRP = C - reactive protein, ECG = Electrocardiogram, ESR = Erythrocyte sedimentation rate, IVP = Intravenous pyelography, KFT = Kidney function test, GI = Gastrointestinal, GFR = Glomerular filtration rate, MRI = Magnetic resonance imaging, PT = Prothrombin time

Etiology Clinical manifestations Paraclinical findings Comments
Symptoms and signs Lab findings Imaging
Fatigue/

Lethargy

Thirst Dizziness/

Confusion

Muscle weakness/

cramp

Somatic/

visceral pain

Vomiting Diarrhea Tachypnea Edema Blood indices Renal Funtion test Electrolytes Urine analysis ABG Other Ultrasound X-ray CT MRI Other
Prerenal causes Alcohol poisoning + - +/- - +/- + +/- - - PT BUN, ↑Cr (isopropyl alcohol) Na Not applicable HCO3 LFT Not applicable Not applicable Not applicable Not applicable - Thiamine must be given to prevent Wernicke's encephalopathy
Aspergillosis +/- - - - - - - +/- - Not applicable Not applicable Not applicable Not applicable Not applicable Allergy test, ↑IgE (>1000 IU/dl), Direct visualization of fungal hyphae Not applicable Pulmonary infiltrates, Mucus plug, Mass in the upper lobe surrounded by a crescent of air, Solitary or multiple cavities Halo sign, Wedge-shaped pulmonary infarction, Granuloma Not applicable - Polymerase chain reaction (PCR)
Cholera[1] +/- + - - - +/- + - - Leukocytosis, ↑HCT BUN, ↑Cr Na, ↑Ca, ↑Mg Not applicable Lactate, ↓HCO3 Stool PCR, Stool culture, Serotyping Not applicable Not applicable Not applicable Not applicable - -
Congestive heart failure (CHF) + - - - - - + - + Anemia, Leukocytosis BUN, ↑Cr Na, ↑K Not applicable Lactate, ↓HCO3, BNP, ↑Troponin Cardiomegaly, Pulmonary hypertension, Pleural effusions Pulmonary edema Not applicable Valvular heart disease Decreased ejection fraction in echocardiography, Heart function and damage in nuclear imaging -
Dehydration + + - +/- - +/- +/- - - Not applicable BUN, ↑Cr Na, ↑K, ↓Cl Ketones and glucose, ↑Urine specific gravity Lactate, ↓HCO3 Hypoglycemia Not applicable Not applicable Not applicable Not applicable - -
Diarrhea and/or vomiting +/- +/- - - - + + - - Leukocytosis with predominant neutrophilia, ↑ ESR Not applicable Not applicable Ketones, Organic acids, Porphobilinogen, Aminolevulinic acid Not applicable Stool anion gap, Stool pH < 5.5, Stool culture, Serotyping, Enzyme immunoassay (rotavirus or adenovirus), LFT, Amylase, Lipase Normal Not applicable Not applicable Not applicable - -
Drugs/toxins +/- +/- +/- +/- +/- +/- +/- +/- +/- Not applicable BUN, ↑Cr, ↑CK K, ↓Mg, ↓Ca, ↓P Ingested drug, Glucose, Aminoacid, Phosphate, Ketone, Hyaline cast, RBC Lactate, Metabolic acidosis Toxicology, Rapid immunoassay Nephropathy Radioopaque substances, Ingested drug packets Not applicable Not applicable - -
Esophageal varices bleeding +/- - - - +/- - - - - Normocytic normochromic anemia BUN, ↑Cr Not applicable Not applicable Not applicable Not applicable Velocity and direction of portal flow Abnormal opacities outside ofesophageal wall, Posterior mediastinal or intraparenchymal mass, Dilated azygous vein Entire portal venous system Portrays esophageal varices as flow voids Portal hypertension and esophageal varices in positron emission tomography, Flexible endoscope, Barium swallow of snake-like filling defects -
Heart disease +/- - - - - - - +/- +/- ESR and CRP BUN, ↑Cr Not applicable Not applicable Not applicable Throat culture, Rapid streptococcal antigen test, Hyperoxia test, Pulse oximetry Not applicable Cardiomegaly, Dextrocardia Not applicable Not applicable Ventricular dysfunction, Left and right ventricular hypertrophy, Valvular disease in echocardiography -
Hemorrhage - - - - - - - - - Normocytic normochromic anemia, ↑PT, ↑PTT BUN, ↑Cr Na, ↑Cl, ↓Ca Not applicable Metabolic acidosis Not applicable Peritoneal cavity fluid in FAST Bilateral opacities in the lung field, Hemothorax, Hemoperitoneum, Ruptured abdominal aortic aneurysm Intrathoracic, intra-abdominal, and retroperitoneal bleeding Not applicable Source of bleeding in the upper GI in EGD, Angiography -
Hemolysis +/- - - - - - - - - Thrombocytopenia, Microcytic hypochromic anemia, ↑RDW, ↑Retic count Not applicable Not applicable Not applicable Not applicable LDH, ↓Haptoglobin, ↑Unconjugated bilirubin Hepatomegaly,Splenomegaly Not applicable Not applicable Not applicable - -
Etiology Fatigue/

