Thrombocytopenia differential diagnosis: Difference between revisions
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|[[White blood cells|WBC]] changes | |[[White blood cells|WBC]] changes | ||
|[[Red blood cell|RBC]] changes | |[[Red blood cell|RBC]] ([[hemoglobin]]) changes | ||
|other findings | |other findings | ||
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* [[Seizures]] | * [[Seizures]] | ||
* [[Intracranial hemorrhage]] | * [[Intracranial hemorrhage]] | ||
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|<nowiki>-</nowiki> | |<nowiki>-</nowiki> | ||
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| rowspan="3" |'''Dermatologic''' | | rowspan="3" |'''Dermatologic''' | ||
|[[Cholesterol embolism]] | |[[Cholesterol embolism]] | ||
|'''General:''' | |||
* [[fever]], | |||
* [[myalgia]] | |||
* [[Weight loss#Unintentional weight loss|weight loss]] | |||
'''Organ-dependent:''' | |||
Lower extremities | |||
* [[Livedoid vasculitis|livedo reticularis]] | |||
Kidney | |||
* symptoms of [[Renal insufficiency|renal failure]] or [[nephrotic syndrome]] | |||
Gastroinstestinal | |||
* reduced appetite | |||
* nausea and vomiting | |||
* nonspecific [[abdominal pain]] | |||
* [[gastrointestinal hemorrhage]] | |||
Central nervous system | |||
* [[stroke]]-like symptoms | |||
* [[headache]] | |||
* [[amaurosis fugax]] | |||
* [[paraparesis]] | |||
* [[cauda equina syndrome]] | |||
* loss of control over the [[bladder]], [[rectum]] and skin sensation around the anus | |||
* [[mononeuropathy]]. | |||
| | | | ||
| ↑/- | |||
|↓/- | |||
| | | | ||
| | : | ||
| | :* ↑ [[Blood urea nitrogen|BUN]] and [[Creatinine|Cr]] in case of renal failure | ||
| | :* ↑ [[Creatine kinase|CPK]] and [[troponin]] in case of myocardial infarction | ||
| | :* [[Occult blood|OB]]+ in case of mesenteric ischemia | ||
:* Peripheral [[eosinophilia]] | |||
:* Urinary [[eosinophilia]] in patients with cholesterol-renal disease | |||
:* [[Complement deficiency|Hypocomplementemia]] | |||
:* ↑ [[Erythrocyte sedimentation rate|ESR]] | |||
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* characteristic [[hypopigmentation]] | * characteristic [[hypopigmentation]] | ||
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Revision as of 11:34, 8 August 2018
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Thrombocytopenia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Thrombocytopenia differential diagnosis On the Web |
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American Roentgen Ray Society Images of Thrombocytopenia differential diagnosis |
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Risk calculators and risk factors for Thrombocytopenia differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Farbod Zahedi Tajrishi, M.D.
Overview
Thrombocytopenia has a broad range of potential causes. While a good history and physical examination can be helpful to diagnose some of these causes such as drug-induced thrombocytopenia, they usually don't suffice and further evaluation is often needed. There are also some useful points that may guide the physician to an appropriate diagnosis. For example, asymptomatic, isolated thrombocytopenia most probably suggests ITP, while thrombocytopenia in critically ill, hospitalized patients is usually suggestive of iatrogenic causes (eg. dilution), platelet consumption, bone marrow suppression from infection/sepsis, or even drug-induced thrombocytopenia. One should consider however, that a wide variety of other conditions such as autoimmune disorders, nutrient deficiencies, thrombotic microangiopathies could all as well cause thrombocytopenia.
Differential Diagnosis
References
- ↑ Infective endocarditis. Wikipedia (2015). https://en.wikipedia.org/wiki/Infective_endocarditis Accessed on September 24, 2015
- ↑ Cohen AT, Dobromirski M, Gurwith MM (2014). "Managing pulmonary embolism from presentation to extended treatment". Thromb Res. 133 (2): 139–48. doi:10.1016/j.thromres.2013.09.040. PMID 24182642.