Ameloblastoma medical therapy: Difference between revisions

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Revision as of 16:35, 17 October 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

The mainstay of therapy for ameloblastoma is surgery. Adjunctive chemotherapy/radiation/chemoradiation may be required.

The mainstay of therapy for ameloblastoma is surgery resection or enucleation.^[1]

Patients with ameloblastoma are treated with chemotherapy, radiation and chemoradiation.
Patients with ameloblastoma are also treated with curettage and liquid nitrogen have been effective in some cases.

↑ McClary, Andrew C.; West, Robert B.; McClary, Ashley C.; Pollack, Jonathan R.; Fischbein, Nancy J.; Holsinger, Christopher F.; Sunwoo, John; Colevas, A. Dimitrios; Sirjani, Davud (2015). "Ameloblastoma: a clinical review and trends in management". European Archives of Oto-Rhino-Laryngology. 273 (7): 1649–1661. doi:10.1007/s00405-015-3631-8. ISSN 0937-4477.

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 ==Medical Therapy==
-While chemotherapy, radiation therapy, curettage and liquid nitrogen have been effective in some cases of ameloblastoma, surgical resection or enucleation remains the most definitive treatment for this condition. Radiation is ineffective in many cases of ameloblastoma. There have also been reports of sarcoma being induced as the result of using radiation to treat ameloblastoma. Chemotherapy is also often ineffective. However, there is some controversy regarding this[13] and some indication that some ameloblastomas might be more responsive to radiation that previously thought.
+* The mainstay of therapy for ameloblastoma is surgery resection or enucleation.<ref name="McClaryWest2015">{{cite journal|last1=McClary|first1=Andrew C.|last2=West|first2=Robert B.|last3=McClary|first3=Ashley C.|last4=Pollack|first4=Jonathan R.|last5=Fischbein|first5=Nancy J.|last6=Holsinger|first6=Christopher F.|last7=Sunwoo|first7=John|last8=Colevas|first8=A. Dimitrios|last9=Sirjani|first9=Davud|title=Ameloblastoma: a clinical review and trends in management|journal=European Archives of Oto-Rhino-Laryngology|volume=273|issue=7|year=2015|pages=1649–1661|issn=0937-4477|doi=10.1007/s00405-015-3631-8}}</ref>
+* Patients with ameloblastoma are treated with chemotherapy, radiation and chemoradiation.
+* Patients with ameloblastoma are also treated with curettage and liquid nitrogen have been effective in some cases.
 ==References==