Palmar plantar erythrodysesthesia causes: Difference between revisions
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* Mitotane<ref name="pmid4276191">{{cite journal| author=Zuehlke RL| title=Erythematous eruption of the palms and soles associated with mitotane therapy. | journal=Dermatologica | year= 1974 | volume= 148 | issue= 2 | pages= 90-2 | pmid=4276191 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4276191 }}</ref> | * Mitotane<ref name="pmid4276191">{{cite journal| author=Zuehlke RL| title=Erythematous eruption of the palms and soles associated with mitotane therapy. | journal=Dermatologica | year= 1974 | volume= 148 | issue= 2 | pages= 90-2 | pmid=4276191 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4276191 }}</ref> | ||
* PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib<ref name="pmid21537373">{{cite journal| author=Farr KP, Safwat A| title=Palmar-plantar erythrodysesthesia associated with chemotherapy and its treatment. | journal=Case Rep Oncol | year= 2011 | volume= 4 | issue= 1 | pages= 229-35 | pmid=21537373 | doi=10.1159/000327767 | pmc=3085037 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21537373 }}</ref> | * PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib<ref name="pmid21537373">{{cite journal| author=Farr KP, Safwat A| title=Palmar-plantar erythrodysesthesia associated with chemotherapy and its treatment. | journal=Case Rep Oncol | year= 2011 | volume= 4 | issue= 1 | pages= 229-35 | pmid=21537373 | doi=10.1159/000327767 | pmc=3085037 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21537373 }}</ref> | ||
'''<big>Less Common Causes</big>'''<ref name="pmid10071309">{{cite journal| author=Susser WS, Whitaker-Worth DL, Grant-Kels JM| title=Mucocutaneous reactions to chemotherapy. | journal=J Am Acad Dermatol | year= 1999 | volume= 40 | issue= 3 | pages= 367-98; quiz 399-400 | pmid=10071309 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10071309 }}</ref> | |||
* Cisplatin | |||
* Cyclophosphamide | |||
* Daunorubicin | |||
* Doxifluridine | |||
* Etoposide | |||
* Floxuridine | |||
* Hydroxyurea | |||
* Idarubicin | |||
* Lomustine | |||
* Melphalan | |||
* Mercaptopurine | |||
* Mitomycin | |||
* Paclitaxel | |||
* Suramin | |||
* Troxacitabine<ref name="pmid11432895">{{cite journal| author=Hidalgo M, Siu LL, Nemunaitis J, Rizzo J, Hammond LA, Takimoto C et al.| title=Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. | journal=J Clin Oncol | year= 2001 | volume= 19 | issue= 13 | pages= 3267-79 | pmid=11432895 | doi=10.1200/JCO.2001.19.13.3267 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11432895 }}</ref> | |||
* Tegafur | |||
* Vincristine | |||
===Genetics=== | ===Genetics=== | ||
Revision as of 15:16, 7 October 2018
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Palmar plantar erythrodysesthesia Microchapters |
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Differentiating Palmar plantar erythrodysesthesia from other Diseases |
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Diagnosis |
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Treatment |
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Palmar plantar erythrodysesthesia causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Several different Chemotherapeutic agents have been associated with acral erythema[1]
Causes
Commonly associated chemotherapeutic agents are listed below:
- Most frequently associated with Doxorubicin (Pegylated liposomal Doxorubicin), 5-Flurouracil, and Cytarabine[2].
- Methotrexate - even low dose used to treat ALL[3]
- Mitotane[4]
- PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib[5]
Less Common Causes[6]
- Cisplatin
- Cyclophosphamide
- Daunorubicin
- Doxifluridine
- Etoposide
- Floxuridine
- Hydroxyurea
- Idarubicin
- Lomustine
- Melphalan
- Mercaptopurine
- Mitomycin
- Paclitaxel
- Suramin
- Troxacitabine[7]
- Tegafur
- Vincristine
Genetics
No genetic association has been found as of yet as the data on this condition is limited.
References
- ↑ Baack BR, Burgdorf WH (1991). "Chemotherapy-induced acral erythema". J Am Acad Dermatol. 24 (3): 457–61. PMID 2061446.
- ↑ Webster-Gandy JD, How C, Harrold K (2007). "Palmar-plantar erythrodysesthesia (PPE): a literature review with commentary on experience in a cancer centre". Eur J Oncol Nurs. 11 (3): 238–46. doi:10.1016/j.ejon.2006.10.004. PMID 17350337.
- ↑ Wysocki M, Nowaczyk-Michalak A, Pilecki O, Kurylak A, Balcar-Boroń A, Trybuś L (1992). "[Burgdorf's reaction (painful acral erythema) in patients with acute lymphoblastic leukemia following medium-dose methotrexate therapy]". Wiad Lek. 45 (11–12): 462–4. PMID 1441532.
- ↑ Zuehlke RL (1974). "Erythematous eruption of the palms and soles associated with mitotane therapy". Dermatologica. 148 (2): 90–2. PMID 4276191.
- ↑ Farr KP, Safwat A (2011). "Palmar-plantar erythrodysesthesia associated with chemotherapy and its treatment". Case Rep Oncol. 4 (1): 229–35. doi:10.1159/000327767. PMC 3085037. PMID 21537373.
- ↑ Susser WS, Whitaker-Worth DL, Grant-Kels JM (1999). "Mucocutaneous reactions to chemotherapy". J Am Acad Dermatol. 40 (3): 367–98, quiz 399-400. PMID 10071309.
- ↑ Hidalgo M, Siu LL, Nemunaitis J, Rizzo J, Hammond LA, Takimoto C; et al. (2001). "Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies". J Clin Oncol. 19 (13): 3267–79. doi:10.1200/JCO.2001.19.13.3267. PMID 11432895.