Adult T-cell leukemia classification: Difference between revisions
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* The table below lists the adult T-cell leukemia clinical classification details: | * The table below lists the adult T-cell leukemia clinical classification details: | ||
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! style="background: #4479BA; width: 200px; color: #FFFFFF;" |Clinical Variant | |||
! style="background: #4479BA; width: 600px; color: #FFFFFF;" |Description | |||
! style="background: #4479BA; width: 200px; color: #FFFFFF;" | | |||
! style="background: #4479BA; width: 600px; color: #FFFFFF;" | | |||
|- | |- | ||
! align="center" style="background:#DCDCDC;" |Acute adult T-cell leukemia | |||
| align="center" style="background:#F5F5F5;" | | |||
* Leukemic clinical presentation | * Leukemic clinical presentation | ||
* [[Organomegaly]] present | * [[Organomegaly]] present | ||
* Markedly elevated [[lactate dehydrogenase]] ([[LDH]]) level | * Markedly elevated [[lactate dehydrogenase]] ([[LDH]]) level | ||
* [[Hypercalcaemia]] | * [[Hypercalcaemia]] | ||
|- | |- | ||
! align="center" style="background:#DCDCDC;" |[[Chronic adult T-cell leukemia]] | |||
| align="center" style="background:#F5F5F5;" | | |||
* [[Lymphocyte]] count greater than 4×10<sup>9</sup>/L | * [[Lymphocyte]] count greater than 4×10<sup>9</sup>/L | ||
* [[Cutaneous]], [[pulmonary]], and [[hepatic]] involvement | * [[Cutaneous]], [[pulmonary]], and [[hepatic]] involvement | ||
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* Normal [[serum]] [[calcium]] level | * Normal [[serum]] [[calcium]] level | ||
|- | |- | ||
! align="center" style="background:#DCDCDC;" |Smoldering adult T-cell leukemia | |||
| align="center" style="background:#F5F5F5;" | | |||
* [[Cutaneous]] and/or [[pulmonary]] infiltrates | * [[Cutaneous]] and/or [[pulmonary]] infiltrates | ||
* No other organ involvement | * No other organ involvement | ||
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* Normal serum [[Lactate dehydrogenase|LDH]] level | * Normal serum [[Lactate dehydrogenase|LDH]] level | ||
* Normal serum [[calcium]] level | * Normal serum [[calcium]] level | ||
|- | |- | ||
! align="center" style="background:#DCDCDC;" |Adult T-cell lymphoma | |||
| align="left" style="background:#F5F5F5;" | | |||
* [[Organomegaly]] present | * [[Organomegaly]] present | ||
* Less than 1% leukemic cells in the [[circulation]] | * Less than 1% leukemic cells in the [[circulation]] |
Revision as of 17:17, 29 October 2018
Adult T-cell leukemia Microchapters |
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Adult T-cell leukemia classification On the Web |
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Risk calculators and risk factors for Adult T-cell leukemia classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Based on both the clinical presentation and laboratory findings, adult T-cell leukemia may be classified into either an acute variant, chronic variant, smoldering variant, or an adult T-cell lymphoma variant.
Classification
- Based on both the clinical presentation and laboratory findings, adult T-cell leukemia may be classified into either an acute variant, chronic variant, smouldering variant, or an adult T-cell lymphoma variant.[1][2]
- The table below lists the adult T-cell leukemia clinical classification details:
Clinical Variant | Description |
---|---|
Acute adult T-cell leukemia |
|
Chronic adult T-cell leukemia |
|
Smoldering adult T-cell leukemia |
|
Adult T-cell lymphoma |
|
References
- ↑ Matutes E (2007). "Adult T-cell leukaemia/lymphoma". J Clin Pathol. 60 (12): 1373–7. doi:10.1136/jcp.2007.052456. PMC 2095573. PMID 18042693.
- ↑ Shimoyama M (1991). "Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984-87)". Br J Haematol. 79 (3): 428–37. PMID 1751370.