Lethargy

Thirst Dizziness/

Confusion

Muscle weakness/

cramp

Somatic/

visceral pain

Vomiting Diarrhea Tachypnea Edema Blood indices Renal Funtion test Electrolytes Urine analysis ABG Other Ultrasound X-ray CT MRI Other Comments
Hepatorenal syndrome +/- - - - +/- +/- - - +/- Leukocytosis, ↑PT GFR, ↑BUN, ↑Cr Na Proteinuria, Na < 10 mEq/L, Urine osmolality > plasma osmolality Not applicable Alpha feto-protein, Cryoglobulinemia Exclude hydronephrosis and intrinsic renal disease Not applicable Not applicable Not applicable Right ventricular preload, ventricular filling pressures, and cardiac function in echocardiography -
Ischemic cardiomyopathy +/- - - - - - - +/- +/- Anemia Cr Na, ↓K, ↓Mg Not applicable Not applicable Troponin, Creatine kinase, Creatine kinase - MB, BNP Not applicable Abnormal cardiac silhouette Biventricular volume, Wall motion abnormality, Myocardial perfusion, Hypertrophic cardiomyopathy Mid-wall fibrosis in MRI Ejection fraction ≤35%, Pulmonary embolism, Right ventricular dilation or pericardial effusion with tamponade in echocardiography -
Liver cirrhosis +/- - +/- +/- +/- - - - +/- Not applicable Not applicable Not applicable Not applicable Not applicable LFT, Aspartate aminotransferase to platelet ratio, FibroTest/FibroSure, Hepascore, FibroSpectatio Portal blood flow velocity, Hepatic artery enlargement, Multifocal lesions or masses, Hepatic contour, Ascites, Splenomegaly Bowel perforation, Gynecomastia, Azygos vein enlargement, Pleural effusion Morphologic changes in the liver, Collaterals and shunts, Hyperattenuating nodule of hepatocellular carcinoma, Portal vein thrombosis Vacular patency, Tumor invasion, Portal vein thrombosis, Steatosis Hepatic function and portal hypertension in nuclear imaging, Hepatic perfusion and the development of shunts and tumors in angiography Irreversible and a transplant is usually needed
Malignant hypertension +/- - + - - +/- - +/- +/- Microangiopathic hemolytic anemia BUN, ↑Cr Na, ↑K, ↑P Proteinuria, Microscopic hematuria Acidosis Cardiac enzymes, Urinary catecholamines, TSH, ↑Renin Not applicable Cardiomegaly, Pulmonary edema, Rib notching, Aortic coarctation, Mediastinal widening, Aortic dissection Not applicable Not applicable Left atrial enlargement and left ventricular hypertrophy in echocardiography -
Myocarditis +/- - - - +/- - - +/- - Leukocytosis (eosinophilia),↑ESR and CRP Not applicable Not applicable Not applicable Not applicable Cardiac enzymes, Viral antibodies Not applicable Not applicable Not applicable Inflammatory edema, Degree of scarring Endomyocardial biopsy, Echocardiography, Scintigraphy Not applicable
Peritonitis +/- - +/- - +/- +/- +/- - - Leukocytosis Not applicable Not applicable Not applicable Not applicable Ascitic fluid neutrophil count > 500 cells/µL Not applicable Not applicable Not applicable Not applicable - -
Polycythemia +/- - - - - - - +/- - RBC, ↑HCT, ↑HGB, Thrombocytosis, Leukocytosis, ↑PT and aPTT Erythropoietin Not applicable Not applicable Not applicable Hyperuricemia Splenomegaly Not applicable Not applicable Not applicable - Phlebotomy is the usual treatment
Respiratory distress syndrome + - +/- - - - - + - Not applicable Not applicable Not applicable Not applicable Metabolic and respiratory acidosis Pulse oximetry Not applicable Bilateral, diffuse, reticular granular or ground-glass appearance +/- Cardiomegaly Not applicable Not applicable Patent ductus arteriosus in echocardiography -
Shock +/- +/- +/- +/- +/- +/- - +/- - HCT, ↑PT and aPTT, Eosinophilia, Leukocytosis GFR, ↑BUN, ↑Cr Not applicable Not applicable Lactate LFT, ↑BNP, ↑Troponin, D-dimer, Fibrinogen Pulmonary embolism, Pericardial effusion, Cardiac tamponade, Pneumothorax, Thoracic or abdominal aortic aneurysm in RUSH (Rapid Ultrasound for Shock and Hypotension) Pneumonia, Pneumothorax, Pulmonary edema, Widened mediastinum, Free air under the diaphragm Traumatic brain injury, Stroke, Spinal injury, Pneumonia, Pneumothorax, Ruptured aneurysm, Aortic dissection, Pulmonary embolism Not applicable - -
Toxic megacolon +/- +/- +/- - + + +/- - - Leukocytosis, Anemia, ↑ESR and CRP BUN, ↑Cr Na Not applicable Not applicable Loss of haustra, Hypoechoic and thick bowel walls, Dilated colon > 6cm, Dilatation of ileal loops Dilated colon, Free intraperitoneal air Bowel perforation, Abscess Not applicable Not applicable Endoscopy and colonoscopy -
Etiology Fatigue/

