Hemolytic-uremic syndrome historical perspective: Difference between revisions

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*In 1983,  Karmali and colleagues were the first to discover the association between Escherichia coli and the development of [[HUS]].<ref name=":0" />
*In 1983,  Karmali and colleagues were the first to discover the association between Escherichia coli and the development of [[HUS]].<ref name=":0" />
*The association between [[Shiga toxin|Shiga-toxin]]-producing bacteria and [[Hemolytic-uremic syndrome|HUS]] was made 35 years ago.<ref name=":0" />
*The association between [[Shiga toxin|Shiga-toxin]]-producing bacteria and [[Hemolytic-uremic syndrome|HUS]] was made 35 years ago.<ref name=":0" />
*In [year], [[membrane cofactor protein]] (MCP), complement factor H (CFH) and  factor I (IF) mutations were implicated in the pathogenesis of non–Shiga toxin–associated HUS<ref>{{Cite journal
| author = [[Jessica Caprioli]], [[Marina Noris]], [[Simona Brioschi]], [[Gaia Pianetti]], [[Federica Castelletti]], [[Paola Bettinaglio]], [[Caterina Mele]], [[Elena Bresin]], [[Linda Cassis]], [[Sara Gamba]], [[Francesca Porrati]], [[Sara Bucchioni]], [[Giuseppe Monteferrante]], [[Celia J. Fang]], [[M. K. Liszewski]], [[David Kavanagh]], [[John P. Atkinson]] & [[Giuseppe Remuzzi]]
| title = Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome
| journal = [[Blood]]
| volume = 108
| issue = 4
| pages = 1267–1279
| year = 2006
| month = August
| doi = 10.1182/blood-2005-10-007252
| pmid = 16621965
}}</ref>


==Outbreaks==
==Outbreaks==

Revision as of 16:09, 20 August 2018

Hemolytic-uremic syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Historical Perspective

Discovery

  • HUS was first described by Gasser and colleagues in paper published in 1955.[1][2]
  • In 1983, Karmali and colleagues were the first to discover the association between Escherichia coli and the development of HUS.[2]
  • The association between Shiga-toxin-producing bacteria and HUS was made 35 years ago.[2]

Outbreaks

There have been several outbreaks of HUS, which are summarized below:

Shiga toxin-producing (STEC) Escherichia coli O157

Landmark Events in the Development of Treatment Strategies

In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

Impact on Cultural History

Famous Cases

The following are a few famous cases of disease name:

References

  1. A. Schieppati, P. Ruggenenti, R. P. Cornejo, F. Ferrario, G. Gregorini, P. Zucchelli, E. Rossi & G. Remuzzi (1992). "Renal function at hospital admission as a prognostic factor in adult hemolytic uremic syndrome. The Italian Registry of Haemolytic Uremic Syndrome". Journal of the American Society of Nephrology : JASN. 2 (11): 1640–1644. PMID 1610985. Unknown parameter |month= ignored (help)
  2. 2.0 2.1 2.2 Phillip I. Tarr, Carrie A. Gordon & Wayne L. Chandler (2005). "Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome". Lancet (London, England). 365 (9464): 1073–1086. doi:10.1016/S0140-6736(05)71144-2. PMID 15781103. Unknown parameter |month= ignored (help)

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