Spondyloarthropathy epidemiology and demographics: Difference between revisions
| Line 1: | Line 1: | ||
==epidemiology and demographics== | ==epidemiology and demographics== | ||
Spondyloarthropathy (SpA) is a world wide disease but it has been seen mostly throughout Europe, Asia, North Africa, and North America, which are the places for presence of HLA-B27. SpA and HLA-B27 is somehow absent among genetically unmixed native populations of South Africa and Australia. | {{Spondyloarthropathy}}Spondyloarthropathy (SpA) is a world wide disease but it has been seen mostly throughout Europe, Asia, North Africa, and North America, which are the places for presence of HLA-B27. SpA and HLA-B27 is somehow absent among genetically unmixed native populations of South Africa and Australia. | ||
Here are some labeled data that shows not only the prevalence of spondyloarthropathies but also the prevalence of HLA-B27 and its subtype. | Here are some labeled data that shows not only the prevalence of spondyloarthropathies but also the prevalence of HLA-B27 and its subtype. | ||
| Line 60: | Line 60: | ||
| style="padding: 5px 5px; background: #DCDCDC; " align="center" |.. | | style="padding: 5px 5px; background: #DCDCDC; " align="center" |.. | ||
|} | |} | ||
{| style="border: 3px; font-size; 190%; margin: 1px; width: 800px" align="center" | {| style="border: 3px; font-size; 190%; margin: 1px; width: 800px" align="center" | ||
| Line 92: | Line 90: | ||
|- | |- | ||
|} | |} | ||
.. | .. | ||
Latest revision as of 12:04, 29 August 2018
epidemiology and demographics
|
Spondyloarthropathy Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Spondyloarthropathy epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Spondyloarthropathy epidemiology and demographics |
|
Spondyloarthropathy epidemiology and demographics in the news |
|
Risk calculators and risk factors for Spondyloarthropathy epidemiology and demographics |
Spondyloarthropathy (SpA) is a world wide disease but it has been seen mostly throughout Europe, Asia, North Africa, and North America, which are the places for presence of HLA-B27. SpA and HLA-B27 is somehow absent among genetically unmixed native populations of South Africa and Australia.
Here are some labeled data that shows not only the prevalence of spondyloarthropathies but also the prevalence of HLA-B27 and its subtype.
| Prevalence of AS and related spondyloarthropathies throughout different populations | |||||
|---|---|---|---|---|---|
| populations | B27 frequency | Prevalence of AS | Prevalence of SpA
(including AS) | ||
| General population | B27+ part of population | General population | B27+ part of population | ||
| Eskimos (Alaska) | 40% | 0.4% | .. | 2.5% | .. |
| Skimos (Alaska & Siberia) & Chukcki | 25-40% | .. | 1.6% | 2-3.4% | 4.2% |
| Samis (Lapland) | 24% | 1.8% | 6.8% | .. | .. |
| Northern Norway | 10-16% | 1.4% | .. | .. | .. |
| Mordovia | 16% | 0.5% | .. | .. | .. |
| Europe (Western) | 8% | 0.2% | 2% | .. | .. |
| Basic HLA-B27 subtypes and their geographical distribution | ||
|---|---|---|
| HLA-B27 subtype | Geographical appearance | Assocoation |
| HLA-B*2702 | Mediterranean populations | Association with AS |
| HLA-B*2704 | Major subtype in Chinese and Japanese populations | Association with SpA |
| HLA-B*2705 | Major subtype in Caucasians | Strong association with AS |
| HLA-B*2706 | Healthy populations in Southeast Asia | Very weak association with SpA |
| HLA-B*2709 | Healthy population of Sardinia | AS sparing |
..