Lethargy

Thirst Dizziness/

Confusion

Muscle weakness/

cramp

Somatic/

visceral pain

Vomiting Diarrhea Tachypnea Edema Blood indices Renal Funtion test Electrolytes Urine analysis ABG Other Ultrasound X-ray CT MRI Other Comments
Renal causes Acute interstitial nephritis +/- - +/- - +/- +/- +/- +/- +/- Eosinophilia BUN, ↑Cr, ↑FENa Not applicable Eosinophiluria, Sterile pyuria, Microscopic hematuria, Proteinuria Not applicable ↑Total IgG, ↑IgG4 Normal-sized kidneys Not applicable Not applicable Not applicable - History of long term analgesic use
Acute tubular necrosis +/- - - - - +/- - - +/- Anemia BUN, ↑Cr, ↑FENa Na, ↑K, ↑Mg, ↑P, ↓Ca Pigmented, muddy brown, granular casts Not applicable Not applicable Obstructive uropathy, Renal size, Cortical thickness, Hydronephrosis Nephrolithiasis Nephrolithiasis, Area of obstruction Nephrolithiasis, Area of obstruction Loss of tubular cells or the denuded tubules, Swollen tubular cells, Loss of the cell brush border in renal biopsy Furosemide stress testing for staging
Cancer + - - - +/- +/- - - +/- Normocytic or microcytic anemia, Leukocytosis or lymphocytosis, ↑Reticulocytes, Thrombocytopenia GFR, ↑BUN, ↑Cr, ↓Erythropoietin Na, ↑K, ↓Mg, ↑P, ↓Ca Gross hematuria Not applicable LFT Fluid collection and morphological change, Flank mass Calcification and widened mediastinum, Filling defects in barium contrast Metastasis and staging, Cystic and solid masses, Lymph node, renal vein, and inferior vena cava involvement Soft tissue invasion and staging Malignant cystic lesions percutaneous cyst puncture Renal cell carcinoma types: Clear cell (75%), Chromophilic (15%), Chromophobic (5%), Oncocytoma (3%), Collecting duct (2%)
Congenital kidney disease

