Thrombotic thrombocytopenic purpura classification: Difference between revisions
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==Classification== | ==Classification== | ||
TTP may be classified into several subtypes based on: | TTP may be classified into several subtypes based on: | ||
1.autoantibody against ADAMTS13 | |||
Congenital TTP | *Congenital TTP | ||
Inherited TTP | *Inherited TTP | ||
familial TTP | *familial TTP | ||
Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 | *Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 | ||
#gene mutations of ADAMTS13 | #gene mutations of ADAMTS13 | ||
Revision as of 18:01, 12 September 2018
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Thrombotic thrombocytopenic purpura Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
Classification
TTP may be classified into several subtypes based on: 1.autoantibody against ADAMTS13
- Congenital TTP
- Inherited TTP
- familial TTP
- Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34
- gene mutations of ADAMTS13
- Hereditary:
- Congenital TTP
- Inherited TTP
- familial TTP
- Upshaw-Schulman syndrome (USS) is an autosomal recessive disease of ADAMTS13 gene on chromosome 9q34 [1].
- Acquired: Existence of an inhibitory antibody against ADAMS13 due to the variety of conditions.
References
- ↑ Yoshihiro Fujimura, Masanori Matsumoto, Hideo Yagi, Akira Yoshioka, Taei Matsui & Koiti Titani (2002). "Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome". International journal of hematology. 75 (1): 25–34. PMID 11843286. Unknown parameter
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