Hemolytic-uremic syndrome classification: Difference between revisions

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Revision as of 18:13, 2 August 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

HUS may be classified according etiology into 4 subtypes including diarrhoea-associated HUS, non-diarrhea-associated HUS (D−HUS), Streptococcus pneumoniae‐associated HUS, diacylglycerol kinase‐ε (DGKE)‐associated HUS.

Classification

Hemolytic-Uremic syndrome (HUS) may be classified as follows:

Typical Or Diarrhea Related

Shiga-Toxin producing E.Coli/ Shigella infection

Atypical or Non Diarrheal

Primary Causes

Complement Factor abnormalities
- Factor H Defeciency (Autosomal Dominant)
- Factor I Defeciency (Acquired antibody mediated)
- Membrane co-factor protein Defeciency
- Factor B Overactivity (Complement Factor B mutation)

References

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@@ Line 7: / Line 7: @@
 ==Classification==
-Hemolytic uremic syndrome (HUS) may be classified according to diarrhea-associated  into subtypes :<ref name=":0">{{Cite journal
+Hemolytic-Uremic syndrome (HUS) may be classified as follows:
- | author = [[Gaute Reier Jenssen]], [[Eirik Hovland]], [[Anna Bjerre]], [[Hans-Jacob Bangstad]], [[Karin Nygard]] & [[Line Vold]]
- | title = Incidence and etiology of hemolytic-uremic syndrome in children in Norway, 1999-2008--a retrospective study of hospital records to assess the sensitivity of surveillance
+=== '''Typical Or Diarrhea Related''' ===
- | journal = [[BMC infectious diseases]]
+* Shiga-Toxin producing E.Coli/ Shigella infection
- | volume = 14
- | pages = 265
+=== Atypical or Non Diarrheal ===
- | year = 2014
- | month = May
+==== Primary Causes ====
- | doi = 10.1186/1471-2334-14-265
+* Complement Factor abnormalities
- | pmid = 24884396
+** Factor H Defeciency (Autosomal Dominant)
-}}</ref><ref name="KarpmanLoos2017">{{cite journal|last1=Karpman|first1=Diana|last2=Loos|first2=Sebastian|last3=Tati|first3=Ramesh|last4=Arvidsson|first4=Ida|title=Haemolytic uraemic syndrome|journal=Journal of Internal Medicine|volume=281|issue=2|year=2017|pages=123–148|issn=09546820|doi=10.1111/joim.12546}}</ref>
+** Factor I Defeciency (Acquired antibody mediated)
+** Membrane co-factor protein Defeciency
-*Diarrhoea-associated HUS (D+HUS)
+** Factor B Overactivity (Complement Factor B mutation)
-*Non-diarrhea-associated HUS (D−HUS) that  also called atypical HUS
-*''Streptococcus pneumoniae''‐associated HUS
-*Diacylglycerol kinase‐ε (DGKE)‐associated HUS
 ==References==