- Agenesis

- Dysplasia

- Hypoplasia

- Polycystic

+/- - - - +/- +/- - - +/- HCT GFR P, ↓Ca Microalbuminuria, Uricosuria Not applicable Genetic testing forADPKD2 Visualization of kidney cysts Small kidney cysts (0.5 cm) Kidney size, Intracranial aneurysms Not applicable - -
End stage renal disease + - - - +/- - - - + Anemia GFR, ↑BUN, ↑Cr K Hypoalbuminuria HCO3 Phosphate, 25-hydroxy vitamin D, Alkaline phosphatase, Parathyroid hormone Hydronephrosis, Retroperitoneal fibrosis, Enlarged or shrunken kidneys Renal masses, stones, and cysts Renal vein thrombosis, Renal artery stenosis in magnetic resonance angiography Percutaneous renal biopsy -
Endogenous toxins

- Hemoglobin

- Myoglobin

- Uric acid

+/- - +/- + - +/- - - +/- Anemia, Thrombocytopenia GFR, ↑BUN, ↑Cr K, ↑Urate, ↓Ca Uricosuria, Hematuria, Myoglobinuria, Casts Not applicable Creatine kinase > 1000 U/L Malignant or cystic lesions, Hydronephrosis, Nephrocalcinosis, Urolithiasis Not applicable Urolithiasis, Wilms tumor, Polycystic kidney disease Not applicable Ureter or bladder abnormality in voiding cystourethrography -
Glomerulonephritis +/- - - - - - - - + Pleocytosis, Anemia, Leukocytosis, ↑ESR BUN, ↑Cr Not applicable Specific gravity > 1.020, Proteinuria, Hematuria, Red blood cell casts, White blood cell casts, Cellular casts, Oval fat bodies Not applicable Not applicable C3, ↑C4, ↑CH50, Blood and tissue culture, Antinuclear antibodies, Cryoglobulins,Hepatitis B and C serologies, Antineutrophil cytoplasmic antibody (ANCA) Kidney size, Echogenicity of the renal cortex, Obstruction, Degree of fibrosis Pulmonary congestion Visceral abscesses - Renal biopsy, Light and electron microscopy, Immunofluorescence aid diagnosis
Goodpasture syndrome +/- - - - - - - +/- +/- Anemia, Leukocytosis, ↑ESR BUN, ↑Cr Not applicable Low-grade proteinuria, Gross or microscopic hematuria, RBC casts Not applicable Anti– glomerular basement membrane antibody Antineutrophilic cytoplasmic antibody Not applicable Bilateral, basal, patchy parenchymal consolidations Not applicable Not applicable Diffuse alveolar hemorrhage in pulmonary biopsy -
Hemolytic uremic syndrome +/- - +/- +/- +/- + + - +/- Severe anemia, Thrombocytopenia, ↑ aPTT BUN, ↑Cr Not applicable Mild proteinuria, Red blood cells, Red blood cell casts Not applicable Schistocytes, ↑FDP and D-dimer, ↑ Bilirubin, ↑LDH, ↓Haptoglobin, Stool culture (for E coli 0157:H7 or shigella), ↓ADAMTS-13 activity Ruling out obstruction Not applicable Not applicable Not applicable Diffuse thickening of the glomerular capillary wall, Swelling of endothelial cells, Fibrin thrombi in renal biopsy -
Nephrolithiasis - - - - +/- +/- - - - Mild leukocytosis, ↑CRP BUN, ↑Cr Na, ↑K, ↑P, ↑Ca, ↑Urate Gross or microscopic hematuria, Red blood cells, Urinary crystals of calcium oxalate, uric acid, or cystine, Hypercalciuria, Urinary pH > 7 in struvite stones (Proteus, Pseudomonas, Klebsiella), Urinary pH < 5 in uric acid stones HCO3, Renal tubular acidosis - All types of stones are visible, Hydronephrosis, Abdominal aortic aneurysm, Cholelithiasis Calcium - containing stones, Uric acid or cystine stones, Stone movement Stone density, size and composition, Hydronephrosis, Nephromegaly, Perinephric fat streaking Not applicable Intravenous pyelography (IVP), Renal tomography, Nuclear renal scan -
  1. Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB (January 1974). "Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum". J. Infect. Dis. 129 (1): 45–52. PMID 4809112.