Palmar plantar erythrodysesthesia causes: Difference between revisions
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* Most frequently associated with Doxorubicin (Pegylated liposomal Doxorubicin), 5-Flurouracil, and Cytarabine<ref name="pmid17350337">{{cite journal| author=Webster-Gandy JD, How C, Harrold K| title=Palmar-plantar erythrodysesthesia (PPE): a literature review with commentary on experience in a cancer centre. | journal=Eur J Oncol Nurs | year= 2007 | volume= 11 | issue= 3 | pages= 238-46 | pmid=17350337 | doi=10.1016/j.ejon.2006.10.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17350337 }}</ref>. | * Most frequently associated with Doxorubicin (Pegylated liposomal Doxorubicin), 5-Flurouracil, and Cytarabine<ref name="pmid17350337">{{cite journal| author=Webster-Gandy JD, How C, Harrold K| title=Palmar-plantar erythrodysesthesia (PPE): a literature review with commentary on experience in a cancer centre. | journal=Eur J Oncol Nurs | year= 2007 | volume= 11 | issue= 3 | pages= 238-46 | pmid=17350337 | doi=10.1016/j.ejon.2006.10.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17350337 }}</ref>. | ||
* Methotrexate - even low dose used to treat ALL<ref name="pmid1441532">{{cite journal| author=Wysocki M, Nowaczyk-Michalak A, Pilecki O, Kurylak A, Balcar-Boroń A, Trybuś L| title=[Burgdorf's reaction (painful acral erythema) in patients with acute lymphoblastic leukemia following medium-dose methotrexate therapy]. | journal=Wiad Lek | year= 1992 | volume= 45 | issue= 11-12 | pages= 462-4 | pmid=1441532 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1441532 }}</ref> | * Methotrexate - even low dose used to treat ALL<ref name="pmid1441532">{{cite journal| author=Wysocki M, Nowaczyk-Michalak A, Pilecki O, Kurylak A, Balcar-Boroń A, Trybuś L| title=[Burgdorf's reaction (painful acral erythema) in patients with acute lymphoblastic leukemia following medium-dose methotrexate therapy]. | journal=Wiad Lek | year= 1992 | volume= 45 | issue= 11-12 | pages= 462-4 | pmid=1441532 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1441532 }}</ref> | ||
* Mitotane | * Mitotane<ref name="pmid4276191">{{cite journal| author=Zuehlke RL| title=Erythematous eruption of the palms and soles associated with mitotane therapy. | journal=Dermatologica | year= 1974 | volume= 148 | issue= 2 | pages= 90-2 | pmid=4276191 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4276191 }}</ref> | ||
* PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib | * PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib<ref name="pmid21537373">{{cite journal| author=Farr KP, Safwat A| title=Palmar-plantar erythrodysesthesia associated with chemotherapy and its treatment. | journal=Case Rep Oncol | year= 2011 | volume= 4 | issue= 1 | pages= 229-35 | pmid=21537373 | doi=10.1159/000327767 | pmc=3085037 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21537373 }}</ref> | ||
===Genetics=== | ===Genetics=== | ||
Revision as of 15:04, 7 October 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Several different Chemotherapeutic agents have been associated with acral erythema[1]
Causes
Commonly associated chemotherapeutic agents are listed below:
- Most frequently associated with Doxorubicin (Pegylated liposomal Doxorubicin), 5-Flurouracil, and Cytarabine[2].
- Methotrexate - even low dose used to treat ALL[3]
- Mitotane[4]
- PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib[5]
Genetics
No genetic association has been found as of yet as the data on this condition is limited.
References
- ↑ Baack BR, Burgdorf WH (1991). "Chemotherapy-induced acral erythema". J Am Acad Dermatol. 24 (3): 457–61. PMID 2061446.
- ↑ Webster-Gandy JD, How C, Harrold K (2007). "Palmar-plantar erythrodysesthesia (PPE): a literature review with commentary on experience in a cancer centre". Eur J Oncol Nurs. 11 (3): 238–46. doi:10.1016/j.ejon.2006.10.004. PMID 17350337.
- ↑ Wysocki M, Nowaczyk-Michalak A, Pilecki O, Kurylak A, Balcar-Boroń A, Trybuś L (1992). "[Burgdorf's reaction (painful acral erythema) in patients with acute lymphoblastic leukemia following medium-dose methotrexate therapy]". Wiad Lek. 45 (11–12): 462–4. PMID 1441532.
- ↑ Zuehlke RL (1974). "Erythematous eruption of the palms and soles associated with mitotane therapy". Dermatologica. 148 (2): 90–2. PMID 4276191.
- ↑ Farr KP, Safwat A (2011). "Palmar-plantar erythrodysesthesia associated with chemotherapy and its treatment". Case Rep Oncol. 4 (1): 229–35. doi:10.1159/000327767. PMC 3085037. PMID 21537373.