Stevens-Johnson syndrome epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
*The incidence | *The incidence of SJS is approximately 2-7 per 1000,000 individuals per year.<ref name="pmid2036028">{{cite journal| author=Strom BL, Carson JL, Halpern AC, Schinnar R, Snyder ES, Shaw M et al.| title=A population-based study of Stevens-Johnson syndrome. Incidence and antecedent drug exposures. | journal=Arch Dermatol | year= 1991 | volume= 127 | issue= 6 | pages= 831-8 | pmid=2036028 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2036028 }}</ref> | ||
*The incidences of SJS, SJS-TEN, and TEN were found to be a mean 5.3, 0.8, and 0.4 cases per million children per year in the US<ref name="pmid28285784">{{cite journal| author=Hsu DY, Brieva J, Silverberg NB, Paller AS, Silverberg JI| title=Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States. | journal=J Am Acad Dermatol | year= 2017 | volume= 76 | issue= 5 | pages= 811-817.e4 | pmid=28285784 | doi=10.1016/j.jaad.2016.12.024 | pmc=5502094 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28285784 }}</ref> | |||
*The mean estimated incidences of SJS, SJS/TEN, and TEN were found to be 9.2, 1.6, and 1.9 per million adults per year in the US<ref name="pmid27039263">{{cite journal| author=Hsu DY, Brieva J, Silverberg NB, Silverberg JI| title=Morbidity and Mortality of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in United States Adults. | journal=J Invest Dermatol | year= 2016 | volume= 136 | issue= 7 | pages= 1387-1397 | pmid=27039263 | doi=10.1016/j.jid.2016.03.023 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27039263 }}</ref> | |||
=== | |||
*The | |||
*The | |||
===Case-fatality rate/Mortality rate=== | ===Case-fatality rate/Mortality rate=== | ||
* | *Between years 2009-2012, the Mean adjusted mortality was 4.8% for SJS, 19.4% for SJS/TEN, and 14.8% for TEN<ref name="pmid270392632">{{cite journal| author=Hsu DY, Brieva J, Silverberg NB, Silverberg JI| title=Morbidity and Mortality of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in United States Adults. | journal=J Invest Dermatol | year= 2016 | volume= 136 | issue= 7 | pages= 1387-1397 | pmid=27039263 | doi=10.1016/j.jid.2016.03.023 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27039263 }}</ref> | ||
===Age=== | ===Age=== | ||
*Patients of all age groups may develop | *Patients of all age groups may develop SJS. | ||
===Race=== | ===Race=== | ||
* | *The incidence of SJS might be higher in Non White/Multiracial people as compared to White{{cite web |url=https://doi.org/10.1016/j.jid.2016.03.023 |title=Redirecting |format= |work= |accessdate=}} | ||
===Gender=== | ===Gender=== | ||
* | *Women are more commonly affected by SJS than males{{cite web |url=https://doi.org/10.1016/j.jid.2016.03.023 |title=Redirecting |format= |work= |accessdate=}}. | ||
=== | |||
==References== | ==References== |
Revision as of 21:34, 29 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Epidemiology and Demographics
Incidence
- The incidence of SJS is approximately 2-7 per 1000,000 individuals per year.[1]
- The incidences of SJS, SJS-TEN, and TEN were found to be a mean 5.3, 0.8, and 0.4 cases per million children per year in the US[2]
- The mean estimated incidences of SJS, SJS/TEN, and TEN were found to be 9.2, 1.6, and 1.9 per million adults per year in the US[3]
Case-fatality rate/Mortality rate
- Between years 2009-2012, the Mean adjusted mortality was 4.8% for SJS, 19.4% for SJS/TEN, and 14.8% for TEN[4]
Age
- Patients of all age groups may develop SJS.
Race
- The incidence of SJS might be higher in Non White/Multiracial people as compared to White"Redirecting".
Gender
- Women are more commonly affected by SJS than males"Redirecting"..
References
- ↑ Strom BL, Carson JL, Halpern AC, Schinnar R, Snyder ES, Shaw M; et al. (1991). "A population-based study of Stevens-Johnson syndrome. Incidence and antecedent drug exposures". Arch Dermatol. 127 (6): 831–8. PMID 2036028.
- ↑ Hsu DY, Brieva J, Silverberg NB, Paller AS, Silverberg JI (2017). "Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States". J Am Acad Dermatol. 76 (5): 811–817.e4. doi:10.1016/j.jaad.2016.12.024. PMC 5502094. PMID 28285784.
- ↑ Hsu DY, Brieva J, Silverberg NB, Silverberg JI (2016). "Morbidity and Mortality of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in United States Adults". J Invest Dermatol. 136 (7): 1387–1397. doi:10.1016/j.jid.2016.03.023. PMID 27039263.
- ↑ Hsu DY, Brieva J, Silverberg NB, Silverberg JI (2016). "Morbidity and Mortality of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in United States Adults". J Invest Dermatol. 136 (7): 1387–1397. doi:10.1016/j.jid.2016.03.023. PMID 27039263.