Thrombotic thrombocytopenic purpura risk factors: Difference between revisions
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===Less Common Risk Factors=== | ===Less Common Risk Factors=== | ||
Less common risk factors in the development of TTP include:<ref name="pmid20409074">{{cite journal |vauthors=Visagie GJ, Louw VJ |title=Myocardial injury in HIV-associated thrombotic thrombocytopenic purpura (TTP) |journal=Transfus Med |volume=20 |issue=4 |pages=258–64 |date=August 2010 |pmid=20409074 |doi=10.1111/j.1365-3148.2010.01006.x |url=}}</ref> | Less common risk factors in the development of TTP include:<ref name="pmid20409074">{{cite journal |vauthors=Visagie GJ, Louw VJ |title=Myocardial injury in HIV-associated thrombotic thrombocytopenic purpura (TTP) |journal=Transfus Med |volume=20 |issue=4 |pages=258–64 |date=August 2010 |pmid=20409074 |doi=10.1111/j.1365-3148.2010.01006.x |url=}}</ref><ref name="pmid25483393">{{cite journal |vauthors=Jodele S, Laskin BL, Dandoy CE, Myers KC, El-Bietar J, Davies SM, Goebel J, Dixon BP |title=A new paradigm: Diagnosis and management of HSCT-associated thrombotic microangiopathy as multi-system endothelial injury |journal=Blood Rev. |volume=29 |issue=3 |pages=191–204 |date=May 2015 |pmid=25483393 |pmc=4659438 |doi=10.1016/j.blre.2014.11.001 |url=}}</ref> | ||
*HIV infection | *HIV infection | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Risk Factors
Common Risk Factors
Common risk factors in the development of TTP may be occupational, environmental, genetic, and viral.
Common risk factors in the development of TTP include:[1][2][3]
- Black ethnicity
- Female gender
- SLE
- Obesity
- Pregnancy (third trimester)
- Cancer therapies
Less Common Risk Factors
Less common risk factors in the development of TTP include:[4][5]
- HIV infection
- Bone marrow transplantation
- Antiplatelet agents
- Quinine
References
- ↑ Martino S, Jamme M, Deligny C, Busson M, Loiseau P, Azoulay E, Galicier L, Pène F, Provôt F, Dossier A, Saheb S, Veyradier A, Coppo P (2016). "Thrombotic Thrombocytopenic Purpura in Black People: Impact of Ethnicity on Survival and Genetic Risk Factors". PLoS ONE. 11 (7): e0156679. doi:10.1371/journal.pone.0156679. PMC 4934773. PMID 27383202.
- ↑ Nicol, Kathleen K.; Shelton, Brent J.; Knovich, Mary Ann; Owen, John (2003). "Overweight individuals are at increased risk for thrombotic thrombocytopenic purpura". American Journal of Hematology. 74 (3): 170–174. doi:10.1002/ajh.10418. ISSN 0361-8609.
- ↑ Scully M, Thomas M, Underwood M, Watson H, Langley K, Camilleri RS, Clark A, Creagh D, Rayment R, Mcdonald V, Roy A, Evans G, McGuckin S, Ni Ainle F, Maclean R, Lester W, Nash M, Scott R, O Brien P (July 2014). "Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes". Blood. 124 (2): 211–9. doi:10.1182/blood-2014-02-553131. PMID 24859360.
- ↑ Visagie GJ, Louw VJ (August 2010). "Myocardial injury in HIV-associated thrombotic thrombocytopenic purpura (TTP)". Transfus Med. 20 (4): 258–64. doi:10.1111/j.1365-3148.2010.01006.x. PMID 20409074.
- ↑ Jodele S, Laskin BL, Dandoy CE, Myers KC, El-Bietar J, Davies SM, Goebel J, Dixon BP (May 2015). "A new paradigm: Diagnosis and management of HSCT-associated thrombotic microangiopathy as multi-system endothelial injury". Blood Rev. 29 (3): 191–204. doi:10.1016/j.blre.2014.11.001. PMC 4659438. PMID 25483393.