Thrombotic thrombocytopenic purpura classification: Difference between revisions
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* '''Hereditary:''' Insertions, deletions, missense, nonsense point mutations and splice site mutations of both alleles of ADAMS13 genes cause decrease in the amount and activity of the enzyme. | * '''Hereditary:''' Insertions, deletions, missense, nonsense point mutations and splice site mutations of both alleles of ADAMS13 genes cause decrease in the amount and activity of the enzyme. | ||
* '''Acquired:''' | * '''Acquired:''' Existence of an inhibitory antibody against ADAMS13 due to variety of conditions. | ||
==References== | ==References== |
Revision as of 17:56, 6 August 2018
Thrombotic thrombocytopenic purpura Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[2]
Overview
Classification
- Hereditary: Insertions, deletions, missense, nonsense point mutations and splice site mutations of both alleles of ADAMS13 genes cause decrease in the amount and activity of the enzyme.
- Acquired: Existence of an inhibitory antibody against ADAMS13 due to variety of conditions.